Article
Pediatrics
Thilde Nordmann Winther, Alex Yde Nielsen, Allan Lund, Fin Stolze Larsen, Marianne Horby Jorgensen
Summary: This study retrospectively evaluated a systematic diagnostic approach to paediatric acute liver failure (P-ALF) in Denmark and collected nationwide epidemiological data. The results showed that identifying the aetiology in 82% of cases led to improved outcomes for P-ALF. Therefore, establishing the cause is of great significance for treatment and prognosis.
Article
Geriatrics & Gerontology
Junpeng Liu, Ke Chai, Wanrong Zhu, Minghui Du, Chen Meng, Lin Yang, Lingling Cui, Di Guo, Ning Sun, Hua Wang, Jiefu Yang
Summary: This study evaluated frailty in a cohort of patients with atrial fibrillation (AF) according to different criteria, and studied the prevalence and prognostic impact of frailty on clinical outcomes. The study found that multidimensional frailty was more significantly associated with a composite of all-cause mortality or rehospitalization within 1 year than physical frailty in older people with AF, but these associations were attenuated after multivariate adjustment.
Review
Gastroenterology & Hepatology
Peter Lemmer, Jan-Peter Sowa, Yesim Bulut, Pavel Strnad, Ali Canbay
Summary: This review discusses the mechanisms, treatments, and issues of acute liver failure (ALF). ALF is characterized by massive hepatocyte death, with the possibility of compensatory hyperplasia and functional recovery. Despite maximum therapeutic intervention, ALF still has a high mortality rate. Emergency liver transplantation and machine perfusion improve the prognosis of ALF patients.
LIVER INTERNATIONAL
(2023)
Article
Oncology
Zhehuang Li, Liangyu Guo, Bairu Guo, Peng Zhang, Jiaqiang Wang, Xin Wang, Weitao Yao
Summary: This study compared the predictive performance of seven commonly used prognostic scoring systems for surgically treated spine metastases and found that none of the scoring systems could perform optimally at all time points and for all pathology types. The reference survival times provided in the original study need to be updated, and it is important to be aware of the underestimation for current patients.
Article
Oncology
Jeanne Tie, Joshua D. Cohen, Serigne N. Lo, Yuxuan Wang, Lu Li, Michael Christie, Margaret Lee, Rachel Wong, Suzanne Kosmider, Iain Skinner, Hui Li Wong, Belinda Lee, Matthew E. Burge, Desmond Yip, Christos S. Karapetis, Timothy J. Price, Niall C. Tebbutt, Andrew M. Haydon, Janine Ptak, Mary J. Schaeffer, Natalie Silliman, Lisa Dobbyn, Maria Popoli, Cristian Tomasetti, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein, Peter Gibbs
Summary: Studies have shown that postoperative ctDNA analysis is prognostically significant in nonmetastatic CRC patients, with higher predictive accuracy for recurrence compared to clinicopathologic risk factors, and increasing mutant allele frequency (MAF) further stratifying recurrence risk.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Oncology
Lei Hu, Kang Yang, Yue Chen, Chenyu Sun, Xu Wang, Shaopu Zhu, Shiyi Yang, Guodong Cao, Maoming Xiong, Bo Chen
Summary: The nomogram developed in this study could assist in individualizing the treatment of gastric cancer patients and facilitate shared decision-making between clinicians and patients.
FRONTIERS IN ONCOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiaojie Zhang, Shaomin Yang, Shali Hao, Jiahuan Li, Min Qiu, Haixiong Chen, Yuli Huang
Summary: Heart failure with preserved ejection fraction (HFpEF) is a syndrome with significant clinical heterogeneity, where myocardial fibrosis is commonly involved in its development and progress. This study confirms that myocardial fibrosis, evaluated by cardiovascular magnetic resonance (CMR), can predict a poor prognosis in patients with HFpEF.
EUROPEAN RADIOLOGY
(2023)
Review
Nutrition & Dietetics
Arnav Mehta, Lorenzo De Paola, Tiberiu A. Pana, Ben Carter, Roy L. Soiza, Mohannad W. Kafri, John F. Potter, Mamas A. Mamas, Phyo K. Myint
Summary: This study systematically reviewed several prospective cohort studies and found that the nutritional status of stroke patients is associated with their outcomes. Underweight and low serum albumin levels increase the risk of death, while overweight and obesity reduce the risk of death.
Review
Oncology
Sin-Hye Park, Tung Hoang, Jeongseon Kim
Summary: This study examines the relationship between dietary factors and breast cancer prognosis among breast cancer survivors through systematic review and meta-analysis. It finds that unhealthy dietary patterns such as beer and saturated fat intake may worsen breast cancer prognosis, while supplementation of most vitamins is beneficial. The study suggests that developing dietary guidelines based on these findings could improve the prognosis for breast cancer survivors.
Article
Oncology
Ruohan Yang, Guanyu Lu, Zheng Lv, Lin Jia, Jiuwei Cui
Summary: This study retrospectively analyzed the clinical characteristics and prognosis of patients with breast cancer VC. The results showed variations in prognosis among different types of VC, with BMM patients having the best prognosis and DLM patients having the worst. ECOG scores and VC type were associated with survival.
FRONTIERS IN ONCOLOGY
(2022)
Review
Pharmacology & Pharmacy
Xiaofeng Luo, Xi Chen, Lin Wang, Bowen Yang, Shuang Cai
Summary: The combination of metformin and antineoplastic agents showed significant improvement in overall survival and progression-free survival outcomes in lung cancer patients, especially in non-diabetic patients. However, further investigation is needed to confirm these findings, as limited data from randomized controlled trials showed no differences in survival outcomes.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Endocrinology & Metabolism
Wen-wu Dong, Da-Lin Zhang, Zhi-Hong Wang, Cheng-Zhou Lv, Ping Zhang, Hao Zhang
Summary: Compared with non-diabetic individuals, patients with any type of diabetes have a higher risk of developing thyroid cancer. There is a positive correlation between type 2 diabetes and thyroid cancer risk in both men and women. Gestational diabetes is associated with an increased risk of thyroid cancer, while type 1 diabetes is only associated with thyroid cancer risk in women.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Infectious Diseases
Benoit Schwartz, Vincent Dupont, Sandra Dury, Aline Carsin-Vu, Thomas Guillard, Sophie Caillard, Luc Frimat, Stephane Sanchez, Betoul Schvartz, Firouze Bani-Sadr, Damien Jolly, Philippe Rieu, Antoine Goury
Summary: This retrospective study aimed to assess the characteristics and outcomes of community-acquired pneumonia (CAP) in kidney transplant recipients in France. The findings showed that more than one-third of CAP episodes in these patients were caused by identified microorganisms, including drug-resistant and opportunistic pathogens. Some patients required intensive care and mechanical ventilation.
CLINICAL MICROBIOLOGY AND INFECTION
(2023)
Review
Biotechnology & Applied Microbiology
Kang Chen, Jian-Xin Gan, Ze-Ping Huang, Jun Liu, Hai-Peng Liu
Summary: The meta-analysis and bioinformatics analysis revealed that the upregulated expression of MNX1-AS1 in various cancers is closely associated with poor survival outcomes and aggressive clinicopathological characteristics.
Review
Clinical Neurology
Zicheng Cheng, Wenyuan Zhang, Zhenxiang Zhan, Lingfan Xia, Zhao Han
Summary: In patients with spontaneous intracerebral hemorrhage, cerebral small vessel disease markers and the total burden of the disease are associated with functional outcome, mortality, stroke recurrence, and hematoma expansion.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Health Care Sciences & Services
Robert D. Herbert, Jessica Kasza, Kari Bo
BMC MEDICAL RESEARCH METHODOLOGY
(2018)
Article
Neurosciences
Peter W. Stubbs, Lee D. Walsh, Arkiev D'Souza, Martin E. Heroux, Bart Bolsterlee, Simon C. Gandevia, Robert D. Herbert
JOURNAL OF PHYSIOLOGY-LONDON
(2018)
Article
Multidisciplinary Sciences
Robert D. Herbert, Carolyn R. Broderick, Chris Barnes, Laurent Billot, Albert Zhou, Jane Latimer
Article
Orthopedics
Flavia Ignacio Antonio, Robert D. Herbert, Kari Bo, Ana Carolina Japur Sa Rosa-e-Silva, Lucia Alves Silva Lara, Maira de Menezes Franco, Cristine Homsi Jorge Ferreira
JOURNAL OF PHYSIOTHERAPY
(2018)
Editorial Material
Physiology
R. D. Herbert, S. C. Gandevia
JOURNAL OF APPLIED PHYSIOLOGY
(2019)
Review
Physiology
R. D. Herbert, B. Bolsterlee, S. C. Gandevia
JOURNAL OF APPLIED PHYSIOLOGY
(2019)
Article
Biophysics
Bart Bolsterlee, Arkiev D'Souza, Robert D. Herbert
JOURNAL OF BIOMECHANICS
(2019)
Article
Multidisciplinary Sciences
Joanna Diong, Martin E. Heroux, Simon C. Gandevia, Robert D. Herbert
Article
Engineering, Biomedical
Arkiev D'Souza, Bart Bolsterlee, Ann Lancaster, Robert D. Herbert
CLINICAL BIOMECHANICS
(2019)
Article
Public, Environmental & Occupational Health
R. D. Herbert, J. L. Taylor, S. R. Lord, S. C. Gandevia
Article
Physiology
Martin Eric Heroux, Ida Anderman, Sofia Nykvist Vouis, Joanna Diong, Peter William Stubbs, Robert D. Herbert
JOURNAL OF APPLIED PHYSIOLOGY
(2020)
Review
Orthopedics
Said Mohamad Sayah, Sascha Karunaratne, Paula R. Beckenkamp, Mark Horsley, Mark J. Hancock, David J. Hunter, Robert D. Herbert, Tarcisio F. de Campos, Daniel Steffens
Summary: This study conducted a comprehensive investigation on over 59,000 patients undergoing TKA, finding that the recovery of pain and function in the first year postoperatively is large and rapid but incomplete. However, at 10 years postoperatively, the gains in pain scores may still remain while there is an improvement in function.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Anesthesiology
V. P. Moen, A. T. Tveter, R. D. Herbert, K. B. Hagen
Summary: This study developed prediction models and externally validated them in patients with chronic widespread pain and fibromyalgia. The complexity of the models may reduce their clinical utility, while simple models were nearly as accurate and more practical.
EUROPEAN JOURNAL OF PAIN
(2022)
Article
Anesthesiology
Mary O'Keeffe, Giovanni E. Ferreira, Ian A. Harris, Ben Darlow, Rachelle Buchbinder, Adrian C. Traeger, Joshua R. Zadro, Rob D. Herbert, Rae Thomas, Joletta Belton, Chris G. Maher
Summary: This study found that labeling low back pain with different diagnostic labels can influence people's beliefs about imaging, surgery, second opinion, seriousness, recovery, work, and physical activities. Labeling low back pain as "episode of back pain", "lumbar sprain", and "non-specific LBP" can reduce the perceived need for imaging, surgery, and second opinion, as well as decrease the perceived seriousness of low back pain and enhance recovery expectations.
EUROPEAN JOURNAL OF PAIN
(2022)
Article
Clinical Neurology
Lisa A. Harvey, Joanne V. Glinsky, Robert D. Herbert
