Shedding of the tumor necrosis factor (TNF) receptor from the surface of hepatocytes during sepsis limits inflammation through cGMP signaling

A disintegrin and metalloproteinase 17 regulates TNF and TNFR1 levels in inflammation and liver regeneration in mice

(2013) Ryan S. McMahan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Tumour necrosis factor receptors and apoptosis of alveolar macrophages during early infection with attenuated and virulentMycobacterium bovis

(2013) Michele F. Rodrigues et al.   IMMUNOLOGY

Shedding of Tumor Necrosis Factor Receptor 1 Induced by Protein A Decreases Tumor Necrosis Factor Alpha Availability and Inflammation during Systemic Staphylococcus aureus Infection

(2013) Constanza Giai et al.   INFECTION AND IMMUNITY

Intestinal Epithelial Toll-Like Receptor 4 Regulates Goblet Cell Development and Is Required for Necrotizing Enterocolitis in Mice

(2012) Chhinder P. Sodhi et al.   GASTROENTEROLOGY

A Role for cGMP in Inducible Nitric-oxide Synthase (iNOS)-induced Tumor Necrosis Factor (TNF) α-converting Enzyme (TACE/ADAM17) Activation, Translocation, and TNF Receptor 1 (TNFR1) Shedding in Hepatocytes

(2012) R. Savanh Chanthaphavong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DAMPs, PAMPs, and the Origins of SIRS in Bacterial Sepsis

(2012) Lori F. Gentile et al.   SHOCK

Characterization of DISC Formation and TNFR1 Translocation to Mitochondria in TNF-α–Treated Hepatocytes

(2011) Hyun-Ae Eum et al.   AMERICAN JOURNAL OF PATHOLOGY

Sildenafil treatment attenuates lung and kidney injury due to overproduction of oxidant activity in a rat model of sepsis: a biochemical and histopathological study

(2011) E. Cadirci et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Nitric oxide signaling: Classical, less classical, and nonclassical mechanisms

(2011) Antonio Martínez-Ruiz et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of TNFR1 ectodomain shedding by mitochondrial Ca2+ determines the severity of inflammation in mouse lung microvessels

(2011) David J. Rowlands et al.   JOURNAL OF CLINICAL INVESTIGATION

What the Myddosome structure tells us about the initiation of innate immunity

(2011) Nicholas J. Gay et al.   TRENDS IN IMMUNOLOGY

Bundled care for septic shock: An analysis of clinical trials*

(2010) Amisha V. Barochia et al.   CRITICAL CARE MEDICINE

A Novel Pathway for Inducible Nitric-oxide Synthase Activation through Inflammasomes

(2010) Carina L. Buzzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Double-Stranded RNA Induces Shedding of the 34-kDa Soluble TNFR1 from Human Airway Epithelial Cells via TLR3-TRIF-RIP1-Dependent Signaling: Roles for Dual Oxidase 2- and Caspase-Dependent Pathways

(2010) M. Yu et al.   JOURNAL OF IMMUNOLOGY

sGCα1β1 attenuates cardiac dysfunction and mortality in murine inflammatory shock models

(2009) Emmanuel S. Buys et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Removal of silicone oil droplet adhering to a silicone intraocular lens using 25-gauge instrumentation

(2009) Susumu Sakimoto et al.   JOURNAL OF CATARACT AND REFRACTIVE SURGERY

A Far-Upstream Oct-1 Motif Regulates Cytokine-Induced Transcription of the Human Inducible Nitric Oxide Synthase Gene

(2009) Kyung Soo Park et al.   JOURNAL OF MOLECULAR BIOLOGY

Immunodesign of experimental sepsis by cecal ligation and puncture

(2009) Daniel Rittirsch et al.   Nature Protocols