Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptake

The miR-199-dynamin regulatory axis controls receptor-mediated endocytosis

(2015) J. F. Aranda et al.   JOURNAL OF CELL SCIENCE

Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP

(2015) S J H Ricoult et al.   ONCOGENE

Targeting SREBP-1-driven Lipid Metabolism to Treat Cancer

(2015) Deliang Guo et al.   CURRENT PHARMACEUTICAL DESIGN

Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice

(2014) Lawrence A. Scheving et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Dissociated presenilin-1 and TACE processing of ErbB4 in lung alveolar type II cell differentiation

(2014) Najla Fiaturi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Convergent and Divergent Cellular Responses by ErbB4 Isoforms in Mammary Epithelial Cells

(2014) Vikram B. Wali et al.   MOLECULAR CANCER RESEARCH

Neuregulin-ERBB Signaling in the Nervous System and Neuropsychiatric Diseases

(2014) Lin Mei et al.   NEURON

Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration

(2014) J. W. Haskins et al.   Science Signaling

The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility

(2014) T. Kiuchi et al.   Science Signaling

Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes

(2014) Saravana M. Dhanasekaran et al.   Nature Communications

Molecular Pathways: Sterols and Receptor Signaling in Cancer

(2013) L. Gabitova et al.   CLINICAL CANCER RESEARCH

Blocking NRG1 and Other Ligand-Mediated Her4 Signaling Enhances the Magnitude and Duration of the Chemotherapeutic Response of Non-Small Cell Lung Cancer

(2013) G. V. Hegde et al.   Science Translational Medicine

A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products

(2012) James R. Krycer et al.   BIOCHEMICAL JOURNAL

Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway

(2012) William A. Freed-Pastor et al.   CELL

Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitro

(2012) Alberto Canfrán-Duque et al.   JOURNAL OF LIPID RESEARCH

An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR-Dependent Pathway

(2011) D. Guo et al.   Cancer Discovery

Interactions of ErbB4 and Kap1 Connect the Growth Factor and DNA Damage Response Pathways

(2010) Maureen Gilmore-Hebert et al.   MOLECULAR CANCER RESEARCH

Dysregulation of the mevalonate pathway promotes transformation

(2010) J. W. Clendening et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G-protein-coupled receptors, cholesterol and palmitoylation: facts about fats

(2009) Bice Chini et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

ErbB4 Splice Variants Cyt1 and Cyt2 Differ by 16 Amino Acids and Exert Opposing Effects on the Mammary Epithelium In Vivo

(2009) R. S. Muraoka-Cook et al.   MOLECULAR AND CELLULAR BIOLOGY

EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy

(2009) D. Guo et al.   Science Signaling

ErbB4/HER4: Role in Mammary Gland Development, Differentiation and Growth Inhibition

(2008) Rebecca S. Muraoka-Cook et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Role of ErbB4 in Breast Cancer

(2008) Maria Sundvall et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA