标题
Antigen-based vs. systemic immunomodulation in type 1 diabetes
作者
关键词
-
出版物
Islets
Volume 5, Issue 2, Pages 53-66
出版商
Informa UK Limited
发表日期
2013-06-12
DOI
10.4161/isl.24785
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials
- (2013) Antoinette Moran et al. LANCET
- Rapamycin/IL-2 Combination Therapy in Patients With Type 1 Diabetes Augments Tregs yet Transiently Impairs -Cell Function
- (2012) S. A. Long et al. DIABETES
- Low doses of anti-CD3, ciclosporin A and the vitamin D analogue, TX527, synergise to delay recurrence of autoimmune diabetes in an islet-transplanted NOD mouse model of diabetes
- (2012) F. Baeke et al. DIABETOLOGIA
- Pathogenesis of NOD diabetes is initiated by reactivity to the insulin B chain 9-23 epitope and involves functional epitope spreading
- (2012) Suchitra Prasad et al. JOURNAL OF AUTOIMMUNITY
- Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice
- (2012) Tatiana Takiishi et al. JOURNAL OF CLINICAL INVESTIGATION
- GAD65 Antigen Therapy in Recently Diagnosed Type 1 Diabetes Mellitus
- (2012) Johnny Ludvigsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Teplizumab Induces Human Gut-Tropic Regulatory Cells in Humanized Mice and Patients
- (2012) F. Waldron-Lynch et al. Science Translational Medicine
- Antigen-Based Immune Therapeutics for Type 1 Diabetes: Magic Bullets or Ordinary Blanks?
- (2011) Slobodan Culina et al. Clinical & Developmental Immunology
- Synergistic Reversal of Type 1 Diabetes in NOD Mice With Anti-CD3 and Interleukin-1 Blockade: Evidence of Improved Immune Regulation
- (2011) V. Ablamunits et al. DIABETES
- Islet Amyloid Polypeptide Is a Target Antigen for Diabetogenic CD4+ T Cells
- (2011) T. Delong et al. DIABETES
- Evidence That Nasal Insulin Induces Immune Tolerance to Insulin in Adults With Autoimmune Diabetes
- (2011) S. Fourlanos et al. DIABETES
- Impact of Intranasal Insulin on Insulin Antibody Affinity and Isotypes in Young Children With HLA-Conferred Susceptibility to Type 1 Diabetes
- (2011) S. J. Ryhanen et al. DIABETES CARE
- Long-Term Outcome of Individuals Treated With Oral Insulin: Diabetes Prevention Trial-Type 1 (DPT-1) oral insulin trial
- (2011) K. Vehik et al. DIABETES CARE
- The effect of vitamin D supplementation on peripheral regulatory T cells and β cell function in healthy humans: a randomized controlled trial
- (2011) Gerlies Bock et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Preservation of recall immunity in anti-CD3-treated recent onset type 1 diabetes patients
- (2011) Gonnie M. Alkemade et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Insulin as a key autoantigen in the development of type 1 diabetes
- (2011) Maki Nakayama DIABETES-METABOLISM RESEARCH AND REVIEWS
- Oral tolerance
- (2011) Howard L. Weiner et al. IMMUNOLOGICAL REVIEWS
- The Role of Autoantibodies to Zinc Transporter 8 in Prediction of Type 1 Diabetes in Relatives: Lessons from the European Nicotinamide Diabetes Intervention Trial (ENDIT) Cohort
- (2011) Anna E. Long et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Anti-CD3 Therapy Promotes Tolerance by Selectively Depleting Pathogenic Cells while Preserving Regulatory T Cells
- (2011) C. Penaranda et al. JOURNAL OF IMMUNOLOGY
- Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial
- (2011) Diane K Wherrett et al. LANCET
- Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial
- (2011) Nicole Sherry et al. LANCET
- Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial
- (2011) Tihamer Orban et al. LANCET
- Human CD3 Transgenic Mice: Preclinical Testing of Antibodies Promoting Immune Tolerance
- (2011) C. Kuhn et al. Science Translational Medicine
- No Effect of the 1 ,25-Dihydroxyvitamin D3 on -Cell Residual Function and Insulin Requirement in Adults With New-Onset Type 1 Diabetes
- (2010) M. Walter et al. DIABETES CARE
- Extended evaluation of the safety and efficacy of GAD treatment of children and adolescents with recent-onset type 1 diabetes: a randomised controlled trial
- (2010) J. Ludvigsson et al. DIABETOLOGIA
- Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass
- (2010) B. Keymeulen et al. DIABETOLOGIA
- Immunotherapy of type 1 diabetes — How to rationally prioritize combination therapies in T1D
- (2010) Tobias Boettler et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor–specified peripheral niche constraints
- (2010) Junko Nishio et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Genetics, pathogenesis and clinical interventions in type 1 diabetes
- (2010) Jeffrey A. Bluestone et al. NATURE
- Chromogranin A is an autoantigen in type 1 diabetes
- (2010) Brian D Stadinski et al. NATURE IMMUNOLOGY
- Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients
- (2009) B. Keymeulen et al. BLOOD
- Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years
- (2009) Kevan C. Herold et al. CLINICAL IMMUNOLOGY
- Insulin treatment in IA-2A-positive relatives of type 1 diabetic patients
- (2009) E. Vandemeulebroucke et al. DIABETES & METABOLISM
- Pancreatic Islet Autoantibodies as Predictors of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1
- (2009) T. Orban et al. DIABETES CARE
- Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes
- (2009) C. M. Larsen et al. DIABETES CARE
- Therapy with GAD in diabetes
- (2009) Johnny Ludvigsson DIABETES-METABOLISM RESEARCH AND REVIEWS
- Immune modulation in type 1 diabetes mellitus using DiaPep277: a short review and update of recent clinical trial results
- (2009) Roy Eldor et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- The anti-interleukin-1 in type 1 diabetes action trial-background and rationale
- (2009) Linda M.S. Pickersgill et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Protective effects of 1-α-hydroxyvitamin D3 on residual β-cell function in patients with adult-onset latent autoimmune diabetes (LADA)
- (2009) Xia Li et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- GAD65 vaccination: 5 years of follow-up in a randomised dose-escalating study in adult-onset autoimmune diabetes
- (2009) C.-D. Agardh et al. DIABETOLOGIA
- The clinical utility of inhibiting CD28-mediated costimulation
- (2009) Peter S. Linsley et al. IMMUNOLOGICAL REVIEWS
- CD28 and CTLA-4 coreceptor expression and signal transduction
- (2009) Christopher E. Rudd et al. IMMUNOLOGICAL REVIEWS
- C-Peptide Levels and Insulin Independence Following Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus
- (2009) Carlos E. B. Couri JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy
- (2009) Tihamer Orban et al. JOURNAL OF AUTOIMMUNITY
- Pancreatic duodenal homeobox 1 protein is a novel β-cell-specific autoantigen for type I diabetes
- (2009) Shi-Wu Li et al. LABORATORY INVESTIGATION
- Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study
- (2009) Christopher C Patterson et al. LANCET
- Genetic-induced Variations in the GAD65 T-cell Repertoire Governs Efficacy of Anti-CD3/GAD65 Combination Therapy in New-onset Type 1 Diabetes
- (2009) Damien Bresson et al. MOLECULAR THERAPY
- Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function
- (2009) Mark D. Pescovitz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Autoimmune mechanisms in type 1 diabetes
- (2008) Mikael Knip et al. AUTOIMMUNITY REVIEWS
- Modulating the natural history of type 1 diabetes in children at high genetic risk by mucosal insulin immunization
- (2008) Peter Achenbach et al. Current Diabetes Reports
- Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial
- (2008) Kirsti Näntö-Salonen et al. LANCET
- Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
- (2008) Stephanie C. Eisenbarth et al. NATURE
- GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes
- (2008) Johnny Ludvigsson et al. NEW ENGLAND JOURNAL OF MEDICINE
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