An emerging role for NAADP-mediated Ca2+signaling in the pancreatic β-cell

Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca2+ Signaling and Endolysosomal Trafficking

(2010) Margarida Ruas et al.   CURRENT BIOLOGY

Acute Insulin Signaling in Pancreatic Beta-Cells Is Mediated by Multiple Raf-1 Dependent Pathways

(2010) Emilyn U. Alejandro et al.   ENDOCRINOLOGY

TRPM5 regulates glucose-stimulated insulin secretion

(2010) Lili R. Brixel et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice

(2010) B. Colsoul et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin receptor signaling for the proliferation of pancreatic β-cells: Involvement of Ca2+second messengers, IP3, NAADP and cADPR

(2010) Asif Iqbal Shawl et al.   Islets

Calcium signaling via two-pore channels: local or global, that is the question

(2009) Michael X. Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The contribution of incretin hormones to the pathogenesis of type 2 diabetes

(2009) Juris J. Meier   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Second Messenger Signaling: Multiple Receptors for NAADP

(2009) Andreas H. Guse   CURRENT BIOLOGY

Shortcomings of current models of glucose-induced insulin secretion

(2009) J. C. Henquin et al.   DIABETES OBESITY & METABOLISM

CD38-mediated Ca2+Signaling Contributes to Angiotensin II-induced Activation of Hepatic Stellate Cells

(2009) Seon-Young Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

(2009) Eugen Brailoiu et al.   JOURNAL OF CELL BIOLOGY

NAADP mobilizes calcium from acidic organelles through two-pore channels

(2009) Peter J. Calcraft et al.   NATURE

Identification of a chemical probe for NAADP by virtual screening

(2009) Edmund Naylor et al.   Nature Chemical Biology

The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca2+ release channels

(2009) Antony Galione et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores

(2009) Xiangang Zong et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist

(2009) W. Dammermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ca2+ Signaling Occurs via Second Messenger Release from Intraorganelle Synthesis Sites

(2008) Lianne C. Davis et al.   CURRENT BIOLOGY

Generation of Nicotinic Acid Adenine Dinucleotide Phosphate and Cyclic ADP-Ribose by Glucagon-Like Peptide-1 Evokes Ca2+ Signal That Is Essential for Insulin Secretion in Mouse Pancreatic Islets

(2008) B.-J. Kim et al.   DIABETES

Investigating cADPR and NAADP in intact and broken cell preparations

(2008) Anthony J. Morgan et al.   METHODS

TRPM4 impacts on Ca2+ signals during agonist-induced insulin secretion in pancreatic β-cells

(2008) V. Marigo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology

(2008) Fabio Malavasi et al.   PHYSIOLOGICAL REVIEWS