Exploiting ecological principles to better understand cancer progression and treatment

Exploiting Evolution To Treat Drug Resistance: Combination Therapy and the Double Bind

(2012) David Basanta et al.   MOLECULAR PHARMACEUTICS

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Evolving homeostatic tissue using genetic algorithms

(2011) Philip Gerlee et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Modeling Evolutionary Dynamics of Epigenetic Mutations in Hierarchically Organized Tumors

(2011) Andrea Sottoriva et al.   PLoS Computational Biology

A theoretical quantitative model for evolution of cancer chemotherapy resistance

(2010) Ariosto S Silva et al.   Biology Direct

Cancer Stem Cell Tumor Model Reveals Invasive Morphology and Increased Phenotypical Heterogeneity

(2010) A. Sottoriva et al.   CANCER RESEARCH

Chemotherapy enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice

(2010) Rupal Ramakrishnan et al.   JOURNAL OF CLINICAL INVESTIGATION

Microenvironmental Independence Associated with Tumor Progression

(2009) A. R.A. Anderson et al.   CANCER RESEARCH

Adaptive Therapy

(2009) R. A. Gatenby et al.   CANCER RESEARCH

Studying the emergence of invasiveness in tumours using game theory

(2008) D. Basanta et al.   EUROPEAN PHYSICAL JOURNAL B

A hybrid cellular automaton model of clonal evolution in cancer: The emergence of the glycolytic phenotype

(2008) P. Gerlee et al.   JOURNAL OF THEORETICAL BIOLOGY

Invasion emerges from cancer cell adaptation to competitive microenvironments: Quantitative predictions from multiscale mathematical models

(2008) Vito Quaranta et al.   SEMINARS IN CANCER BIOLOGY

The Evolution of Robust Development and Homeostasis in Artificial Organisms

(2008) David Basanta et al.   PLoS Computational Biology