The functional and anatomical dissection of somatosensory subpopulations using mouse genetics

Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn

(2014) Rita Bardoni et al.   NEURON

The Epithelial Cell-Derived Atopic Dermatitis Cytokine TSLP Activates Neurons to Induce Itch

(2013) Sarah R. Wilson et al.   CELL

DREADDs: novel tools for drug discovery and development

(2013) Hyeong-Min Lee et al.   DRUG DISCOVERY TODAY

The Cellular Code for Mammalian Thermosensation

(2013) L. A. Pogorzala et al.   JOURNAL OF NEUROSCIENCE

Ontogeny of Excitatory Spinal Neurons Processing Distinct Somatic Sensory Modalities

(2013) Y. Xu et al.   JOURNAL OF NEUROSCIENCE

Remote Optogenetic Activation and Sensitization of Pain Pathways in Freely Moving Mice

(2013) I. Daou et al.   JOURNAL OF NEUROSCIENCE

Runx1 Controls Terminal Morphology and Mechanosensitivity of VGLUT3-expressing C-Mechanoreceptors

(2013) S. Lou et al.   JOURNAL OF NEUROSCIENCE

Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo

(2013) Sophia Vrontou et al.   NATURE

Excitatory Superficial Dorsal Horn Interneurons Are Functionally Heterogeneous and Required for the Full Behavioral Expression of Pain and Itch

(2013) Xidao Wang et al.   NEURON

The Sensory Neurons of Touch

(2013) Victoria E. Abraira et al.   NEURON

Peptidergic CGRPα Primary Sensory Neurons Encode Heat and Itch and Tonically Suppress Sensitivity to Cold

(2013) Eric S. McCoy et al.   NEURON

The Organization of Submodality-Specific Touch Afferent Inputs in the Vibrissa Column

(2013) Katsuyasu Sakurai et al.   Cell Reports

The Molecular and Cellular Basis of Cold Sensation

(2012) David D. McKemy   ACS Chemical Neuroscience

Mechanisms of Itch Evoked by  -Alanine

(2012) Q. Liu et al.   JOURNAL OF NEUROSCIENCE

A subpopulation of nociceptors specifically linked to itch

(2012) Liang Han et al.   NATURE NEUROSCIENCE

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

(2012) Linda Madisen et al.   NATURE NEUROSCIENCE

Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons

(2012) Michael S. Minett et al.   Nature Communications

The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

(2011) Lishi Li et al.   CELL

Restriction of Transient Receptor Potential Vanilloid-1 to the Peptidergic Subset of Primary Afferent Neurons Follows Its Developmental Downregulation in Nonpeptidergic Neurons

(2011) D. J. Cavanaugh et al.   JOURNAL OF NEUROSCIENCE

Trpv1 Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells

(2011) D. J. Cavanaugh et al.   JOURNAL OF NEUROSCIENCE

TRPA1 is required for histamine-independent, Mas-related G protein–coupled receptor–mediated itch

(2011) Sarah R Wilson et al.   NATURE NEUROSCIENCE

Molecular mechanisms of mechanotransduction in mammalian sensory neurons

(2011) Patrick Delmas et al.   NATURE REVIEWS NEUROSCIENCE

Facilitation of μ-Opioid Receptor Activity by Preventing δ-Opioid Receptor-Mediated Codegradation

(2011) Shao-Qiu He et al.   NEURON

TRPM3 Is a Nociceptor Channel Involved in the Detection of Noxious Heat

(2011) Joris Vriens et al.   NEURON

TRPV1-lineage neurons are required for thermal sensation

(2010) Santosh K Mishra et al.   EMBO JOURNAL

Toll-like receptor 7 mediates pruritus

(2010) Tong Liu et al.   NATURE NEUROSCIENCE

TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus

(2010) Andrés E Chávez et al.   NATURE NEUROSCIENCE

Postsynaptic TRPV1 triggers cell type–specific long-term depression in the nucleus accumbens

(2010) Brad A Grueter et al.   NATURE NEUROSCIENCE

Sensing Muscle Ischemia: Coincident Detection of Acid and ATP via Interplay of Two Ion Channels

(2010) William T. Birdsong et al.   NEURON

Loss of Inhibitory Interneurons in the Dorsal Spinal Cord and Elevated Itch in Bhlhb5 Mutant Mice

(2010) Sarah E. Ross et al.   NEURON

TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo

(2010) Wendy M. Knowlton et al.   PAIN

Coexpression of  - and  -opioid receptors in nociceptive sensory neurons

(2010) H.-B. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus

(2009) Qin Liu et al.   CELL

Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain

(2009) Grégory Scherrer et al.   CELL

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Mrgprd-Expressing Polymodal Nociceptive Neurons Innervate Most Known Classes of Substantia Gelatinosa Neurons

(2009) H. Wang et al.   JOURNAL OF NEUROSCIENCE

Ablation of TrpV1 neurons reveals their selective role in thermal pain sensation

(2009) Santosh K. Mishra et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

(2009) Rebecca P. Seal et al.   NATURE

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

(2009) Lin Tian et al.   NATURE METHODS

TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms

(2009) N. Imamachi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

(2009) D. J. Cavanaugh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Basis of Itch Sensation

(2009) Y.-G. Sun et al.   SCIENCE

Hot flash: TRPV channels in the brain

(2009) Julie A. Kauer et al.   TRENDS IN NEUROSCIENCES

Cutaneous Sensory Neurons Expressing the Mrgprd Receptor Sense Extracellular ATP and Are Putative Nociceptors

(2008) G. Dussor et al.   JOURNAL OF NEUROPHYSIOLOGY

Visualizing Cold Spots: TRPM8-Expressing Sensory Neurons and Their Projections

(2008) A. Dhaka et al.   JOURNAL OF NEUROSCIENCE

Genetic control of neuronal activity in mice conditionally expressing TRPV1

(2008) Benjamin R Arenkiel et al.   NATURE METHODS

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY

Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3

(2008) Rebecca P. Seal et al.   NEURON

The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain

(2008) B. Abrahamsen et al.   SCIENCE