Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model
出版年份 2015 全文链接
标题
Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model
作者
关键词
Autism spectrum disorders, Purinergic signaling, Antipurinergic therapy (APT), Mitochondria, Metabolism, Metabolomics, Fragile X syndrome, Genetics, Environment, Maternal immune activation (MIA), Cell danger response (CDR)
出版物
Molecular Autism
Volume 6, Issue 1, Pages 1
出版商
Springer Nature
发表日期
2015-06-18
DOI
10.1186/2040-2392-6-1
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Ca2+signals, NAADP and two-pore channels: role in cellular differentiation
- (2014) J. Parrington et al. Acta Physiologica
- The biochemistry and cell biology of aging: metabolic regulation through mitochondrial signaling
- (2014) Yun Chau Long et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Biology of purinergic signalling: Its ancient evolutionary roots, its omnipresence and its multiple functional significance
- (2014) Alexei Verkhratsky et al. BIOESSAYS
- A Chromatin-Dependent Role of the Fragile X Mental Retardation Protein FMRP in the DNA Damage Response
- (2014) Roman Alpatov et al. CELL
- Fragile X Mental Retardation Protein Regulates Translation by Binding Directly to the Ribosome
- (2014) Eileen Chen et al. MOLECULAR CELL
- Pharmacological Rescue of Cortical Synaptic and Network Potentiation in a Mouse Model for Fragile X Syndrome
- (2014) Tao Chen et al. NEUROPSYCHOPHARMACOLOGY
- Mitochondrial Channels: Ion Fluxes and More
- (2014) Ildiko Szabo et al. PHYSIOLOGICAL REVIEWS
- Oxidative Stress Induces Mitochondrial Dysfunction in a Subset of Autism Lymphoblastoid Cell Lines in a Well-Matched Case Control Cohort
- (2014) Shannon Rose et al. PLoS One
- Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming
- (2014) M. Picard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered expression of Alzheimer’s disease-related genes in the cerebellum of autistic patients: a model for disrupted brain connectome and therapy
- (2014) F Zeidán-Chuliá et al. Cell Death & Disease
- Reversal of autism-like behaviors and metabolism in adult mice with single-dose antipurinergic therapy
- (2014) J C Naviaux et al. Translational Psychiatry
- Glycogen Synthase Kinase-3 Inhibitors Reverse Deficits in Long-term Potentiation and Cognition in Fragile X Mice
- (2013) Aimee V. Franklin et al. BIOLOGICAL PSYCHIATRY
- Chronic Metabotropic Glutamate Receptor 5 Inhibition Corrects Local Alterations of Brain Activity and Improves Cognitive Performance in Fragile X Mice
- (2013) Aubin Michalon et al. BIOLOGICAL PSYCHIATRY
- Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson’s disease
- (2013) Heather Mortiboys et al. BRAIN
- Regulation of Ion Channels by Pyridine Nucleotides
- (2013) Peter J. Kilfoil et al. CIRCULATION RESEARCH
- Purinergic mechanisms and pain—An update
- (2013) Geoffrey Burnstock EUROPEAN JOURNAL OF PHARMACOLOGY
- The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons
- (2013) Wenzhang Wang et al. HUMAN MOLECULAR GENETICS
- CD38 Controls the Innate Immune Response against Listeria monocytogenes
- (2013) Timo Lischke et al. INFECTION AND IMMUNITY
- A Randomized Double-Blind, Placebo-Controlled Trial of Minocycline in Children and Adolescents with Fragile X Syndrome
- (2013) Mary Jacena S. Leigh et al. JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS
- Leukotriene B4, an Endogenous Stimulator of the Innate Immune Response against Pathogens
- (2013) Manon Le Bel et al. Journal of Innate Immunity
- Linking the fragile X mental retardation protein to the lipoxygenase pathway
- (2013) Marc-Alexandre Beaulieu MEDICAL HYPOTHESES
- Targeting the endocannabinoid system in the treatment of fragile X syndrome
- (2013) Arnau Busquets-Garcia et al. NATURE MEDICINE
- TDP-43 pathology in polyglutamine diseases: With reference to amyotrphic lateral sclerosis
- (2013) Yasuko Toyoshima et al. NEUROPATHOLOGY
- Antipurinergic Therapy Corrects the Autism-Like Features in the Poly(IC) Mouse Model
- (2013) Robert K. Naviaux et al. PLoS One
- Enrichment of Elevated Plasma F2t-Isoprostane Levels in Individuals with Autism Who Are Stratified by Presence of Gastrointestinal Dysfunction
- (2013) Phillip Gorrindo et al. PLoS One
- The Housekeeping Gene Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) Regulates Multiple Developmental and Metabolic Pathways of Murine Embryonic Stem Cell Neuronal Differentiation
- (2013) Tae Hyuk Kang et al. PLoS One
- Genome-Wide Profiling of the Activity-Dependent Hippocampal Transcriptome
- (2013) Guido Hermey et al. PLoS One
- Epoxyeicosatrienoic acids protect cardiac cells during starvation by modulating an autophagic response
- (2013) V Samokhvalov et al. Cell Death & Disease
- Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder
- (2013) R E Frye et al. Translational Psychiatry
- The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease
- (2012) Alexander H. Stephan et al. Annual Review of Neuroscience
- Exploring the Relationship Between Anxiety and Insistence on Sameness in Autism Spectrum Disorders
- (2012) Katherine Gotham et al. Autism Research
- Mitochondrial and ion channel gene alterations in autism
- (2012) Moyra Smith et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Oxidative stress-related biomarkers in autism: Systematic review and meta-analyses
- (2012) Alessandra Frustaci et al. FREE RADICAL BIOLOGY AND MEDICINE
- Individual common variants exert weak effects on the risk for autism spectrum disorders
- (2012) Richard Anney et al. HUMAN MOLECULAR GENETICS
- Cyclic ADP-ribose and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) as Messengers for Calcium Mobilization
- (2012) Hon Cheung Lee JOURNAL OF BIOLOGICAL CHEMISTRY
- ATP inhibits Ins(1,4,5)P3-evoked Ca2+ release in smooth muscle via P2Y1 receptors
- (2012) D. MacMillan et al. JOURNAL OF CELL SCIENCE
- Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics
- (2012) Claudia Bagni et al. JOURNAL OF CLINICAL INVESTIGATION
- Lipid mediators in plasma of autism spectrum disorders
- (2012) Afaf El-Ansary et al. Lipids in Health and Disease
- Cholesterol, GM1, and Autism
- (2012) Cara-Lynne Schengrund et al. NEUROCHEMICAL RESEARCH
- MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis
- (2012) J. Xia et al. NUCLEIC ACIDS RESEARCH
- Maternal Metabolic Conditions and Risk for Autism and Other Neurodevelopmental Disorders
- (2012) P. Krakowiak et al. PEDIATRICS
- Brain Transcriptional and Epigenetic Associations with Autism
- (2012) Matthew R. Ginsberg et al. PLoS One
- Omega-3 fatty acids and their lipid mediators: Towards an understanding of resolvin and protectin formation
- (2012) Karsten H. Weylandt et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Traffic-Related Air Pollution, Particulate Matter, and Autism
- (2012) Heather E. Volk et al. JAMA Psychiatry
- Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism
- (2011) Joachim Hallmayer ARCHIVES OF GENERAL PSYCHIATRY
- Esterified eicosanoids: Generation, characterization and function
- (2011) Victoria J. Hammond et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Endocannabinoids and traumatic brain injury
- (2011) Esther Shohami et al. BRITISH JOURNAL OF PHARMACOLOGY
- Neurological Disorders of Purine and Pyrimidine Metabolism
- (2011) Vanna Micheli et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- What Can We Learn about Autism from Studying Fragile X Syndrome?
- (2011) Dejan B. Budimirovic et al. DEVELOPMENTAL NEUROSCIENCE
- A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder
- (2011) Jillian P. Casey et al. HUMAN GENETICS
- Impaired Carbohydrate Digestion and Transport and Mucosal Dysbiosis in the Intestines of Children with Autism and Gastrointestinal Disturbances
- (2011) Brent L. Williams et al. PLoS One
- Reversal of Fragile X Phenotypes by Manipulation of AβPP/Aβ Levels in Fmr1KO Mice
- (2011) Cara J. Westmark et al. PLoS One
- Thalamocortical dynamics of sleep: Roles of purinergic neuromodulation
- (2011) Michael M. Halassa SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Mitochondrial control of epigenetics
- (2010) Robert K. Naviaux CANCER BIOLOGY & THERAPY
- Functions and regulation of the 70kDa ribosomal S6 kinases
- (2010) Tim R. Fenton et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Functional impact of global rare copy number variation in autism spectrum disorders
- (2010) Dalila Pinto et al. NATURE
- Alterations in subcellular localization of TDP-43 immunoreactivity in the anterior horns in sporadic amyotrophic lateral sclerosis
- (2010) Shoichi Sasaki et al. NEUROSCIENCE LETTERS
- Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome
- (2010) A. Suvrathan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondria and calcium flux as targets of neuroprotection caused by minocycline in cerebellar granule cells
- (2009) Eva Maria Garcia-Martinez et al. BIOCHEMICAL PHARMACOLOGY
- Neonatal infection with neurotropic influenza A virus induces the kynurenine pathway in early life and disrupts sensorimotor gating in adult Tap1−/− mice
- (2009) Linnéa Asp et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Retained features of embryonic metabolism in the adult MRL mouse
- (2009) Robert K. Naviaux et al. MOLECULAR GENETICS AND METABOLISM
- 5-HT2A and 5-HT2C Receptors Exert Opposing Effects on Locomotor Activity in Mice
- (2009) Adam L Halberstadt et al. NEUROPSYCHOPHARMACOLOGY
- Novel plasma phospholipid biomarkers of autism: Mitochondrial dysfunction as a putative causative mechanism
- (2009) Élodie Pastural et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety
- (2009) Alexia Thomas et al. PSYCHOPHARMACOLOGY
- Purinergic signalling in autonomic control
- (2009) Alexander V. Gourine et al. TRENDS IN NEUROSCIENCES
- Social approach and repetitive behavior in eleven inbred mouse strains
- (2008) Sheryl S. Moy et al. BEHAVIOURAL BRAIN RESEARCH
- Minocycline and neurodegenerative diseases
- (2008) Hye-Sun Kim et al. BEHAVIOURAL BRAIN RESEARCH
- Neurocognitive predictors of social and communicative developmental trajectories in preschoolers with autism spectrum disorders
- (2008) JEFFREY MUNSON et al. JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
- Suramin: Clinical Uses and Structure-Activity Relationships
- (2008) Ross McGeary et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Locomotor activity, ultrasonic vocalization and oxytocin levels in infant CD38 knockout mice
- (2008) Hong-Xiang Liu et al. NEUROSCIENCE LETTERS
- Quantitative proteomic analysis of primary neurons reveals diverse changes in synaptic protein content in fmr1 knockout mice
- (2008) L. Liao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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