Editorial Material
Medicine, General & Internal
Satish K. Garg, Sarit Polsky
Summary: Compared to 1989, there have been significant advancements in insulin options and technologies that provide women with diabetes more opportunities to safely conceive and give birth.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Medicine, General & Internal
Teresa Quattrin, Lucy D. Mastrandrea, Lucy S. K. Walker
Summary: Type 1 diabetes is a chronic disease caused by autoimmune destruction of pancreatic beta cells, and individuals with this disease rely on insulin for survival. Despite advancements, the burden of this disease remains high. Research shows that blocking the immune attack on beta cells holds promise in preserving endogenous insulin production.
Article
Pediatrics
Linh A. Nguyen, Frans Pouwer, Paul Lodder, Esther Hartman, Per Winterdijk, Henk-Jan Aanstoot, Giesje Nefs
Summary: This study revealed that parental depressive and anxiety symptoms were not predictive of adolescent health outcomes 1 year later. The division of responsibility and treatment behaviors did not mediate the relationship between parental emotional distress and HbA(1c) after 1 year. Future research could explore whether these associations exist in the case of mood/anxiety disorders or severe diabetes-specific distress, or if adolescents are resilient in the face of parental distress.
PEDIATRIC RESEARCH
(2022)
Review
Health Care Sciences & Services
Claudia Eberle, Stefanie Stichling
Summary: Telemedical interventions may effectively improve diabetes control and significantly reduce HbA(1c) concentrations. The benefits of telemedicine could be greater for patients with T2DM compared to those with T1DM.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Araz Rawshani, Naveed Sattar, Darren K. McGuire, Oskar Wallstrom, Ulf Smith, Jan Boren, Goran Bergstrom, Elmir Omerovic, Annika Rosengren, Bjorn Eliasson, Deepak L. Bhatt, Aidin Rawshani
Summary: The study found that the incidence of valvular disease is increasing among patients with diabetes. In type 2 diabetes, systolic blood pressure, body mass index, and renal function were found to be associated with valvular lesions.
Review
Immunology
Balasubramanian Krishnamurthy, Matthew Lacorcia, Thomas W. H. Kay, Helen E. Thomas, Stuart I. Mannering
Summary: Type 1 diabetes (T1D) is an autoimmune disease mediated by T cells. Short-term treatment targeting T cells, B cells, and inflammatory cytokines has shown temporary disease activity pause. Lessons learned from these trials will be discussed, with the expectation that effective disease-modifying agents will be available for early-stage T1D. Advances in analyzing antigen-specific T cells and discovering biomarkers through high-dimensional profiling offer promising prospects for predicting disease onset, progression, and therapeutic efficacy.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Multidisciplinary Sciences
Procolo Di Bonito, Francesco Maria Rosanio, Maria Loredana Marcovecchio, Valentino Cherubini, Maurizio Delvecchio, Francesca Di Candia, Dario Iafusco, Angela Zanfardino, Brunella Iovane, Claudio Maffeis, Giulio Maltoni, Carlo Ripoli, Elvira Piccinno, Claudia Anita Piona, Maria Rossella Ricciardi, Riccardo Schiaffini, Adriana Franzese, Enza Mozzillo
Summary: This study aimed to investigate the association between uric acid and cardiometabolic risk factors in youth with type 1 diabetes, and found that this association varies by sex.
SCIENTIFIC REPORTS
(2022)
Article
Endocrinology & Metabolism
Anna Parkkola, Maaret Turtinen, Taina Harkonen, Jorma Ilonen, Mikael Knip
Summary: Family history of type 2 diabetes may impact the phenotype and genotype of children with type 1 diabetes, as children with a positive family history for type 2 diabetes tend to have features associated with type 2 diabetes at the time of type 1 diabetes diagnosis.
Article
Public, Environmental & Occupational Health
Ella Tuohy, Pamela Gallagher, Caroline Rawdon, Nuala Murphy, Veronica Swallow, Veronica Lambert
Summary: This study aimed to explore adolescent perspectives on communicating about self-management of type 1 diabetes (T1D) and negotiating responsibilities for self-management with parents. Semi-structured interviews were conducted with 28 adolescents living with T1D, and two themes and five subthemes were identified. The findings highlight the importance of how adolescents perceive communication with their parents in negotiating self-management responsibilities during adolescence.
PATIENT EDUCATION AND COUNSELING
(2023)
Article
Clinical Neurology
Saijun Zhang, Jun Sung Hong, Rachel C. Garthe, Dorothy L. Espelage, Hannah L. Schacter
Summary: This study investigated the impact of parental stress on adolescents' bullying involvement, revealing that parental stress may be related to adolescent bullying behavior through influencing adolescent anxiety and family resilience. Gender differences were found in these associations between male and female adolescents.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Medicine, Research & Experimental
Alvin C. Powers
Summary: Type 1 diabetes is a result of autoimmune response requiring lifelong insulin therapy. Although there is considerable heterogeneity in genetics, pathology, and clinical course of T1D, there are still knowledge gaps and opportunities for improving understanding of its pathogenesis. Emerging therapies are being developed to treat or prevent T1D.
JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Medicine, General & Internal
Barbara H. Braffett, Ionut Bebu, Laure El Ghormli, Catherine C. Cowie, William Sivitz, Rodica Pop-Busui, Mary E. Larkin, Rose A. Gubitosi-Klug, David M. Nathan, John M. Lachin, Samuel Dagogo-Jack
Summary: Despite a more favorable cardiometabolic risk factor profile, women with type 1 diabetes did not have a significantly lower cardiovascular disease event burden than men, suggesting a greater clinical impact of cardiometabolic risk factors in women with diabetes. These findings call for conscientious optimization of the control of cardiovascular disease risk factors in women with type 1 diabetes.
Article
Medicine, General & Internal
Chia-Hung Lin, Fu-Sung Lo, Yu-Yao Huang, Jui-Hung Sun, Szu-Tah Chen, Chang-Fu Kuo, Mei-Yun Hsieh, Sheng-Hwu Hsieh
Summary: This study from Taiwan suggests that individuals with type 1 diabetes and a family history of type 2 diabetes may have a higher risk of developing diabetes complications, highlighting the importance of close monitoring and management for these patients.
Article
Endocrinology & Metabolism
Aya Bardugo, Cole D. Bendor, Inbar Zucker, Miri Lutski, Tali Cukierman-Yaffe, Estela Derazne, Ofri Mosenzon, Dorit Tzur, Zivan Beer, Orit Pinhas-Hamiel, Michal Ben-Ami, Boris Fishman, Dana Ben-Ami Shor, Itamar Raz, Arnon Afek, Hertzel C. Gerstein, Hans-Ulrich Haring, Amir Tirosh, Zohar Levi, Gilad Twig
Summary: A study found that among normoglycemic adolescents, nonalcoholic fatty liver disease (NAFLD) was associated with an increased risk for type 2 diabetes, which may manifest before the age of 30.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Review
Endocrinology & Metabolism
Vikas S. Sridhar, Christine P. Limonte, Per-Henrik Groop, Hiddo J. L. Heerspink, Richard E. Pratley, Peter Rossing, Jay S. Skyler, David Z. I. Cherney
Summary: The current management of CKD in type 1 diabetes focuses on blood sugar control, inhibiting the renin-angiotensin system and optimizing risk factors. However, individuals with type 1 diabetes and CKD still face elevated risks for kidney and cardiovascular events. Novel therapies used in type 2 diabetes, such as sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide 1 receptor agonists, have shown potential kidney and heart protection. Applying these therapies to individuals with type 1 diabetes for the prevention of CKD is of great importance.
Article
Pediatrics
Sheryl Johnson, Simran Gupta, Eleanor Mackey, Kristy McCarron, Laura Fischer, Domonique Panton, Kofi Essel
Summary: This study explored the current barriers and management practices of primary care pediatric clinicians in dealing with patients with obesity. The results showed that while clinicians felt comfortable advising patients, they lacked confidence in addressing obesity and emphasized the need for more training in obesity management. Time constraint was identified as a barrier to care, and six themes emerged regarding clinician barriers, including limited time, perceived familial resistance, challenges with racial and ethnic concordance, perceived environmental barriers, limited knowledge of community resources, and inadequate collaborative support.
Article
Endocrinology & Metabolism
Michelle A. Van Name, Lauren G. Kanapka, Linda A. DiMeglio, Kellee M. Miller, Anastasia Albanese-O'Neill, Persis Commissariat, Sarah D. Corathers, Kara R. Harrington, Marisa E. Hilliard, Barbara J. Anderson, Jennifer C. Kelley, Lori M. Laffel, Sarah A. MacLeish, Brandon M. Nathan, William V. Tamborlane, R. Paul Wadwa, Steven M. Willi, Kristen M. Williams, Kupper A. Wintergerst, Stephanie Woerner, Jenise C. Wong, Daniel J. DeSalvo
Summary: This study examined the durability of continuous glucose monitoring (CGM) coupled with a family behavioral intervention (FBI) to improve glycemia in young children with type 1 diabetes (T1D). The results showed that CGM technology could reduce the incidence of hypoglycemia, but had limited effect on hyperglycemia.
JOURNAL OF DIABETES SCIENCE AND TECHNOLOGY
(2023)
Article
Medicine, Research & Experimental
Maeve B. O'Donnell, Samantha R. Scott, Britney M. Ellisor, Viena T. Cao, Chuan Zhou, Miranda C. Bradford, Catherine Pihoker, Daniel J. DeSalvo, Faisal S. Malik, Marisa E. Hilliard, Abby R. Rosenberg, Joyce P. Yi-Frazier
Summary: The PRISM program is a skills-based intervention aimed at promoting resilience among adolescents with T1D and elevated diabetes distress. This randomized controlled trial seeks to assess the impact of PRISM on glycemic outcomes, diabetes distress, resilience, self-reported adherence, and quality of life. The study aims to provide rigorous evidence and data regarding the effectiveness of this novel intervention and its potential to improve outcomes for this high-risk group.
CONTEMPORARY CLINICAL TRIALS
(2023)
Article
Endocrinology & Metabolism
Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Jose Leon, Sarah K. Lyons, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Deborah Young-Hyman, Robert A. Gabbay
Article
Endocrinology & Metabolism
Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Jose Leon, Sarah K. Lyons, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Robert A. Gabbay
Article
Endocrinology & Metabolism
Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Sandeep R. Das, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Mikhail Kosiborod, Jose Leon, Sarah K. Lyons, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Robert A. Gabbay
Article
Endocrinology & Metabolism
Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Christopher H. Gibbons, John M. Giurini, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Jose Leon, Sarah K. Lyons, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Jennifer K. Sun, Robert A. Gabbay
Article
Endocrinology & Metabolism
Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Jose Leon, Sarah K. Lyons, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Robert A. Gabbay
Article
Endocrinology & Metabolism
Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Jose Leon, Sarah K. Lyons, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Robert A. Gabbay
Article
Endocrinology & Metabolism
Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Jose Leon, Sarah K. Lyons, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Robert A. Gabbay
Editorial Material
Endocrinology & Metabolism
Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Kenneth Cusi, Sandeep R. Das, Christopher H. Gibbons, John M. Giurini, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Mikhail Kosiborod, Jose Leon, Sarah K. Lyons, Lisa Murdock, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Jennifer K. Sun, Crystal C. Woodward, Deborah Young-Hyman, Robert A. Gabbay
Article
Endocrinology & Metabolism
Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Jose Leon, Sarah K. Lyons, Lisa Murdock, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Crystal C. Woodward, Robert A. Gabbay
Article
Endocrinology & Metabolism
Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Jose Leon, Sarah K. Lyons, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Robert A. Gabbay
Summary: The American Diabetes Association (ADA) Standards of Care provide clinical practice recommendations, treatment goals, and tools for evaluating quality of care in diabetes. These standards are updated annually by a multidisciplinary expert committee and can be accessed on the ADA's website. Readers are also invited to provide feedback on the standards.
Article
Endocrinology & Metabolism
Persis A. Commissariat, Linda G. DiMeglio, Lauren M. Kanapka, Lori M. Laffel, Kellee J. Miller, Barbara E. Anderson, Marisa Hilliard
Summary: The study found that providing continuous glucose monitoring and family behavioral intervention can reduce stress for parents of young children with type 1 diabetes. In a 52-week trial, the group using continuous glucose monitoring with family behavioral intervention and the group using continuous glucose monitoring alone reported improvements in diabetes burden, fear of hypoglycemia, and technology satisfaction. The group that transitioned from blood glucose monitoring to continuous glucose monitoring with family behavioral intervention also showed similar results between 26 and 52 weeks.
Article
Endocrinology & Metabolism
Nuha A. ElSayed, Grazia Aleppo, Vanita R. Aroda, Raveendhara R. Bannuru, Florence M. Brown, Dennis Bruemmer, Billy S. Collins, Marisa E. Hilliard, Diana Isaacs, Eric L. Johnson, Scott Kahan, Kamlesh Khunti, Jose Leon, Sarah K. Lyons, Mary Lou Perry, Priya Prahalad, Richard E. Pratley, Jane Jeffrie Seley, Robert C. Stanton, Robert A. Gabbay