Article
Medicine, Research & Experimental
Enmin Xie, Zixiang Ye, Yaxin Wu, Xuecheng Zhao, Yike Li, Nan Shen, Xiaochun Guo, Yanxiang Gao, Jingang Zheng
Summary: The TyG index is significantly associated with coronary artery disease severity and mortality in patients on dialysis, highlighting its clinical importance in assessing disease severity and risk stratification.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2023)
Review
Cardiac & Cardiovascular Systems
Shichu Liang, Cui Wang, Jing Zhang, Zhiyue Liu, Yanlin Bai, Zhonglan Chen, He Huang, Yong He
Summary: This study conducted a systematic review and meta-analysis to summarize the relationship between the TyG index and the risk, severity, and prognosis of coronary artery disease (CAD). The results showed that patients with higher TyG index levels had a higher risk of CAD, more severe coronary artery lesions, and worse prognosis.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Jianqi Zhao, Hongxuan Fan, Ting Wang, Bing Yu, Shaobin Mao, Xun Wang, Wenjing Zhang, Leigang Wang, Yao Zhang, Zhaoyu Ren, Bin Liang
Summary: The TyG index is positively correlated with CHD risk in NAFLD patients and reflects the severity of coronary atherosclerosis.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ang Gao, Jinxing Liu, Chengping Hu, Yan Liu, Yong Zhu, Hongya Han, Yujie Zhou, Yingxin Zhao
Summary: The study demonstrated a strong association between the TyG index and impaired collateralization in CAD patients with CTO lesions. Higher TyG index values were significantly correlated with an increased risk of less developed collateralization even after adjusting for confounding factors. The risk assessment performance of the TyG index for impaired collateralization was found to be better than other single metabolic abnormality indicators.
LIPIDS IN HEALTH AND DISEASE
(2021)
Article
Nutrition & Dietetics
Zeinab Ghorbani, Seyedeh Nooshan Mirmohammadali, Nargeskhatoon Shoaibinobarian, Sara K. Rosenkranz, Samira Arami, Azita Hekmatdoost, Marjan Mahdavi-Roshan
Summary: This study found positive associations between surrogate markers of insulin resistance (TyG and TyG-BMI) and the risk of hyperuricemia in patients with coronary artery disease (CAD). However, due to the cross-sectional design of the study, the sensitivity and specificity of these markers in diagnosing insulin resistance and hyperuricemia could not be determined. Further research is needed to confirm these findings and determine the diagnostic value of these markers.
FRONTIERS IN NUTRITION
(2023)
Article
Endocrinology & Metabolism
Yu Zhang, Ruiling Wang, Xuelian Fu, Haiyan Song
Summary: This study is the first to demonstrate the association between TyG-BMI index and CAD severity. The TyG index, TyG-BMI index, TG/HDL-C ratio, and METS-IR can serve as valuable predictors of CAD severity.
DIABETOLOGY & METABOLIC SYNDROME
(2022)
Article
Cardiac & Cardiovascular Systems
Enmin Xie, Zixiang Ye, Yaxin Wu, Xuecheng Zhao, Yike Li, Nan Shen, Yanxiang Gao, Jingang Zheng
Summary: The triglyceride-glucose (TyG) index may serve as a valuable and dependable indicator of major adverse cardiovascular events (MACE) risk in individuals with end-stage renal disease (ESRD) and coronary artery disease (CAD), indicating its potential significance in enhancing risk categorization in clinical settings.
CARDIOVASCULAR DIABETOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Jin-Wen Luo, Wen-Hui Duan, Yan-Qiao Yu, Lei Song, Da-Zhuo Shi
Summary: The triglyceride-glucose index (TyG) is significantly associated with adverse cardiovascular events in patients with coronary artery disease (CAD), with a higher risk observed in the high TyG group compared to the low TyG group. Secondary outcomes also showed increased risks of myocardial infarction, stroke, and revascularization in the high TyG group.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Peripheral Vascular Disease
Yihai Liu, Lei Chang, Mingyue Wu, Biao Xu, Lina Kang
Summary: This study found that higher TyG index was significantly associated with higher risk of PAD, which could be a marker for PAD.
Article
Cardiac & Cardiovascular Systems
Jing-Wei Gao, Qing-Yun Hao, Ming Gao, Kun Zhang, Xiong-Zhi Li, Jing-Feng Wang, Dominique A. Vuitton, Shao-Ling Zhang, Pin-Ming Liu
Summary: The study found a significant association between TyG index and the risk of incident PAD; tracking the trajectories of TyG index over the long term can help identify individuals at high risk for PAD.
CARDIOVASCULAR DIABETOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Li-Chan Tao, Jia-ni Xu, Ting-ting Wang, Fei Hua, Jian-Jun Li
Summary: This review summarizes the history of the use of the TyG index as a surrogate marker for insulin resistance (IR) and explores its application value in various types of cardiovascular disease (CVD), as well as the potential limitations of using this index as a predictor for cardiovascular events. The aim is to provide more extensive and precise supporting evidence to improve its application value in CVD.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Zhenguo Wu, Li Liu, Weiwei Wang, Huiliang Cui, Yerui Zhang, Jiechang Xu, Wencheng Zhang, Tengfei Zheng, Jianmin Yang
Summary: The TyG index is an independent predictor of major adverse cardiovascular events (MACE) in patients with premature coronary artery disease (PCAD), and it can be used for risk stratification and early intervention.
CARDIOVASCULAR DIABETOLOGY
(2022)
Review
Endocrinology & Metabolism
Wei-Ting Chang, Chien-Cheng Liu, Yen-Ta Huang, Jheng-Yan Wu, Wen-Wen Tsai, Kuo-Chuan Hung, I-Wen Chen, Ping-Hsun Feng
Summary: This meta-analysis evaluated the diagnostic value of the triglyceride-glucose (TyG) index in predicting contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI). The results demonstrated a significant correlation between the TyG index and the risk of CIN, with moderate diagnostic accuracy. However, the heterogeneity between studies suggests that the TyG index should not be used alone for CIN screening. Further large-scale studies are needed to validate TyG cutoffs and determine its optimal incorporation into current risk prediction models.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Shalaimaiti Shali, Lingfeng Luo, Kang Yao, Xiangdong Sun, Hongyi Wu, Shuning Zhang, Lili Xu, Wei Gao, Jianxuan Li, Juying Qian, Yan Zheng, Yuxiang Dai, Junbo Ge, GRAND investigators
Summary: The study aimed to evaluate the usefulness of the triglyceride-glucose (TyG) index in identifying young coronary artery disease (CAD) patients and predicting their risk of developing target lesion failure (TLF). The results showed that the TyG index was positively associated with the prevalence of CAD and incident TLF.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Xiang Wang, Wei Xu, Qirui Song, Zinan Zhao, Xuyang Meng, Chenxi Xia, Yibo Xie, Chenguang Yang, Pengfei Jin, Fang Wang
Summary: This study found that an increased TyG index was associated with a higher risk of multi-vessel CAD. The TyG index could be a valuable predictor of CAD severity, especially for individuals with pre-DM.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Dagmar F. Hernandez-Suarez, Lorenzo Azzalini, Francesco Moroni, Joao Eduardo Tinoco de Paula, Pablo Lamelas, Carlos M. Campos, Marcelo Harada Ribeiro, Evandro Martins Filho, Felix Damas de los Santos, Lucio Padilla, Marco Alcantara-Melendez, Marcelo A. Abud, Israel A. Almodovar-Rivera, Marcia Moura Schmidt, Mauro Echavarria, Antonio Carlos Botelho, Valentin Del Rio, Alexandre Quadros, Ricardo Santiago
Summary: In a multi-center CTO-PCI registry in Latin America, patients with prior CABG had more comorbidities, higher anatomical complexity, lower success rates, but similar in-hospital adverse event rates compared to patients without prior CABG surgery.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Nutrition & Dietetics
Julia L. dos Santos, Vera L. Portal, Melissa M. Markoski, Alexandre S. de Quadros, Angela Bersch-Ferreira, Aline Marcadenti
Summary: The study found that adding pecan nuts or extra-virgin olive oil to a healthy diet did not significantly affect glycemic and anthropometric profiles in stable CAD patients after a 12-week clinical trial. However, the pecan nut group showed improved diet quality compared to the other groups. Further research is needed to explore the impact of dietary interventions on secondary cardiovascular prevention.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
Giuseppe De Luca, Magdy Algowhary, Berat Uguz, Dinaldo C. Oliveira, Vladimir Ganyukov, Zan Zimbakov, Miha Cercek, Lisette Okkels Jensen, Poay Huan Loh, Lucian Calmac, Gerard Roura-Ferrer, Alexandre Quadros, Marek Milewski, Fortunato Scotto di Uccio, Clemens von Birgelen, Francesco Versaci, Jurrien Ten Berg, Gianni Casella, Aaron Sung Lung Wong, Petr Kala, Jose Luis Diez Gil, Xavier Carrillo, Maurits Theodoor Dirksen, Victor Manuel Becerra-Munoz, Michael Kang-yin Lee, Dafsah A. Juzar, Rodrigo de Moura Joaquim, Roberto Paladino, Davor Milicic, Periklis Davlouros, Nikola Bakraceski, Filippo Zilio, Luca Donazzan, Adriaan O. Kraaijeveld, Gennaro Galasso, Arpad Lux, Lucia Marinucci, Vincenzo Guiducci, Maurizio Menichelli, Alessandra Scoccia, Aylin Yamac, Kadir Ugur Mert, Xacobe Flores Rios, Tomas Kovarnik, Michal Kidawa, Jose Moreu, Vincent Flavien, Enrico Fabris, Inigo Lozano Martinez-Luengas, Marco Boccalatte, Francisco Bosa Ojeda, Carlos Arellano-Serrano, Gianluca Caiazzo, Giuseppe Cirrincione, Hsien-Li Kao, Juan Sanchis Fores, Luigi Vignali, Helder Pereira, Stephane Manzo-Silberman, Santiago Ordonez, Alev Arat Ozkan, Bruno Scheller, Heidi Lehtola, Rui Teles, Christos Mantis, Antti Ylitalo, Joao Antonio Brum Silveira, Rodrigo Zoni, Ivan Bessonov, Stefano Savonitto, George Kochiadakis, Dimitrios Alexopoulos, Carlos Uribe, John Kanakakis, Benjamin Faurie, Gabriele Gabrielli, Alejandro Gutierrez, Juan Pablo Bachini, Alex Rocha, Franckie C. C. Tam, Alfredo Rodriguez, Antonia Lukito, Veauthyelau Saint-Joy, Gustavo Pessah, Bernardino Tuccillo, Giuliana Cortese, Guido Parodi, Mohamed Abed Bouraghda, Elvin Kedhi, Pablo Lamelas, Harry Suryapranata, Matteo Nardin, Monica Verdoia
Summary: The COVID-19 pandemic significantly impacted percutaneous revascularisation for STEMI, with a 16% reduction in PPCI procedures in 2020 compared to 2019, especially among older patients. There were longer delays to treatment, resulting in increased in-hospital and 30-day mortality during the pandemic.
Review
Endocrinology & Metabolism
Marcus Vinicius Bolivar Malachias, Magnus Olof Wijkman, Marcello Casaccia Bertoluci
Summary: Existing risk prediction scores may be inaccurate in patients with Type 2 Diabetes Mellitus (T2DM), but measurement of natriuretic peptides, particularly NT-proBNP, can be an effective tool for risk stratification. NT-proBNP improves outcome prediction and has similar or even superior ability compared to multivariate risk models in predicting death and cardiovascular events in individuals with T2DM.
DIABETOLOGY & METABOLIC SYNDROME
(2022)
Article
Endocrinology & Metabolism
Joao Roberto de Sa, Erika Bevilaqua Rangel, Luis Henrique Canani, Andrea Carla Bauer, Gustavo Monteiro Escott, Themis Zelmanovitz, Marcello Casaccia Bertoluci, Sandra Pinho Silveiro
Summary: The review on Diabetic Kidney Disease by SBD provides evidence-based guidelines for management with recommendations categorized by levels of evidence and degrees of agreement from panelists. Intensive glycemic control, blood pressure management, and the use of specific medications are essential for preventing advanced stages of DKD.
DIABETOLOGY & METABOLIC SYNDROME
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Fabio Sandoli de Brito Jr, Rogerio Sarmento-Leite, George Dangas
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Endocrinology & Metabolism
Marcio Mossmann, Marco Vugman Wainstein, Stefani Mariani, Guilherme Pinheiro Machado, Gustavo Neves de Araujo, Michael Andrades, Sandro Cadaval Goncalves, Marcello Casaccia Bertoluci
Summary: The study found that in high-risk patients, IL-6 levels exceeding 0.44 pg/mL before elective coronary angiography were associated with a poorer prognosis.
DIABETOLOGY & METABOLIC SYNDROME
(2022)
Article
Obstetrics & Gynecology
Roberta de Padua Borges, Georgia Oliveira Avila, Amanda Cunha Ritter, Janine Alessi, Angela Jacob Reichelt, Maria Lucia da Rocha Oppermann, Gabriela Heiden Telo, Beatriz D. Schaan
Summary: This study evaluated the indirect effects of the COVID-19 pandemic on the care of women with pregnancies complicated by gestational or pre-existing diabetes, and their maternal-fetal outcomes. The study found that despite the impact of the pandemic on the economy, society, and structure, parameters of maternal care were similar, diabetes control improved, and neonatal hypoglycemia and SGA rates were lower among pregnant women with diabetes during the pandemic.
JOURNAL OF PERINATAL MEDICINE
(2023)
Letter
Medicine, General & Internal
Fernando Korn Malerbi, Marcio Krakauer, Beatriz Schaan
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA
(2022)
Review
Endocrinology & Metabolism
William Valadares Campos Pereira, Denise Maria Martins Vancea, Ricardo de Andrade Oliveira, Yuri Galeno Pinheiro Chaves de Freitas, Rodrigo Nunes Lamounier, Wellington S. S. Silva Junior, Andrea Messias Britto Fioretti, Clayton Luiz Dornelles Macedo, Marcello Casaccia Bertoluci, Roberto Luis Zagury
Summary: For individuals diagnosed with diabetes mellitus, properly oriented physical exercises bring significant benefits to their health. The individualization of exercise routines is important for therapeutic success. This review provides guidance on physical activities and exercises for individuals with type 1 and 2 diabetes based on scientific evidence.
DIABETOLOGY & METABOLIC SYNDROME
(2023)
Editorial Material
Endocrinology & Metabolism
Beatriz D. Schaan
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2023)
Article
Public, Environmental & Occupational Health
Augusto Cesar Ferreira De Moraes, Vanessa Cassia Medeiros-Oliveira, Katie Burford, Beatriz D. Schaan, Katia Bloch, Kenia Mara Baiocchi de Carvalho, Felipe Vogt Cureau, Marcus Vinicius Nascimento-Ferreira
Summary: This study aimed to investigate the associations between movement behaviors, abdominal obesity, and inflammatory biomarkers in adolescents, as well as the mediating role of waist circumference. The results showed a negative association between sleep duration and inflammatory biomarkers, and waist circumference partially mediated this association. Therefore, maintaining healthy sleep habits can have positive implications for reducing waist circumference and inflammatory indicators in adolescents.
JOURNAL OF PHYSICAL ACTIVITY & HEALTH
(2023)
Review
Endocrinology & Metabolism
Aline Chagastelles Pinto de Macedo, Camila Wohlgemuth Schaan, Patricia Martins Bock, Mariana Brutto de Pinto, Cintia Ehlers Botton, Daniel Umpierre, Beatriz D. Schaan
Summary: This systematic review and meta-analysis found that individuals with type 2 diabetes had lower cardiorespiratory fitness compared to individuals without diabetes, as demonstrated by lower maximal oxygen consumption (VO(2)max) and smaller walking distance in the 6-minute walk test. However, the quality of the studies included in the analysis was low.
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2023)
Article
Public, Environmental & Occupational Health
Amanda Veiga Cheuiche, Felipe Vogt Cureau, Mariana Migliavacca Madalosso, Gabriela Heiden Telo, Beatriz D. Schaan
Summary: The study found differences in the mean height among adolescents from the five regions of Brazil, which were influenced by socioeconomic status and nutritional factors. Especially in older age groups, factors such as physical activity, maternal education level, protein intake, and body mass index had a positive impact on normal growth.
CADERNOS DE SAUDE PUBLICA
(2022)
Article
Endocrinology & Metabolism
Isadora Nunes Erthal, Janine Alessi, Julia Belato Teixeira, Eduarda Herscovitz Jaeger, Giovana Berger de Oliveira, Gabriela D. L. G. Scherer, Taise Rosa de Carvalho, Beatriz D. Schaan, Gabriela H. Telo
Summary: This longitudinal study followed diabetes patients in Southern Brazil over an 18-month period during the COVID-19 pandemic. Findings showed a mix of worsened and improved lifestyle aspects among patients, with factors like age, diabetes duration, and emotional eating being associated with worsening food quality and sleep quality during the pandemic. Clinical features related to worsening in food and sleep quality provide new insights for prioritizing actions in crisis situations.
ACTA DIABETOLOGICA
(2022)