期刊
CELL ADHESION & MIGRATION
卷 7, 期 1, 页码 82-89出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/cam.22480
关键词
laminin; retina; blood vessels; angiogenesis; astrocytes; development
类别
资金
- Knight's Templar Eye Foundation
- National Institute of Health [EY-09357]
The mechanisms controlling vascular development, both normal and pathological, are not yet fully understood. Many diseases, including cancer and diabetic retinopathy, involve abnormal blood vessel formation. Therefore, increasing knowledge of these mechanisms may help develop novel therapeutic targets. The identification of novel proteins or cells involved in this process would be particularly useful. The retina is an ideal model for studying vascular development because it is easy to access, particularly in rodents where this process occurs post-natally. Recent studies have suggested potential roles for laminin chains in vascular development of the retina. This review will provide an overview of these studies, demonstrating the importance of further research into the involvement of laminins in retinal blood vessel formation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据