Enhancing integrin function by VEGF/neuropilin signaling

Neuropilin-1Stimulates Tumor Growth by Increasing Fibronectin Fibril Assembly in the Tumor Microenvironment

(2012) Usman Yaqoob et al.   CANCER RESEARCH

Neuropilin-2 regulates  6 1 integrin in the formation of focal adhesions and signaling

(2012) H. L. Goel et al.   JOURNAL OF CELL SCIENCE

Autocrine VEGF–VEGFR2–Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

(2012) Petra Hamerlik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD49f Enhances Multipotency and Maintains Stemness Through the Direct Regulation of OCT4 and SOX2

(2012) Kyung-Rok Yu et al.   STEM CELLS

VEGF/Neuropilin-2 Regulation of Bmi-1 and Consequent Repression of IGF-IR Define a Novel Mechanism of Aggressive Prostate Cancer

(2012) Hira Lal Goel et al.   Cancer Discovery

Integrin Targeted Therapeutics

(2012) Melissa Millard et al.   Theranostics

Cooperation Between Integrins and Growth Factor Receptors in Signaling and Endocytosis

(2011) Johanna Ivaska et al.   Annual Review of Cell and Developmental Biology

Regulation of Integrin Activation

(2011) Chungho Kim et al.   Annual Review of Cell and Developmental Biology

Mechanisms of integrin activation and trafficking

(2011) Coert Margadant et al.   CURRENT OPINION IN CELL BIOLOGY

Integrin inside-out signaling and the immunological synapse

(2011) Timothy A Springer et al.   CURRENT OPINION IN CELL BIOLOGY

Neuropilin-2 promotes branching morphogenesis in the mouse mammary gland

(2011) H. L. Goel et al.   DEVELOPMENT

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

(2011) Benjamin Beck et al.   NATURE

Overexpression of VEGF189 in breast cancer cells induces apoptosis via NRP1 under stress conditions

(2011) Nadejda Vintonenko et al.   Cell Adhesion & Migration

ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading

(2010) Paul Mak et al.   CANCER CELL

Autocrine VEGF Signaling Synergizes with EGFR in Tumor Cells to Promote Epithelial Cancer Development

(2010) Beate M. Lichtenberger et al.   CELL

Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content

(2010) Salvatore Pece et al.   CELL

Integrin Alpha 6 Regulates Glioblastoma Stem Cells

(2010) Justin D. Lathia et al.   Cell Stem Cell

Bmi-1 Is a Crucial Regulator of Prostate Stem Cell Self-Renewal and Malignant Transformation

(2010) Rita U. Lukacs et al.   Cell Stem Cell

NPA motifs play a key role in plasma membrane targeting of aquaporin-4

(2010) Xin-Gang Guan et al.   IUBMB LIFE

Neuropilin-2 acts as a modulator of Sema3A-dependent glioma cell migration

(2010) Cécile Nasarre et al.   Cell Adhesion & Migration

Neuropilin-2 expression in breast cancer: correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression

(2009) Hironao Yasuoka et al.   BMC CANCER

Vascular Endothelial Growth Factor-C Protects Prostate Cancer Cells from Oxidative Stress by the Activation of Mammalian Target of Rapamycin Complex-2 and AKT-1

(2009) M. H. Muders et al.   CANCER RESEARCH

Neuropilins in Tumor Biology

(2009) A. Bagri et al.   CLINICAL CANCER RESEARCH

Role of Class 3 Semaphorins and Their Receptors in Tumor Growth and Angiogenesis

(2009) P. Gaur et al.   CLINICAL CANCER RESEARCH

αvβ3 Integrin Limits the Contribution of Neuropilin-1 to Vascular Endothelial Growth Factor-induced Angiogenesis

(2009) Stephen D. Robinson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrins: masters and slaves of endocytic transport

(2009) Patrick T. Caswell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells

(2009) Donatella Valdembri et al.   PLOS BIOLOGY

Autocrine semaphorin3A stimulates alpha2 beta1 integrin expression/function in breast tumor cells

(2008) Hongjie Pan et al.   BREAST CANCER RESEARCH AND TREATMENT

Blocking Neuropilin-2 Function Inhibits Tumor Cell Metastasis

(2008) Maresa Caunt et al.   CANCER CELL

Neuropilin-1 Upholds Dedifferentiation and Propagation Phenotypes of Renal Cell Carcinoma Cells by Activating Akt and Sonic Hedgehog Axes

(2008) Ying Cao et al.   CANCER RESEARCH

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

(2008) Valeria Facchinetti et al.   EMBO JOURNAL

Neuropilins: a versatile partner of extracellular molecules that regulate development and disease

(2008) Katarzyna Adela Uniewicz   Frontiers in Bioscience-Landmark

Metabolic Stress Induces the Lysosomal Degradation of Neuropilin-1 but Not Neuropilin-2

(2008) Donggoo Bae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic Targeting of Neuropilin-2 on Colorectal Carcinoma Cells Implanted in the Murine Liver

(2008) M. J. Gray et al.   JNCI-Journal of the National Cancer Institute

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS

Overexpression of Vascular Endothelial Growth Factor 189 in Breast Cancer Cells Leads to Delayed Tumor Uptake with Dilated Intratumoral Vessels

(2007) Marie-Astrid Hervé et al.   AMERICAN JOURNAL OF PATHOLOGY