Article
Oncology
Frederik Knude Palshof, Charlotte Lanng, Niels Kroman, Cemil Benian, Ilse Vejborg, Anne Bak, Maj-Lis Talman, Eva Balslev, Tove Filtenborg Tvedskov
Summary: The study found that MRI was more specific than US in predicting pCR in breast cancer patients receiving NACT, but not specific enough to be a valid predictor for omitting surgery. MRI should be preferred for future studies on predicting pCR in NACT patients.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Marina Sekacheva, Alexander Boroda, Anastasia Fatyanova, Alexander Rozhkov, Nikolai Bagmet
Summary: The blind clinical study aimed to evaluate the novel in-vitro diagnostic chemiluminescent CLIA-CA-62 assay for early-stage breast cancer detection. The results showed that the overall sensitivity of CLIA-CA-62 for breast cancer was 92% (100% for DCIS), decreasing in invasive stages (Stage I=97%, Stage II=85%, and Stage III=83%). This suggests that CLIA-CA-62 could be a useful supplement to current mammography screening and other imaging methods, improving the diagnostic sensitivity for DCIS and Stage I breast cancer.
FRONTIERS IN ONCOLOGY
(2023)
Article
Surgery
Jiarui Nangong, Zhongquan Cheng, Leyi Yu, Xiaodan Zheng, Guoqian Ding
Summary: This study described the clinical imaging and pathological features of invasive micropapillary breast carcinoma (IMPC), including breast mammography, sonography, MRI, and molecular imaging. The findings suggested that these imaging features were helpful for diagnosing and evaluating the invasiveness and lymph node metastasis of the disease.
FRONTIERS IN SURGERY
(2022)
Article
Multidisciplinary Sciences
Wenya Du, Lin Zhang, Emma Suh, Dabin Lin, Colin Marcus, Lara Ozkan, Avani Ahuja, Sara Fernandez, Ikra Iftekhar Shuvo, David Sadat, Weiguo Liu, Fei Li, Anantha P. Chandrakasan, Tolga Ozmen, Canan Dagdeviren
Summary: Researchers developed a wearable, conformable ultrasound breast patch (cUSBr-Patch) that allows standardized and reproducible image acquisition over the entire breast, reducing reliance on operator training and transducer compression. The patch, inspired by nature's honeycomb shape and guided by a user-friendly tracker, enables large-area, deep scanning, and multiangle breast imaging. In vitro studies and clinical trials demonstrated that the piezoelectric crystal-based array (Yb/Bi-PIN-PMN-PT) exhibited sufficient contrast resolution (approximately 3 dB) and axial/lateral resolutions of 0.25/1.0 mm at a depth of 30 mm, enabling the observation of small cysts (approximately 0.3 cm) in the breast. This research introduces a novel ultrasound technology for noninvasive real-time tracking of soft tissue dynamic changes.
Article
Radiology, Nuclear Medicine & Medical Imaging
Man-Qi Zhang, Yu Du, Hai-Ling Zha, Xin-Pei Liu, Meng-Jun Cai, Zhi-Hui Chen, Rui Chen, Jue Wang, Shou-Ju Wang, Jiu-Lou Zhang, Cui-Ying Li
Summary: This study aims to predict advanced breast cancers sensitive to neoadjuvant chemotherapy (NAC) through constructing a combined radiomics model based on pre-treatment ultrasound. The radiomics nomogram of ultrasound (RU) showed superior performance compared to clinical model and radiomics signature alone in identifying Grade 4-5 patients.
BRITISH JOURNAL OF RADIOLOGY
(2022)
Article
Health Care Sciences & Services
Melania Costantini, Rino Aldo Montella, Maria Paola Fadda, Vincenzo Tondolo, Gianluca Franceschini, Sonia Bove, Giorgia Garganese, Pierluigi Maria Rinaldi
Summary: Invasive lobular carcinoma is the second most common histologic form of breast cancer, with an insidious proliferative pattern making it difficult to diagnose clinically and radiologically. Breast MR is considered the most accurate imaging modality for detecting and staging invasive lobular carcinoma, while CESM is a promising new diagnostic method that can accurately detect malignant breast lesions similar to breast MR and has potential for preoperative surgical planning.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Review
Health Care Sciences & Services
Luca Nicosia, Giulia Gnocchi, Ilaria Gorini, Massimo Venturini, Federico Fontana, Filippo Pesapane, Ida Abiuso, Anna Carla Bozzini, Maria Pizzamiglio, Antuono Latronico, Francesca Abbate, Lorenza Meneghetti, Ottavia Battaglia, Giuseppe Pellegrino, Enrico Cassano
Summary: Breast cancer is the most common form of cancer in women and early diagnosis is crucial for saving lives. Mammography, a low-dose X-ray technique, is the most widely used diagnostic test for breast imaging. This historical review aims to provide a comprehensive understanding of the development of mammography and breast imaging, from clinical diagnosis to modern applications like contrast-enhanced mammography and artificial intelligence.
Article
Oncology
Cory Amanda Donovan, Cary S. Kaufman, Kari A. Thomas, Ayfer Kamali Polat, Marguerite Thomas, Bonnie Mack, Ariel Gilbert, Terry Sarantou
Summary: This study evaluates the timeliness of diagnostic imaging workup from screening mammogram to biopsy, based on aggregate data from 2005 to 2019. The results show that the time has decreased over the years, with patients on average receiving diagnostic imaging and biopsies within 1 week of abnormal results. However, there are variations in completion time among different regions and centers. Monitoring and comparing data can help improve quality in breast care.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Vivianne Freitas, Xuan Li, Yoav Amitai, Frederick Au, Supriya Kulkarni, Sandeep Ghai, Anna Marie Mulligan, Miluska Bromley, Timo Siepmann
Summary: This study retrospectively evaluated data of patients with newly diagnosed breast cancer from January 2008 to December 2010, and found that MRI screening of the contralateral breast improved long-term outcomes, with the most pronounced benefit observed in patients with larger primary tumor size and histologic grade III tumors.
Article
Radiology, Nuclear Medicine & Medical Imaging
Alistair Mackenzie, Emma L. Thomson, Melissa Mitchell, Premkumar Elangovan, Chantal van Ongeval, Lesley Cockmartin, Lucy M. Warren, Louise S. Wilkinson, Matthew G. Wallis, Rosalind M. Given-Wilson, David R. Dance, Kenneth C. Young
Summary: For calcification clusters, there were no significant differences in FoM or LDF. For masses, the FoM and LDF were significantly improved in the arms using DBT compared to DM alone. On average, both calcification clusters and masses were more visible on DBT than on DM and SM images.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Linda Appelman, Carmen C. N. Siebers, Peter T. M. Appelman, H. L. Shirley Go, Mireille J. M. Broeders, Marja C. J. van Oirsouw, Peter Bult, Ritse M. Mann
Summary: This study aimed to assess the feasibility of using targeted ultrasound alone as an imaging protocol for women with localized breast symptoms and the added value of digital breast tomosynthesis (DBT) in this setting. The results showed that ultrasound alone was comparable in accuracy to combined ultrasound and DBT as a breast imaging modality for focal breast complaints. DBT was able to detect malignant lesions not observed at the symptomatic site and incidental malignant findings in asymptomatic participants, with a cancer detection rate comparable to screening mammography.
Review
Radiology, Nuclear Medicine & Medical Imaging
Raymond J. Acciavatti, Su Hyun Lee, Beatriu Reig, Linda Moy, Emily F. Conant, Despina Kontos, Woo Kyung Moon
Summary: Breast density is an independent risk factor for breast cancer and can be assessed visually using digital mammography and tomosynthesis. In addition to density, textural complexity is also a measure of breast cancer risk. Other screening modalities like breast US and MRI offer independent risk measures as well.
Article
Radiology, Nuclear Medicine & Medical Imaging
Francesca Galati, Giuliana Moffa, Federica Pediconi
Summary: Breast cancer is a heterogeneous disease with various subtypes, and recent studies focus on using breast imaging to predict these subtypes and treatment response. The introduction of multiparametric studies and radiogenomics provides new insights for accurate diagnosis and treatment.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Nilgun Guldogan, Gul Esen, Yasemin Kayadibi, Fusun Taskin, Aysenur Oktay Alfatli, Fatma Nur Soylu Boy, Pinar Balci, Onur Bugdayci, Fatma Tokat, Tulin Ozturk, Mehtap Tunaci, Akif Enes Arikan
Summary: The study aims to determine the most common imaging features of adenoid cystic carcinoma (ACC) of the breast and review the literature. The findings show that ACC can present with various imaging characteristics, including round or oval shape, parallel orientation, isoechoic or hyperechoic appearance, high T2 signal, restricted diffusion, and homogeneous enhancement. Radiologists should be aware of these frequent findings for early diagnosis of ACC.
ACADEMIC RADIOLOGY
(2023)
Article
Multidisciplinary Sciences
Wen-Pei Wu, Chih-Yu Chen, Chih-Wei Lee, Hwa-Koon Wu, Shou-Tung Chen, Yu-Ting Wu, Ying-Jen Lin, Dar-Ren Chen, Shou-Jen Kuo, Hung-Wen Lai
Summary: The study demonstrated that adding pre-operative breast MRI to conventional imaging can increase the detection of contralateral synchronous breast cancer and reduce the occurrence of subsequent contralateral metachronous breast cancer during follow-up.