Review
Environmental Sciences
L. Luque-Garcia, A. Corrales, A. Lertxundi, S. Diaz, J. Ibarluzea
Summary: Exposure to greenness may have a positive impact on children's neuropsychological development and mental health. However, the current body of research exhibits heterogeneity and potential bias, indicating the need for further studies to confirm these associations and explore specific influencing factors.
ENVIRONMENTAL RESEARCH
(2022)
Review
Developmental Biology
Ana Filipa Ferreira, Maria Soares, Sandra Almeida Reis, Joao Ramalho-Santos, Ana Paula Sousa, Teresa Almeida-Santos
Summary: The effectiveness and safety of mitochondrial supplementation as a complementary treatment to assisted reproductive technologies are still controversial, with some studies showing improvement in certain outcomes while others did not. Concerns remain regarding the safety of mitochondria transfer, however, clinical studies have not reported congenital malformations, indicating relative safety. Further investigation is needed to better understand the impact of mitochondrial supplementation on oocyte competence.
Review
Multidisciplinary Sciences
Filomena Gomes, Shannon E. King, Diana Dallmann, Jenna Golan, Ana Carolina Feldenheimer da Silva, Kristen M. Hurley, Gilles Bergeron, Megan W. Bourassa, Saurabh Mehta
Summary: Prenatal micronutrient supplements are cost-effective in reducing nutritional deficiencies and adverse pregnancy outcomes, yet poor adherence remains a barrier. Education, monitoring, reminders, and other strategies can effectively improve adherence and potentially enhance the effects of prenatal supplementation on pregnancy and birth outcomes. Further high-quality studies are needed to guide policies and programs effectively.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2021)
Review
Nutrition & Dietetics
Slaheddine Delleli, Ibrahim Ouergui, Hamdi Messaoudi, Khaled Trabelsi, Jordan M. Glenn, Achraf Ammar, Hamdi Chtourou
Summary: This systematic review examined the acute and chronic ergogenic effects of dietary nitrate intake from beetroot on combat sports performance. The findings suggest that beetroot intake may improve oxidative metabolism and muscle force production in combat sports athletes, but these effects depend on various factors.
Review
Nutrition & Dietetics
Bahareh Barkhidarian, Lucas Roldos, Michele M. Iskandar, Ahmad Saedisomeolia, Stan Kubow
Summary: Probiotics have the potential to improve micronutrient status in healthy subjects, but studies show varying degrees of efficacy. Further clinical trials are needed to determine the most effective strains of probiotics, doses, and durations of interventions.
Review
Medicine, General & Internal
Fanji Qiu, Jinfeng Li, Kirsten Legerlotz
Summary: This systematic review and meta-analysis found that additional dietary supplementation during physiotherapeutic treatment can significantly improve the reduction in pain score, but it has no effect on functional outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Psychology, Multidisciplinary
Shahirose Sadrudin Premji, Gianella Santos Pana, Alexander Cuncannon, Paul E. Ronksley, Aliyah Dosani, K. Alix Hayden, Sharifa Lalani, Joseph Wangira Musana, Kiran Shaikh, Ilona S. Yim
Summary: This systematic review examines the association between prenatal allostatic load and preterm birth and finds mixed evidence. The study suggests that factors such as measurement methods and timing of allostatic load, study design, and socio-demographic characteristics may influence this association.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Nutrition & Dietetics
Alejandro Gomez-Bruton, Jorge Marin-Puyalto, Borja Muniz-Pardos, Angel Matute-Llorente, Juan Del Coso, Alba Gomez-Cabello, German Vicente-Rodriguez, Jose A. Casajus, Gabriel Lozano-Berges
Summary: This study reviewed the existing literature on the effects of caffeine supplementation on physical performance in adult female team-sport athletes. The meta-analysis results indicated that caffeine intake increased performance in specific team-sport skills, countermovement jump, total body impacts, and handgrip strength in women athletes. No effects were found on other performance variables such as perceived exertion, squat jumps, agility, and repeated sprint ability after fatigue.
Review
Nutrition & Dietetics
Kiran Kumar Gudivada, Ashish Kumar, Mariam Shariff, Sriram Sampath, Manu MK. Varma, Sumitra Sivakoti, Bhuvana Krishna
Summary: The study examined the effectiveness of antioxidant micronutrient supplementation in critically ill adult patients through experimental drugs, reviews, and analyses. The results indicate that AxM may reduce all-cause mortality, but the evidence is still insufficient. Secondary outcomes show that AxM is beneficial in some aspects for patients.
CLINICAL NUTRITION
(2021)
Review
Pediatrics
Mohan Kumar, Ranadip Chowdhury, Bireshwar Sinha, Ravi Prakash Upadhyay, Temsunaro Rongsen Chandola, Sarmila Mazumder, Sunita Taneja, Karen Edmond, Rajiv Bahl, Nita Bhandari, Usha Ramakrishnan, Juan A. Rivera, Sonia Tandon, Christopher P. Duggan, Enju Liu, Wafaie Fawzi, Karim Manji, Tarun Shankar Choudhary
Summary: There is insufficient evidence to determine whether supplementation with multiple micronutrients (MMN) has benefits or harms for preterm and low birth weight infants who are fed mother's own milk.
Review
Psychiatry
Vidhi Desai, Anita L. Kozyrskyj, Stuart Lau, Omolara Sanni, Liz Dennett, Jens Walter, Maria B. Ospina
Summary: This study aimed to evaluate the effectiveness of probiotics during pregnancy in reducing the risk of maternal mental health problems in the perinatal period. The results showed that probiotics have a certain effect in reducing anxiety symptoms, but their effectiveness in reducing depression symptoms is limited.
FRONTIERS IN PSYCHIATRY
(2021)
Review
Medicine, General & Internal
K. Shah, V. P. Varna, U. Sharma, D. Mavalankar
Summary: The evidence summary indicates that vitamin D supplementation is effective in reducing the severity of COVID-19, lowering the risk of mortality, and decreasing the need for intensive care and mechanical ventilation. However, more robust and larger trials are needed to further substantiate these findings.
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
(2022)
Review
Medicine, General & Internal
L. Telisinghe, M. Ruperez, M. Amofa-Sekyi, L. Mwenge, T. Mainga, R. Kumar, M. Hassan, L. H. Chaisson, F. Naufal, A. E. Shapiro, J. E. Golub, C. Miller, E. L. Corbett, R. M. Burke, P. MacPherson, R. J. Hayes, V Bond, C. Daneshvar, E. Klinkenberg, H. M. Ayles
Summary: Two systematic reviews were conducted to investigate the impact of TB screening on patient outcomes. Clinical review showed differences in diagnosis time and smear grade between screened and passively case found individuals; longitudinal studies found screening associated with lower case fatality. Economic review indicated lower total costs and prevalence of catastrophic costs in the screened group.
Review
Food Science & Technology
Yongjin Wang, Yandan Wang, Qayyum Shehzad, Yijia Su, Lirong Xu, Le Yu, Wei Zeng, Zhongxiang Fang, Gangcheng Wu, Wei Wei, Qingzhe Jin, Hui Zhang, Xingguo Wang
Summary: This systematic review and meta-analysis summarized available randomized controlled trials (RCTs) on the effects of omega-3 polyunsaturated fatty acids (PUFAs) supplementation on patients with metabolic syndrome (MetS) and related cardiovascular diseases (CVDs). The results showed that omega-3 PUFAs supplementation significantly reduced triglyceride, total cholesterol, blood pressure, inflammatory markers, and increased high-density lipoprotein levels.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Biochemistry & Molecular Biology
Cristina Rodriguez-Varela, Elena Labarta
Summary: CoQ10 supplementation may improve human oocyte quality and reproductive performance, but further clinical trials and molecular studies are needed for confirmation. Future research should focus on evaluating the impact of CoQ10 on oxidative stress status and mitochondrial function in human gametes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Correction
Clinical Neurology
Catherine Lebel, Anna MacKinnon, Mercedes Bagshawe, Lianne Tomfohr-Madsen, Gerald Giesbrecht
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Developmental Biology
Nicole Letourneau, Henry Ntanda, Victor L. Jong, Newsha Mahinpey, Gerald Giesbrecht, Kharah M. Ross
Summary: This study found that different kinds of prenatal maternal distress may affect infant immune epigenetic profiles, with late-pregnancy stressful life events and depressive symptoms potentially impacting methylation in immune signaling pathways, while early-pregnancy depressive symptoms may be involved in methylation of DNA transcription pathways in offspring. Exposure timing and kind of prenatal maternal distress could be important in predicting infant immune epigenetic profiles.
DEVELOPMENTAL PSYCHOBIOLOGY
(2021)
Review
Microbiology
Van A. Ortega, Emily M. Mercer, Gerald F. Giesbrecht, Marie-Claire Arrieta
Summary: This article discusses the biological and neuroendocrine networks regulating stress response, as well as the impact of gut microbiota on early-life development that may predispose individuals to various diseases later in life. Animal models have confirmed the influence of gut microbiota on HPA axis activity, stress reactivity, and brain development.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Nursing
Brenda M. Y. Leung, Cynthia Wandler, Tamara Pringsheim, Maria J. Santana
Summary: The study revealed that parents of children with complex mental healthcare needs in Alberta, Canada faced challenges in accessing healthcare services due to fragmented services, navigating a complex system, emotional distress, financial burdens, self-advocacy, and stigma. Parents offered solutions such as creating a one-stop shop service led by a navigator with a team approach to facilitate and support navigation across disciplines and sectors.
JOURNAL OF CHILD HEALTH CARE
(2022)
Article
Integrative & Complementary Medicine
Robin S. T. Ho, Fai Fai Ho, Jon Adams, Holger Cramer, Brenda Leung, Lesley Ward, Yan Zhang, Vincent C. H. Chung
Summary: By comparing the experiences of responders and non-responders to acupuncture, it is evident that responders value the empathy expression and trust-building with acupuncturists, and actively engage in lifestyle modifications, while non-responders focus more on reassurance regarding the safety of acupuncture and empowerment through peer support.
INTEGRATIVE MEDICINE RESEARCH
(2022)
Article
Medicine, General & Internal
Nicole Letourneau, Fariba Aghajafari, Rhonda C. Bell, Andrea J. Deane, Deborah Dewey, Catherine Field, Gerald Giesbrecht, Bonnie Kaplan, Brenda Leung, Henry Ntanda
Summary: The ongoing APrON study in Canada aims to investigate the relationship between maternal nutrient intake and mental health, pregnancy outcomes, and neurodevelopment and behavior of infants and children. The study has collected data from 2189 mothers, their children, and 1325 fathers from pregnancy to when the children are 3 years old. Key findings include the association between higher intake of selenium and omega-3 with a lower risk of perinatal depression, the recommendation of choline-rich foods and vitamin D supplementation for maternal and child health, and the impact of parental perinatal depression on family income and child behavior. Early adversity experienced by mothers predicts the likelihood of perinatal depression and anxiety, as well as behavioral problems in children.
Article
Neurosciences
Kathryn Y. Manning, Xiangyu Long, Dana Watts, Lianne Tomfohr-Madsen, Gerald F. Giesbrecht, Catherine Lebel
Summary: The study found that the COVID-19 pandemic may have long-term impacts on children and highlighted the important role of social support for pregnant individuals and developing infants. These findings provide timely evidence for informing clinical practice and policy, underscoring the importance of social support.
BIOLOGICAL PSYCHIATRY
(2022)
Article
Psychology, Developmental
Stacy Lu, Brenda M. Y. Leung, Alisha M. Bruton, Elizabeth Millington, E. Alexander, Kelsey Camden, Irene Hatsu, Jeanette M. Johnstone, L. Eugene Arnold
Summary: This study explores parents' experiences of living with a child with ADHD and how these experiences influence their perspectives on treatment preferences and priorities. Through interviews with parents, the impact of ADHD on families and the need for specific treatments were identified. The study found that parents desired family-centered, multimodal approaches to ADHD treatment.
CHILD CARE HEALTH AND DEVELOPMENT
(2022)
Article
Medicine, General & Internal
Brenda M. Y. Leung, Priya Srikanth, Barbara Gracious, Irene E. Hatsu, Gabriella Tost, Valerie Conrad, Jeanette M. Johnstone, L. Eugene Arnold
Summary: The Pediatric Adverse Event Rating Scale (PAERS) was used to measure adverse events in children with ADHD and emotional dysregulation in a multi-site clinical trial. The study found that a broad-spectrum multinutrient treatment resulted in greater improvement in anxiety symptoms compared to placebo, indicating it is a safe and effective intervention.
CURRENT MEDICAL RESEARCH AND OPINION
(2022)
Correction
Medicine, Research & Experimental
E. Bailin Xie, Kaeley M. Simpson, Kristin A. Reynolds, Ryan J. Giuliano, Jennifer L. P. Protudjer, Melanie Soderstrom, Shannon Sauer-Zavala, Gerald F. Giesbrecht, Catherine Lebel, Anna L. Mackinnon, Charlie Rioux, Lara Penner-Goeke, Makayla Freeman, Marlee R. Salisbury, Lianne Tomfohr-Madsen, Leslie E. Roos
Article
Medicine, Research & Experimental
E. Bailin Xie, Kaeley M. Simpson, Kristin A. Reynolds, Ryan J. Giuliano, Jennifer L. P. Protudjer, Melanie Soderstrom, Shannon Sauer-Zavala, Gerald F. Giesbrecht, Catherine Lebel, Anna L. Mackinnon, Charlie Rioux, Lara Penner-Goeke, Makayla Freeman, Marlee R. Salisbury, Lianne Tomfohr-Madsen, Leslie E. Roos
Summary: The prevalence of maternal depression and anxiety has increased during the COVID-19 pandemic. This study aims to evaluate the efficacy of the BEAM app-based program in reducing maternal depression symptoms, improving anxiety symptoms, parenting stress, family relationships, and mother and child functioning.
Article
Health Care Sciences & Services
Chinenye Nmanma Nwoke, Oluwagbohunmi A. Awosoga, Sheila McDonald, Glenda Bonifacio, Brenda M. Y. Leung
Summary: This quantitative cross-sectional study examined the views of African immigrant mothers in Alberta, Canada on perinatal mental health and screening acceptability. The study found that while these mothers had high knowledge of postnatal mental health, their knowledge of prenatal mental health and its impact on child development was limited. However, they showed a high acceptability towards universal perinatal mental health screening.
JMIR FORMATIVE RESEARCH
(2023)
Letter
Neurosciences
Irene E. Hatsu, Lisa M. Robinette, Jeanette M. Johnstone, Alisha M. Bruton, Brenda M. Y. Leung, Tonya Orchard, L. Eugene Arnold
NUTRITIONAL NEUROSCIENCE
(2023)
Article
Health Care Sciences & Services
Chinenye Nmanma Nwoke, Oluwagbohunmi A. Awosoga, Sheila McDonald, Glenda Bonifacio, Brenda M. Y. Leung
Summary: This study investigated the prevalence and associated factors of maternal depression and anxiety among African immigrant women in Alberta, Canada up to 2 years postpartum. The findings showed high rates of depression and anxiety in this population, and highlighted the importance of social support and community belonging in improving their mental health outcomes. Further research is needed to develop comprehensive health strategies and preventive measures for immigrant women, including increased access to family doctors.
JMIR FORMATIVE RESEARCH
(2023)
Article
Health Care Sciences & Services
Kamala Adhikari, Scott B. Patten, Alka B. Patel, Shahirose Premji, Suzanne Tough, Nicole Letourneau, Gerald Giesbrecht, Amy Metcalfe
Summary: Pooling data from pre-existing datasets can increase sample size and statistical power, but challenges may arise due to differences in how variables are measured. Harmonization strategies such as matching variables based on multiple features and processing partially matching variables under a common format can help generate comparable datasets. These strategies allow researchers to efficiently answer novel research questions that cannot be achieved using a single data source.
INTERNATIONAL JOURNAL OF POPULATION DATA SCIENCE (IJPDS)
(2021)
