Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production

Antihelminth Compound Niclosamide Downregulates Wnt Signaling and Elicits Antitumor Responses in Tumors with Activating APC Mutations

(2011) T. Osada et al.   CANCER RESEARCH

Loss of Caspase-2-dependent Apoptosis Induces Autophagy after Mitochondrial Oxidative Stress in Primary Cultures of Young Adult Cortical Neurons

(2011) Meenakshi Tiwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early Reduction of Serum-Free Light Chains Associates with Renal Recovery in Myeloma Kidney

(2011) C. A. Hutchison et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Melphalan and prednisone versus melphalan, prednisone and thalidomide for elderly and/or transplant ineligible patients with multiple myeloma: a meta-analysis

(2011) P Kapoor et al.   LEUKEMIA

The mammalian target of rapamycin pathway as a therapeutic target in multiple myeloma

(2011) Joseph Gera et al.   LEUKEMIA & LYMPHOMA

Renal Insufficiency and Failure

(2011) M. A. Dimopoulos et al.   Hematology-American Society of Hematology Education Program

Development of small molecules targeting the Wnt pathway for the treatment of colon cancer: a high-throughput screening approach

(2010) Wei Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF- B Pathway and Generation of Reactive Oxygen Species

(2010) Y. Jin et al.   CANCER RESEARCH

Target of Rapamycin Signaling in Leukemia and Lymphoma

(2010) C. Vu et al.   CLINICAL CANCER RESEARCH

Emerging therapies for the treatment of relapsed or refractory multiple myeloma

(2010) Meletios A. Dimopoulos et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Renal Impairment in Patients With Multiple Myeloma: A Consensus Statement on Behalf of the International Myeloma Working Group

(2010) Meletios A. Dimopoulos et al.   JOURNAL OF CLINICAL ONCOLOGY

NF-κB localization in multiple myeloma plasma cells and mesenchymal cells

(2010) Concetta Conticello et al.   LEUKEMIA RESEARCH

Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway

(2010) Xiaomei Ren et al.   ACS Medicinal Chemistry Letters

The Anti-Helminthic Niclosamide Inhibits Wnt/Frizzled1 Signaling

(2009) Minyong Chen et al.   BIOCHEMISTRY

Superoxide is the major reactive oxygen species regulating autophagy

(2009) Y Chen et al.   CELL DEATH AND DIFFERENTIATION

Detection of renal impairment as one specific comorbidity factor in multiple myeloma: multicenter study in 198 consecutive patients

(2009) Martina Kleber et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

The autonomous notch signal pathway is activated by baicalin and baicalein but is suppressed by niclosamide in K562 cells

(2009) An-Ming Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Patterns of Improved Survival in Patients With Multiple Myeloma in the Twenty-First Century: A Population-Based Study

(2009) Ingemar Turesson et al.   JOURNAL OF CLINICAL ONCOLOGY

Autologous Hematopoietic Stem-Cell Transplantation for Multiple Myeloma

(2009) Jean-Luc Harousseau et al.   NEW ENGLAND JOURNAL OF MEDICINE

Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling

(2009) Aruna D. Balgi et al.   PLoS One

Autophagy: Basic Principles and Relevance to Disease

(2008) Mondira Kundu et al.   Annual Review of Pathology-Mechanisms of Disease

In vitro trypanocidal activity of the anti-helminthic drug niclosamide

(2008) Karin Merschjohann et al.   EXPERIMENTAL PARASITOLOGY

International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders

(2008) A Dispenzieri et al.   LEUKEMIA