Article
Ophthalmology
Mark A. Bullimore, Samantha Sze -Yee Lee, Katrina L. Schmid, Jos J. Rozema, Nicolas Leveziel, Edward A. H. Mallen, Nina Jacobsen, Rafael Iribarren, Pavan K. Verkicharla, Jan Roelof Polling, Paul Chamberlain
Summary: Myopia can start and progress during childhood as well as during adulthood. This review aims to summarize the published data on myopia onset and progression in young adults aged 18 to 40, to characterize myopia in this age group, and to identify gaps in the current understanding.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Health Care Sciences & Services
Jieying Guan, Yingting Zhu, Qiuyue Hu, Shuyue Ma, Jingfeng Mu, Zhidong Li, Dong Fang, Xiaohua Zhuo, Haifei Guan, Qianhui Sun, Lin An, Shaochong Zhang, Peiwu Qin, Yehong Zhuo
Summary: This study determined the prevalence of high myopia in children and adolescents in southern China using real-world screening data and predicted its onset by studying the risk factors based on machine learning. High myopia had a high incidence in Guangdong Province, and age, uncorrected distance visual acuity, and spherical equivalents were predictive factors for its onset in schoolchildren.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Review
Medicine, General & Internal
Judith A. Smith, Ruben Burgos-Vargas
Summary: Some studies suggest that children with juvenile onset spondyloarthritis have a relatively poor outcome compared to other juvenile idiopathic arthritis categories, but new therapies such as TNF inhibitors offer hope for improving disease prognosis.
FRONTIERS IN MEDICINE
(2021)
Article
Ophthalmology
Kai Yip Choi, Henry Ho-Lung Chan
Summary: The study found an interaction between external environmental factors and intrinsic factors that may contribute to juvenile myopia progression. The relationship between intrinsic factors and myopia progression was stronger when the external risk was low, but was abolished when the external risk was high. External environmental factors significantly improved the variance in myopia progression explained by intrinsic factors.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Ophthalmology
Shikha Gupta, Abhishek Singh, Karthikeyan Mahalingam, Harathy Selvan, Prasad Gupta, Shivam Pandey, Bindu Somarajan, Viney Gupta
Summary: The study found that myopic patients with JOAG were 18 times more likely to experience glaucoma progression compared to mild or non-myopic individuals. Myopia progression was observed in 70% of patients during follow-up. Factors such as an increase in baseline vertical cup disc ratio, IOP fluctuations, and visual field decline were associated with an increase in myopia progression rate.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Ophthalmology
Franziska G. Rauscher, Mike Francke, Andreas Hiemisch, Wieland Kiess, Ralph Michael
Summary: This study aimed to identify risk factors for glaucoma progression in juvenile open angle glaucoma (JOAG) patients, particularly the association with myopia. The results showed that myopia was significantly associated with glaucoma progression, with myopic patients being 18 times more likely to progress compared to non-myopic patients. Additionally, baseline myopic refraction and faster myopia development were associated with JOAG progressors.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Pediatrics
Weiqun Wang, Fengyan Zhang, Shiao Yu, Nana Ma, Congcong Huang, Ming Wang, Li Wei, Junjie Zhang, Aicun Fu
Summary: This study aimed to evaluate the effectiveness of 0.01% atropine eye drops in preventing myopia shift and onset in premyopic children. A 13-month trial was conducted on 60 premyopic children aged 6-12 years. The results showed that 0.01% atropine significantly prevented myopic shift and axial elongation compared to the placebo group. The proportion of myopia onset and fast myopic shift was also significantly lower in the 0.01% atropine group. The study concludes that 0.01% atropine eye drops effectively prevent myopia shift, axial elongation, and myopia onset in premyopic children.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Endocrinology & Metabolism
Alon Peled, Itamar Raz, Inbar Zucker, Estela Derazne, Jacob Megreli, Orit Pinhas-Hamiel, Adi Einan-Lifshitz, Yair Morad, Eran Pras, Miri Lutski, Tali Cukierman-Yaffe, Ofri Mosenzon, Dorit Tzur, Amir Tirosh, Hertzel C. Gerstein, Arnon Afek, Gilad Twig
Summary: A correlation between myopia in adolescence and the incidence of type 2 diabetes in young adulthood was found, especially among women and in a severity-dependent manner. This finding may support the role of insulin resistance in myopia pathogenesis.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Neurosciences
Safal Khanal, Thomas T. Norton, Timothy J. Gawne
Summary: The emmetropization feedback mechanism adjusts the axial growth of eyes based on visual cues to maintain clear focus on distant objects. Existing animal models of myopia do not accurately represent the stimuli that lead to human myopia. In our study, we developed an animal model using tree shrews that better mimics the slow progression of myopia seen in children by providing limited chromatic cues.
Article
Rheumatology
B. Schiappapietra, C. Bava, S. Rosina, A. Pistorio, F. Mongelli, S. Pederzoli, S. Verazza, S. Lanni, V Muratore, S. Davi, S. Dalpra, G. C. Varnier, M. Bertamino, C. Suffia, G. Bracciolini, G. Giancane, A. Consolaro, A. Ravelli
Summary: The number of affected joints and the CRP level in the first 6 months were identified as the strongest predictors of polyarticular extension in children with oligoarticular-onset JIA.
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
(2021)
Article
Nanoscience & Nanotechnology
Yao Chen, Jingjing Zhang, Hui Huang, Bo Su
Summary: This study investigated the effect of orthokeratology combined with visual motor training on juvenile myopia and found that the combined treatment was more effective in correcting myopia and delaying axial growth, with better results seen with earlier intervention.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2023)
Article
Psychology, Multidisciplinary
Shuhui Xu, Junwen Yu, Yu Hu
Summary: Exploring the formation mechanism of juvenile delinquency is important for preventing it. This study examined the relationships and interactions among self-consciousness, family factors, social relationships, belief in a just world, and legal consciousness of juvenile delinquents, and developed a predictive model to distinguish between delinquents and non-delinquents. The results showed that family factors significantly influence the formation of delinquents' self-consciousness and there are notable differences in family environment and self-consciousness between delinquent and non-delinquent adolescents. Due to complex interactions, self-consciousness and social relationships of adolescents can effectively predict and classify delinquent and non-delinquent groups. Therefore, improving self-consciousness and developing prosocial relationships are key to preventing juvenile delinquency.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Ophthalmology
Saiko Matsumura, Tadashi Matsumoto, Yuji Katayama, Masahiko Tomita, Hazuki Morikawa, Takashi Itokawa, Momoko Kawakami, Yuichi Hori
Summary: The purpose of this study was to investigate the prevalence of myopia and high myopia, as well as the risk factors for high myopia, in infants with retinopathy of prematurity (ROP) at 3 years of age. The results showed that the prevalence of myopia and high myopia was significantly higher in the treated group compared to the untreated group. The number of laser shots was identified as an independent risk factor for early onset high myopia.
JAPANESE JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Genetics & Heredity
Ralph van Mazijk, Annechien E. G. Haarman, Lies H. Hoefsloot, Jan R. Polling, Marianne van Tienhoven, Caroline C. W. Klaver, Virginie J. M. Verhoeven, Sjoukje E. Loudon, Alberta A. H. J. Thiadens, Anneke J. A. Kievit
Summary: This study describes the clinical spectrum and genetic background of high myopia caused by mutations in the ARR3 gene. It identified three families with early onset, therapy-resistant, high myopia with a female-limited inheritance pattern caused by a mutation in the ARR3 gene. Identification of this type of high myopia will improve prompt myopia treatment, monitoring, and genetic counseling.
Article
Medicine, General & Internal
Zhaoxin Jiang, Aohan Hou, Ting Zhang, Yanting Lai, Li Huang, Xiaoyan Ding
Summary: This study found that simple high myopia, familial exudative vitreoretinopathy (FEVR), and Stickler syndrome (STL) are the most common etiologies in children with early-onset high myopia (eoHM), and they exhibit different patterns of choroidal thickness. Asymmetric nasal choroidal thinning can serve as a biomarker for simple high myopia, asymmetric temporal choroidal thinning might serve as a biomarker for FEVR, and symmetric diffuse thinning is more common in STL.
FRONTIERS IN MEDICINE
(2023)
Article
Economics
Bill Byrom, Chris Watson, Helen Doll, Stephen Joel Coons, Sonya Eremenco, Rachel Ballinger, Marie Mc Carthy, Mabel Crescioni, Paul O'Donohoe, Cindy Howry
Article
Medical Informatics
Jenny J. Ly, Mabel Crescioni, Sonya Eremenco, Serge Bodart, Mario Donoso, Adam J. Butler, Susan M. Dallabrida
THERAPEUTIC INNOVATION & REGULATORY SCIENCE
(2019)
Article
Medical Informatics
Cindy Howry, Celeste A. Elash, Mabel Crescioni, Sonya Eremenco, Paul O'Donohoe, Tracey Rothrock
THERAPEUTIC INNOVATION & REGULATORY SCIENCE
(2019)
Article
Pediatrics
Adam J. Peiffer, James MacDonald, Drew Duerson, Gladys Mitchell, Andrew T. E. Hartwick, Catherine E. McDaniel
CLINICAL PEDIATRICS
(2020)
Article
Ophthalmology
G. Lynn Mitchell, Kathryn Richdale, Dawn Lam, Heidi Wagner, Beth T. Kinoshita, Aaron B. Zimmerman, Luigina Sorbara, Bernard Rosner
Summary: The development and validation of the Contact Lens Risk Survey (CLRS) showed excellent psychometric properties in identifying patients at risk for soft contact lens-related complications. The tool demonstrated good repeatability, consistency, and discriminative ability in distinguishing between individuals with and without red eye events related to contact lens wear.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Chandra V. Mickles, Beth T. Kinoshita, Dawn Lam, Heidi Wagner, Aaron B. Zimmerman, Luigina Sorbara, G. Lynn Mitchell, Bernard Rosner, Kathryn Richdale
Summary: The study tested the Contact Lens Assessment in Youth Contact Lens Risk Survey (CLRS) scoring algorithm in soft contact lens wearers and found significant differences between individuals presenting with soft contact lens-related adverse events and healthy controls, supporting the identification of high-risk patients and targeted interventions.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Katherine M. Bickle, G. Lynn Mitchell, Jeffrey J. Walline
Summary: This study compared the subjective and objective vision of children wearing different add power soft multifocal contact lenses, finding that +3.00 D and higher add powers may result in more vision-related issues, while the +2.00 D add power lenses were well tolerated by the subjects.
OPTOMETRY AND VISION SCIENCE
(2021)
Article
Ophthalmology
Eric Borsting, L. Eugene Arnold, G. Lynn Mitchell, Marjean Kulp, Mitchell Scheiman, Susan Cotter, Michael Gallaway, Ingryd Lorenzana, Christopher Chase, Lisa Jones-Jordan, Richard Hertle, Jeffrey Cooper, Erica Schulman, Kimberly Hamian, Danielle Iacono, Steven Larson, Valerie Leung, Sara Meeder, Elaine Ramos, Steven Ritter, Audra Steiner, Alexandria Stormann, Marilyn Vricella, Xiaoying Zhu, Susanna Tamkins, Naomi Aguilera, Elliot Brafman, Hilda Capo, Kara Cavuoto, Isaura Crespo, Monica Dowling, Kristie Draskovic, Miriam Farag, Vicky Fischer, Sara Grace, Ailen Gutierrez, Carolina Manchola Orozco, Maria Martinez, Oraig McKeown, Carla Osigian, Tuyet-Suong, Leslie Small, Natalie Townsend, Mark Boas, Christine Calvert, Tara Franz, Amanda Gerrouge, Donna Hayden, Erin Jenewein, Zachary Margolies, Shivakhaami Meiyeppen, Jenny Myung, Karen Pollack, Ruth Shoge, Andrew Tang, Noah Tannen, Lynn Trieu, Luis Trujillo, Michelle Buckland, Allison Ellis, Jennifer Fogt, Catherine McDaniel, Taylor McGann, Ann Morrison, Shane Mulvihill, Adam Peiffer, Maureen Plaumann, Gil Pierce, Julie Preston, Kathleen Reuter, Nancy Stevens, Jake Teeny, Andrew Toole, Douglas Widmer, Aaron Zimmerman, Carmen Barnhardt, Angela Chen, Raymond Chu, Kristine Huang, Susan Parker, Dashaini Retnasothie, Judith Wu, Penny Clark, Kelly Culp, Kathy Fraley, Drusilla Grant, Nancy Hanna, Stephanie Knox, William Lawhon, Sarah Mitcheff, Isabel Ricker, Tawna Roberts, Casandra Solis, Palak Wall, Samantha Zaczyk, Kristine Hopkins, Wendy Marsh-Tootle, Michelle Bowen, Terri Call, Kristy Domnanovich, Marcela Frazier, Nicole Guyette, Oakley Hayes, John Houser, Sarah Lee, Jenifer Montejo, Tamara Oechslin, Christian Spain, Candice Turner, Katherine Weise, Rachel Coulter, Deborah Amster, Annette Bade, Surbhi Barisal, Laura Falco, Gregory Fecho, Katherine Green, Gabriela Irizarry, Jasleen Jhajj, Nicole Patterson, Jacqueline Rodena, Yin Tea, Julie Tyler, Dana Weiss, Lauren Zakaib, Yesena Meza, Ryan Mann, Mariana Quezada, Scott Rein, Indre Rudaitis, Susan Stapleton, Beata Wajs, Maryann Redford, Carolyn Denton, Sharyl Wee, Katlynn Dahl-Leonard, Kenneth Powers, Amber Alaniz, Marie Diener-West, William Good, David Grisham, Christopher J. Kratochvil, Dennis Revicki, Jeanne Wanzek, Mustafa Alrahem, Julianne Dangelo, Jordan Hegedus, Ian Jones, Lisa A. Jones-Jordan, Alexander Junglas, Jihyun Lee, Jadin Nettles, Curtis Mitchell, Mawada Osman, Gloria Scott-Tibbs, Loraine Sinnott, Chloe Teasley, Victor Vang, Robin Varghese
Summary: The study compared the effects of vergence/accommodative therapy and placebo therapy on attention in children with convergence insufficiency. The results showed that both treatments did not significantly improve attention, but there were large within-group changes in attention in both treatment groups.
OPTOMETRY AND VISION SCIENCE
(2021)
Article
Ophthalmology
Rachel Anastasia Coulter, Annette Bade, Erin C. Jenewein, Yin C. Tea, G. Lynn Mitchell
Summary: Establishing a standard of care for autism spectrum disorder (ASD) children can help clinicians diagnose and manage vision problems more effectively. Results from this study show that ASD children tend to have more eye issues, such as receded near point of convergence and poor visual accuracy, regardless of their level of verbal communication.
OPTOMETRY AND VISION SCIENCE
(2021)
Article
Ophthalmology
Marjean T. Kulp, Loraine T. Sinnott, Susan A. Cotter, Eric Borsting, Andrew J. Toole, Angela M. Chen, Erin C. Jenewein, Ann M. Morrison, Maureen D. Plaumann, Lisa Jones-Jordan, G. Lynn Mitchell, Yin C. Tea, Mitchell M. Scheiman
Summary: Coexisting accommodative dysfunction in children with symptomatic CI is associated with worse NPC, but does not impact symptom severity in a clinically meaningful way. Concurrent accommodative dysfunction does not affect treatment response for CI.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2022)
Article
Multidisciplinary Sciences
Ryo Kubota, Nabin R. Joshi, Tara J. Fitzgerald, Inna Samandarova, Maksud Oliva, Arkady Selenow, Amitava Gupta, Steven Ali, G. Lynn Mitchell, Robert Chun, Kenneth J. Ciuffreda
Summary: The prevalence of myopia is increasing rapidly and is related to elongation of the eye. Previous research has shown that exposure to specific defocus stimuli can temporarily modify myopia, but how to convert these short-term effects into long-term changes is still unclear.
SCIENTIFIC REPORTS
(2022)
Article
Ophthalmology
Erin C. Jenewein, Susan Cotter, Tawna Roberts, Marjean Kulp, G. Lynn Mitchell, Lisa A. Jones-Jordan, Angela M. Chen, Kristine Hopkins, Kristine Huang, Deborah Amster, Gregory Fecho, Julie Tyler, Shivakhaami Meiyeppen, Mitchell Scheiman
Summary: This study aimed to evaluate the time course of improvements in clinical convergence measures for children with symptomatic convergence insufficiency treated with office-based vergence/accommodative therapy. The results showed that the greatest improvements occurred in the first 4 weeks of therapy, but there were ongoing improvements over the subsequent 12 weeks. Most participants achieved normal convergence after 12 weeks of therapy, but an additional 4 weeks of therapy may be beneficial for some participants.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Ophthalmology
Heidi Wagner, Aaron B. Zimmerman, Dawn Lam, Beth Kinoshita, Bernard Rosner, G. Lynn Mitchell, Kathryn Richdale
Summary: This study aims to compare the safety of daily disposable and reusable contact lenses, and finds that a portion of daily disposable lens wearers do not follow the proper usage method. Therefore, a stricter definition is needed for daily disposable lens wearers.
OPTOMETRY AND VISION SCIENCE
(2023)
Article
Ophthalmology
Emmanuel Owusu, Nahrain M. Shasteen, G. Lynn Mitchell, Melissa D. Bailey, Chiu-Yen Kao, Andrew J. Toole, Kathryn Richdale, Marjean T. Kulp
Summary: This study found that individuals with accommodative insufficiency have thinner ciliary muscles in the apical region and the ciliary muscle can thicken in response to increased workload. This may explain why symptoms improve with accommodative/vergence therapy.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Ophthalmology
Angela M. Chen, Tawna L. Roberts, Susan A. Cotter, Marjean T. Kulp, Loraine T. Sinnott, Eric J. Borsting, Yin C. Tea, Lisa A. Jones-Jordan, Richard Hertle, G. Lynn Mitchell, L. Eugene Arnold, Christopher Chase, Mitchell M. Scheiman
Summary: Office-based vergence/accommodative therapy is effective in improving accommodative function in children with symptomatic convergence insufficiency and coexisting accommodative dysfunction. The treatment group showed significantly greater improvements in accommodative amplitude and accommodative facility compared to the placebo group. The rate of improvement in amplitude and facility was faster in the early treatment period than in the later period.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)