Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region
出版年份 2012 全文链接
标题
Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region
作者
关键词
-
出版物
Nature Communications
Volume 3, Issue 1, Pages -
出版商
Springer Nature
发表日期
2012-09-04
DOI
10.1038/ncomms2046
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Biased Signaling Pathways in 2-Adrenergic Receptor Characterized by 19F-NMR
- (2012) J. J. Liu et al. SCIENCE
- Structural insights into agonist-induced activation of G-protein-coupled receptors
- (2011) Xavier Deupi et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Crystal structure of metarhodopsin II
- (2011) Hui-Woog Choe et al. NATURE
- Structure of a nanobody-stabilized active state of the β2 adrenoceptor
- (2011) Søren G. F. Rasmussen et al. NATURE
- Structure and function of an irreversible agonist-β2 adrenoceptor complex
- (2011) Daniel M. Rosenbaum et al. NATURE
- Crystal structure of the β2 adrenergic receptor–Gs protein complex
- (2011) Søren G. F. Rasmussen et al. NATURE
- Multiple ligand-specific conformations of the β2-adrenergic receptor
- (2011) Alem W Kahsai et al. Nature Chemical Biology
- Structure of an Agonist-Bound Human A2A Adenosine Receptor
- (2011) F. Xu et al. SCIENCE
- Ligand-Dependent Perturbation of the Conformational Ensemble for the GPCR β2 Adrenergic Receptor Revealed by HDX
- (2011) Graham M. West et al. STRUCTURE
- β-arrestin-mediated receptor trafficking and signal transduction
- (2011) Sudha K. Shenoy et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The selectivity of β-adrenoceptor agonists at human β1-, β2- and β3-adrenoceptors
- (2010) Jillian G Baker BRITISH JOURNAL OF PHARMACOLOGY
- Conformational dependence of 13C shielding and coupling constants for methionine methyl groups
- (2010) Glenn L. Butterfoss et al. JOURNAL OF BIOMOLECULAR NMR
- Conserved Binding Mode of Human β2Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography
- (2010) Daniel Wacker et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
- (2010) Michael P. Bokoch et al. NATURE
- Clinical implications of the intrinsic efficacy of beta-adrenoceptor drugs in asthma: full, partial and inverse agonism
- (2009) Nicola A Hanania et al. CURRENT OPINION IN PULMONARY MEDICINE
- The structure and function of G-protein-coupled receptors
- (2009) Daniel M. Rosenbaum et al. NATURE
- The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
- (2009) X. J. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dependence of Amino Acid Side Chain13C Shifts on Dihedral Angle: Application to Conformational Analysis
- (2008) Robert E. London et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structural diversity of G protein-coupled receptors and significance for drug discovery
- (2008) Malin C. Lagerström et al. NATURE REVIEWS DRUG DISCOVERY
- A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor
- (2008) Michael A. Hanson et al. STRUCTURE
- Stabilization of the Human β2-Adrenergic Receptor TM4–TM3–TM5 Helix Interface by Mutagenesis of Glu1223.41, A Critical Residue in GPCR Structure
- (2007) Christopher B. Roth et al. JOURNAL OF MOLECULAR BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now