miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia

Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells

(2011) Lan-Lan Smith et al.   Cell Stem Cell

MicroRNA programs in normal and aberrant stem and progenitor cells

(2011) C. P. Arnold et al.   GENOME RESEARCH

Leukemogenic transformation by HOXA cluster genes

(2010) C. Bach et al.   BLOOD

Meis1 maintains stemness signature in MLL-AF9 leukemia

(2010) A. R. Kumar et al.   BLOOD

The prognostic and functional role of microRNAs in acute myeloid leukemia

(2010) G. Marcucci et al.   BLOOD

MicroRNAs expression signatures are associated with lineage and survival in acute leukemias

(2010) Yungui Wang et al.   BLOOD CELLS MOLECULES AND DISEASES

Ratio of miR-196s to HOXC8 Messenger RNA Correlates with Breast Cancer Cell Migration and Metastasis

(2010) Y. Li et al.   CANCER RESEARCH

AP-1 — The Jun proteins: Oncogenes or tumor suppressors in disguise?

(2010) Eitan Shaulian   CELLULAR SIGNALLING

Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia

(2010) D. Schotte et al.   HAEMATOLOGICA

Functional genomics of tumor suppressor miR-196b in T-cell acute lymphoblastic leukemia

(2010) Suman Bhatia et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Potential tumor suppressive function of miR-196b in B-cell lineage acute lymphoblastic leukemia

(2010) Suman Bhatia et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Might as well face it: MLL's addicted to HOX

(2009) J. J. Roth et al.   BLOOD

Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization

(2009) R. Popovic et al.   BLOOD

Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome

(2009) B. J. Wouters et al.   BLOOD

MicroRNA Control in the Immune System: Basic Principles

(2009) Changchun Xiao et al.   CELL

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

The molecular biology of mixed lineage leukemia

(2009) R. K. Slany   HAEMATOLOGICA

Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss

(2009) Ángeles Mencía et al.   NATURE GENETICS

HOXA9 is required for survival in human MLL-rearranged acute leukemias

(2008) J. Faber et al.   BLOOD

A role for MEIS1 in MLL-fusion gene leukemia

(2008) A. R. Kumar et al.   BLOOD

H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias

(2008) Andrei V. Krivtsov et al.   CANCER CELL

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

MicroRNAs in the Hox network: an apparent link to posterior prevalence

(2008) Soraya Yekta et al.   NATURE REVIEWS GENETICS

MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression

(2008) F. E. Erfurth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations

(2008) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA