Article
Cell Biology
Qunshan Lu, Peilai Liu, Zhuang Miao, Desu Luo, Songlin Li, Mei Lu
Summary: Our study demonstrates that SIRT1 can inhibit EGFR ubiquitination by down-regulating PTEN, thereby preventing extracellular matrix degradation and activating chondrocyte autophagy. Knockdown of SIRT1 accelerates the progression of osteoarthritis in the pathological process.
CELL DEATH DISCOVERY
(2022)
Article
Biochemistry & Molecular Biology
Fang Li, Xinguo You, Qinfeng Li, Di Qin, Mengyang Wang, Shipeng Yuan, Xiguang Chen, Shichao Bi
Summary: This study focused on verifying the structural stability, homogeneous degradation, and deacetylation of chitin in alkali-soluble systems. The results showed significant changes in chitin with an increase in storage time and temperature, but the processed chitins were non-toxic for biomedicine applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Zhuoxian Cao, Zhicheng Gu, Shuxian Lin, Di Chen, Jie Wang, Yonglong Zhao, Yan Li, Ting Liu, Yongjun Li, Yi Wang, Hening Lin, Bin He
Summary: HDAC6 is a potential therapeutic target for treating various diseases, and a degrader targeting HDAC6 can efficiently reduce its levels in cells and attenuate NLRP3 inflammasome activation.
ACS CHEMICAL BIOLOGY
(2021)
Article
Polymer Science
Jobu Tateiwa, Satoshi Kimura, Ken-ichi Kasuya, Tadahisa Iwata
Summary: This study investigated the effect of coating a non-biodegradable polymer on the degradation of a biodegradable polymer film. The results showed that the coated films had less degradation in the presence of enzymes, but the surface-deacetylated coated films could be degraded. Additionally, it was found that the coated films underwent deacetylation in seawater and exposed the underlying material, thereby promoting degradation.
POLYMER DEGRADATION AND STABILITY
(2022)
Article
Polymer Science
Nattanan Chulikavit, Tien Huynh, Cheng Wang, Anthony Chun Yin Yuen, Akbar Khatibi, Adrian Mouritz, Everson Kandare
Summary: This paper investigates the effect of alkaline deacetylation on the mycelium fungi and reveals the relationship between the degree of deacetylation and thermal properties. It also explores the impact of an oxidizing agent, KMnO4, on the thermal stability of treated mycelium. The research findings contribute to the development and design of bio-derived thermal protection materials.
POLYMER DEGRADATION AND STABILITY
(2023)
Article
Materials Science, Multidisciplinary
Nisha Yadav, Minna Hakkarainen
Summary: Cellulose acetate undergoes weight loss in aqueous environments due to deacetylation. The initial months of a 12-month study showed significant weight loss, with temperature having minimal effect. The degree of substitution (DS) is a crucial factor in the biodegradation of cellulose acetate, with lower DS resulting in higher degradation rates.
MACROMOLECULAR MATERIALS AND ENGINEERING
(2022)
Article
Engineering, Environmental
Liuliu Li, Wenyue Yan, Baogang Zhang, Han Zhang, Rongyue Geng, Sijia Sun, Xiaohong Guan
Summary: This study demonstrates for the first time that pyrrhotite can successfully bioreduce toxic selenate under anaerobic conditions. Complete removal of selenate was achieved in a continuous column experiment using indigenous microbial consortium and pyrrhotite. The study also revealed the importance of hydrochemistry and hydrodynamics in the performance of selenate removal.
Review
Biochemistry & Molecular Biology
Chayanaphat Chokradjaroen, Jiangqi Niu, Gasidit Panomsuwan, Nagahiro Saito
Summary: Researchers are exploring renewable materials like nature-derived polysaccharides to add value by changing chemical structures for specific properties. The solution plasma process offers a novel method for modifying polysaccharides like chitin and chitosan, aiming to reduce hazardous chemicals, simplify production steps, and acquire high-purified products. Intensive explanation of influencing parameters in the plasma process provides a guideline for modifying polysaccharides to address economic aspects and environmental concerns.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Engineering, Environmental
Liuliu Li, Baogang Zhang, Lei Li, Alistair G. L. Borthwick
Summary: The study demonstrated the feasibility of using elemental sulfur as an electron donor to support selenium bioreduction. Involvement of Thiobacillus, Desulfurivibrio, and Sulfuricurvum bacteria indicated coupling of Se(VI) reduction with S(0) oxidation, showing microbial synergy in the process.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Polymer Science
Wen Lin, Yujin Zhao, Tingting Su, Zhanyong Wang
Summary: The degradation behavior of PBAT films by different concentrations of Fusarium solani cutinase (FsC) was investigated. It was found that FsC could degrade both the amorphous region and the crystalline region of PBAT films, and its degradation activity was concentration-dependent. High concentration of FsC resulted in significant degradation of PBAT films, while low concentration had less apparent effect. FsC concentration and degradation time did not significantly affect the molecular weight of degraded PBAT.
POLYMER DEGRADATION AND STABILITY
(2023)
Article
Food Science & Technology
Davide Ferrigo, Valentina Scarpino, Francesca Vanara, Roberto Causin, Alessandro Raiola, Massimo Blandino
Summary: This study examined the effect of H2O2-induced oxidative stress on fungal growth and mycotoxin production in Fusarium proliferatum and Fusarium subglutinans. The results showed that H2O2 could affect fungal growth and mycotoxin stability in these fungi.
Review
Agriculture, Multidisciplinary
Sebahat Oztekin, Dilara Nur Dikmetas, Dilara Devecioglu, Emine Gizem Acar, Funda Karbancioglu-Guler
Summary: Fungi-induced postharvest diseases are a major cause of food loss and waste. Antagonistic yeasts provide a biological method to control decay caused by fungi and detoxify mycotoxins sustainably. This review summarizes studies on preventing phytopathogenic and mycotoxigenic fungi in fruits and their biocontrolling and biodetoxification mechanisms.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Sungkwon Park, Jinsu Koo, Bosung Kim, Karthika Pushparaj, Arunkumar Malaisamy, Wen-Chao Liu, Balamuralikrishnan Balasubramanian
Summary: The present study evaluated the properties and ochratoxin A (OTA) degradation capacity of a dietary probiotic Pediococcus pentosaceus BalaMMB-P3. The strain exhibited good acid tolerance, nonpathogenicity, antibiotic susceptibility, enzymatic activity, and antifungal activity. The compound showed carcinogenic and cytotoxicity effects, and the strain showed a potent ability to reduce OTA, suggesting its potential utilization in food nutrition.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Food Science & Technology
Ksenija Nesic, Kristina Habschied, Kresimir Mastanjevic
Summary: Research on biological detoxification of mycotoxins has made significant progress in recent years. Analysis of literature data shows that microorganisms such as yeast, bacteria, fungi, and enzymes can degrade or adsorb mycotoxins, enhancing the safety and quality of crops, animal feed, and food products.
Article
Cell Biology
Yanan Li, Shujing Li, Xiaoxia Shi, Zhiqiang Xin, Yuxi Yang, Binggong Zhao, Yvlin Li, Linlin Lv, Ping Ren, Huijian Wu
Summary: KLF12 gene plays a role in promoting proliferation and inhibiting apoptosis in breast cancer. It affects the stability and acetylation of p53 protein and transcription of p21 gene, suggesting its importance as a prognostic marker and therapeutic target in breast cancer.
CELL DEATH & DISEASE
(2023)