Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways

Acetylation of FoxO1 Activates Bim Expression to Induce Apoptosis in Response to Histone Deacetylase Inhibitor Depsipeptide Treatment

(2015) Yang Yang et al.   NEOPLASIA

HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy

(2014) A. W. Beharry et al.   JOURNAL OF CELL SCIENCE

Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A

(2014) Guillermo Mariño et al.   MOLECULAR CELL

The emerging role of acetylation in the regulation of autophagy

(2013) Ágnes Bánréti et al.   Autophagy

The ULK1 complex

(2013) Pui-Mun Wong et al.   Autophagy

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

(2013) Ying Zhao et al.   CELL RESEARCH

FOXOs: signalling integrators for homeostasis maintenance

(2013) Astrid Eijkelenboom et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Amino acid signalling upstream of mTOR

(2013) Jenna L. Jewell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway

(2012) Jingyi Zhou et al.   Autophagy

Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage

(2012) Jing Han et al.   Autophagy

Induction of Autophagy by Palmitic Acid via Protein Kinase C-mediated Signaling Pathway Independent of mTOR (Mammalian Target of Rapamycin)

(2012) Shi Hao Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combination of Pan-Histone Deacetylase Inhibitor and Autophagy Inhibitor Exerts Superior Efficacy against Triple-Negative Human Breast Cancer Cells

(2012) R. Rao et al.   MOLECULAR CANCER THERAPEUTICS

Benzyl Isothiocyanate Causes FoxO1-Mediated Autophagic Death in Human Breast Cancer Cells

(2012) Dong Xiao et al.   PLoS One

Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death

(2012) N. Gammoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function and Molecular Mechanism of Acetylation in Autophagy Regulation

(2012) C. Yi et al.   SCIENCE

GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy

(2012) S.-Y. Lin et al.   SCIENCE

Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome

(2011) Eugenia Morselli et al.   JOURNAL OF CELL BIOLOGY

Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

(2010) Yuan-Ling Liu et al.   Autophagy

Life or death? Autophagy in anticancer therapies with statins and histone deacetylase inhibitors

(2010) Pei-Ming Yang et al.   Autophagy

Autophagic Survival in Resistance to Histone Deacetylase Inhibitors: Novel Strategies to Treat Malignant Peripheral Nerve Sheath Tumors

(2010) G. Lopez et al.   CANCER RESEARCH

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and Rictor

(2010) Chia-Chen Chen et al.   DEVELOPMENTAL CELL

Discovery of Novel Forkhead Box O1 Inhibitors for Treating Type 2 Diabetes: Improvement of Fasting Glycemia in Diabetic db/db Mice

(2010) T. Nagashima et al.   MOLECULAR PHARMACOLOGY

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy

(2009) L. Ellis et al.   BLOOD

Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation

(2009) Jennifer S. Carew et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Dynamics and diversity in autophagy mechanisms: lessons from yeast

(2009) Hitoshi Nakatogawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway

(2008) A Hrzenjak et al.   JOURNAL OF PATHOLOGY

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unravelling the tumor-suppressive functions of FOXO proteins

(2008) Tobias B. Dansen et al.   TRENDS IN CELL BIOLOGY