Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease
出版年份 2012 全文链接
标题
Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease
作者
关键词
-
出版物
Epigenomics
Volume 4, Issue 2, Pages 163-177
出版商
Future Medicine Ltd
发表日期
2012-03-27
DOI
10.2217/epi.12.3
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Spectrum of MLL2 (ALR) mutations in 110 cases of Kabuki syndrome
- (2011) Mark C. Hannibal et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Kleefstra syndrome in three adult patients: Further delineation of the behavioral and neurological phenotype shows aspects of a neurodegenerative course
- (2011) Willem M.A. Verhoeven et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A
- (2011) A. M. Jankowska et al. BLOOD
- Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network
- (2011) Yen-Sin Ang et al. CELL
- Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells
- (2011) Jungmook Lyu et al. CELL RESEARCH
- Aberrations of EZH2 in Cancer
- (2011) A. Chase et al. CLINICAL CANCER RESEARCH
- Polycomb-mediated repression during terminal differentiation: what don't you want to be when you grow up?
- (2011) M. L. Conerly et al. GENES & DEVELOPMENT
- A mutation screen in patients with Kabuki syndrome
- (2011) Yun Li et al. HUMAN GENETICS
- Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model
- (2011) Yi Chun Chen et al. HUMAN MOLECULAR GENETICS
- Deregulated transcription factors in leukemia
- (2011) Yutaka Shima et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- The heterodimerization domains of MLL—FYRN and FYRC—are potential target structures in t(4;11) leukemia
- (2011) B Pless et al. LEUKEMIA
- Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance
- (2011) V Grossmann et al. LEUKEMIA
- CREBBP mutations in relapsed acute lymphoblastic leukaemia
- (2011) Charles G. Mullighan et al. NATURE
- Inactivating mutations of acetyltransferase genes in B-cell lymphoma
- (2011) Laura Pasqualucci et al. NATURE
- Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
- (2011) Ryan D. Morin et al. NATURE
- Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
- (2011) Ignacio Varela et al. NATURE
- Initial genome sequencing and analysis of multiple myeloma
- (2011) Michael A. Chapman et al. NATURE
- Analysis of the coding genome of diffuse large B-cell lymphoma
- (2011) Laura Pasqualucci et al. NATURE GENETICS
- Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
- (2011) Yaoting Gui et al. NATURE GENETICS
- Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data
- (2011) Gregory M. Cooper et al. NATURE REVIEWS GENETICS
- Exome sequencing as a tool for Mendelian disease gene discovery
- (2011) Michael J. Bamshad et al. NATURE REVIEWS GENETICS
- Constitutional tandem duplication of 9q34 that truncates EHMT1 in a child with ganglioglioma
- (2011) Hannah C. Cheung et al. PEDIATRIC BLOOD & CANCER
- Chromatin "Prepattern" and Histone Modifiers in a Fate Choice for Liver and Pancreas
- (2011) C.-R. Xu et al. SCIENCE
- Chromatin Regulatory Mechanisms in Pluripotency
- (2010) Julie A. Lessard et al. Annual Review of Cell and Developmental Biology
- EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis
- (2010) I. Velichutina et al. BLOOD
- Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
- (2010) D. B. Yap et al. BLOOD
- The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells
- (2010) E. Martinez-Garcia et al. BLOOD
- Mechanisms of leukemogenesis by MLL fusion proteins
- (2010) Rolf Marschalek BRITISH JOURNAL OF HAEMATOLOGY
- MLL fusions: Pathways to leukemia
- (2010) Han Liu et al. CANCER BIOLOGY & THERAPY
- Exome sequencing: expanding the genetic testing toolbox
- (2010) CE Kobelka CLINICAL GENETICS
- Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment
- (2010) O. Alder et al. DEVELOPMENT
- Hox genes and regional patterning of the vertebrate body plan
- (2010) Moises Mallo et al. DEVELOPMENTAL BIOLOGY
- Epigenetic regulation of vertebrateHoxgenes: A dynamic equilibrium
- (2010) Natalia Soshnikova et al. Epigenetics
- MLL2 mutation spectrum in 45 patients with Kabuki syndrome
- (2010) Aimée D. C. Paulussen et al. HUMAN MUTATION
- OCT3/4 regulates transcription of histone deacetylase 4 (Hdac4) in mouse embryonic stem cells
- (2010) Russell C. Addis et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies
- (2010) H Makishima et al. LEUKEMIA
- Epigenetic Modification Affecting Expression of Cell Polarity and Cell Fate Genes to Regulate Lineage Specification in the Early Mouse Embryo
- (2010) David-Emlyn Parfitt et al. MOLECULAR BIOLOGY OF THE CELL
- A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation
- (2010) Daniela Kleine-Kohlbrecher et al. MOLECULAR CELL
- Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
- (2010) Gillian L. Dalgliesh et al. NATURE
- JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells
- (2010) Diego Pasini et al. NATURE
- Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
- (2010) Gorica Nikoloski et al. NATURE GENETICS
- Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
- (2010) Ryan D Morin et al. NATURE GENETICS
- Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
- (2010) Thomas Ernst et al. NATURE GENETICS
- Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome
- (2010) Sarah B Ng et al. NATURE GENETICS
- Disruption of the epigenetic code: An emerging mechanism in mental retardation
- (2010) Hans van Bokhoven et al. NEUROBIOLOGY OF DISEASE
- Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes
- (2010) Diego Pasini et al. NUCLEIC ACIDS RESEARCH
- TNF Inhibits Notch-1 in Skeletal Muscle Cells by Ezh2 and DNA Methylation Mediated Repression: Implications in Duchenne Muscular Dystrophy
- (2010) Swarnali Acharyya et al. PLoS One
- Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation
- (2010) O. M. Dovey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Genetic Landscape of the Childhood Cancer Medulloblastoma
- (2010) D. W. Parsons et al. SCIENCE
- Ezh2 Orchestrates Gene Expression for the Stepwise Differentiation of Tissue-Specific Stem Cells
- (2009) Elena Ezhkova et al. CELL
- Jarid2/Jumonji Coordinates Control of PRC2 Enzymatic Activity and Target Gene Occupancy in Pluripotent Cells
- (2009) Jamy C. Peng et al. CELL
- Jumonji Modulates Polycomb Activity and Self-Renewal versus Differentiation of Stem Cells
- (2009) Xiaohua Shen et al. CELL
- Identification and characterization of two novel JARID1C mutations: suggestion of an emerging genotype–phenotype correlation
- (2009) Sinitdhorn Rujirabanjerd et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Clinical and molecular overview of inherited disorders resulting from epigenomic dysregulation
- (2009) Albertina De Sario European Journal of Medical Genetics
- Bmi-1 regulates the Ink4a/Arf locus to control pancreatic -cell proliferation
- (2009) S. Dhawan et al. GENES & DEVELOPMENT
- Polycomb protein Ezh2 regulates pancreatic -cell Ink4a/Arf expression and regeneration in diabetes mellitus
- (2009) H. Chen et al. GENES & DEVELOPMENT
- Histone deacetylase HDAC1/HDAC2-controlled embryonic development and cell differentiation
- (2009) Reinhard Brunmeir et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- Histone Deacetylases 1 and 2 Form a Developmental Switch That Controls Excitatory Synapse Maturation and Function
- (2009) M. W. Akhtar et al. JOURNAL OF NEUROSCIENCE
- Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
- (2009) Gijs van Haaften et al. NATURE GENETICS
- Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
- (2009) Paul A Northcott et al. NATURE GENETICS
- Polycomb Limits the Neurogenic Competence of Neural Precursor Cells to Promote Astrogenic Fate Transition
- (2009) Yusuke Hirabayashi et al. NEURON
- Mbd3, a Component of NuRD/Mi-2 Complex, Helps Maintain Pluripotency of Mouse Embryonic Stem Cells by Repressing Trophectoderm Differentiation
- (2009) Dongmei Zhu et al. PLoS One
- CARM1 Is Required in Embryonic Stem Cells to Maintain Pluripotency and Resist Differentiation
- (2009) Qiang Wu et al. STEM CELLS
- Maintenance of Undifferentiated State and Self-Renewal of Embryonic Neural Stem Cells by Polycomb Protein Ring1B
- (2009) Mónica Román-Trufero et al. STEM CELLS
- Loss of Mll5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation
- (2008) M. Heuser et al. BLOOD
- Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity
- (2008) M. Endoh et al. DEVELOPMENT
- Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos
- (2008) Pengpeng Ma et al. DEVELOPMENTAL BIOLOGY
- Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia
- (2008) M. G. Guenther et al. GENES & DEVELOPMENT
- Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells
- (2008) Jiancong Liang et al. NATURE CELL BIOLOGY
- De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
- (2008) Silvina Epsztejn-Litman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Differentiation of Neural Stem Cells into Oligodendrocytes: Involvement of the Polycomb Group Protein Ezh2
- (2008) Falak Sher et al. STEM CELLS
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