EZH2 promotes DNA replication by stabilizing interaction of POLδ and PCNA via methylation-mediated PCNA trimerization

Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation

(2017) Svetlana Petruk et al.   MOLECULAR CELL

EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation

(2017) Beatrice Rondinelli et al.   NATURE CELL BIOLOGY

The Oncogenic Polycomb Histone Methyltransferase EZH2Methylates Lysine 120 on Histone H2B and Competes Ubiquitination

(2015) Masaharu Kogure et al.   NEOPLASIA

Non-histone protein methylation as a regulator of cellular signalling and function

(2014) Kyle K. Biggar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Licensing of DNA replication, cancer, pluripotency and differentiation: An interlinked world?

(2014) S. Champeris Tsaniras et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication

(2014) Andrea Piunti et al.   Nature Communications

Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells

(2013) Eunhee Kim et al.   CANCER CELL

Polycomb repressive complex 2 contributes to DNA double-strand break repair

(2013) Stuart Campbell et al.   CELL CYCLE

Polycomb complex recruitment in pluripotent stem cells

(2013) Maria J. Barrero et al.   NATURE CELL BIOLOGY

Regulation of PCNA–protein interactions for genome stability

(2013) Niels Mailand et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone Lysine Methyltransferase SETD8 Promotes Carcinogenesis by Deregulating PCNA Expression

(2012) M. Takawa et al.   CANCER RESEARCH

TrxG and PcG Proteins but Not Methylated Histones Remain Associated with DNA through Replication

(2012) Svetlana Petruk et al.   CELL

PRC2 directly methylates GATA4 and represses its transcriptional activity

(2012) A. He et al.   GENES & DEVELOPMENT

EZH2 Generates a Methyl Degron that Is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex

(2012) Ji Min Lee et al.   MOLECULAR CELL

Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact

(2012) Joshua C. Black et al.   MOLECULAR CELL

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Histone methylation: a dynamic mark in health, disease and inheritance

(2012) Eric L. Greer et al.   NATURE REVIEWS GENETICS

Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage

(2011) Z Wu et al.   CELL DEATH AND DIFFERENTIATION

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

(2010) D. M. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a novel, widespread, and functionally important PCNA-binding motif

(2009) Karin M. Gilljam et al.   JOURNAL OF CELL BIOLOGY

ATXR5 and ATXR6 are H3K27 monomethyltransferases required for chromatin structure and gene silencing

(2009) Yannick Jacob et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A model for transmission of the H3K27me3 epigenetic mark

(2008) Klaus H. Hansen et al.   NATURE CELL BIOLOGY

Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1

(2008) M E Gonzalez et al.   ONCOGENE