The histone deacetylase inhibitor sodium valproate causes limited transcriptional change in mouse embryonic stem cells but selectively overrides Polycomb-mediated Hoxb silencing

Genes Are Often Sheltered from the Global Histone Hyperacetylation Induced by HDAC Inhibitors

(2012) John Halsall et al.   PLoS One

Valproic Acid Downregulates RBP4 and Elicits Hypervitaminosis A-Teratogenesis—A Kinetic Analysis on Retinol/Retinoic Acid Homeostatic System

(2012) Chao-Ming Chuang et al.   PLoS One

The adjustable nucleosome: an epigenetic signaling module

(2012) Bryan M. Turner   TRENDS IN GENETICS

The promotion of stemness and pluripotency following feeder-free culture of embryonic stem cells on collagen-grafted 3-dimensional nanofibrous scaffold

(2011) Seyed Mahmoud Hashemi et al.   BIOMATERIALS

Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains

(2011) Hao Jiang et al.   CELL

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Pluripotency-related, Valproic Acid (VPA)-induced Genome-wide Histone H3 Lysine 9 (H3K9) Acetylation Patterns in Embryonic Stem Cells

(2011) Hadas Hezroni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Valproic Acid Increases Formation of Reactive Oxygen Species and Induces Apoptosis in Postimplantation Embryos: A Role for Oxidative Stress in Valproic Acid-Induced Neural Tube Defects

(2011) E. W. Y. Tung et al.   MOLECULAR PHARMACOLOGY

Relative overexpression of X-linked genes in mouse embryonic stem cells is consistent with Ohno's hypothesis

(2011) Hong Lin et al.   NATURE GENETICS

Histone modification: cause or cog?

(2011) Steven Henikoff et al.   TRENDS IN GENETICS

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

(2010) Qihuang Jin et al.   EMBO JOURNAL

Polycomb complexes act redundantly to repress genomic repeats and genes

(2010) M. Leeb et al.   GENES & DEVELOPMENT

Epigenomic Reorganization of the Clustered Hox Genes in Embryonic Stem Cells Induced by Retinoic Acid

(2010) Vasundhra Kashyap et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

(2010) Diego Pasini et al.   NUCLEIC ACIDS RESEARCH

Histone deacetylases and epigenetic therapies of hematological malignancies

(2010) Ciro Mercurio et al.   PHARMACOLOGICAL RESEARCH

Histone deacetylase inhibitors as anti-neoplastic agents

(2009) Nicolas Batty et al.   CANCER LETTERS

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

Histone deacetylase inhibitors: Potential in cancer therapy

(2009) P.A. Marks et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Transcription-Independent Heritability of Induced Histone Modifications in the Mouse Preimplantation Embryo

(2009) Matthew D. VerMilyea et al.   PLoS One

Histone modifying enzymes: Structures, mechanisms, and specificities

(2008) Ronen Marmorstein et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

How does noncoding transcription regulate Hox genes?

(2008) Adelheid Lempradl et al.   BIOESSAYS

Valproic acid as epigenetic cancer drug: Preclinical, clinical and transcriptional effects on solid tumors

(2008) Alfonso Duenas-Gonzalez et al.   CANCER TREATMENT REVIEWS

Oral valproic acid for epilepsy - long-term experience in therapy and side effects

(2008) Thorsten Gerstner et al.   EXPERT OPINION ON PHARMACOTHERAPY

Moving AHEAD with an international human epigenome project

(2008) et al.   NATURE

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS

Teratogenicity of Antiepileptic Medications

(2008) Benzi Kluger et al.   SEMINARS IN NEUROLOGY