Supramolecular Ferric Porphyrins as Cyanide Receptors in Aqueous Solution

All fundamental data about binding of the cyanide to a supramolecular complex composed of a per-O-methylated beta-cyclodextrin dimer having an imidazole linker (Im3CD) and an anionic ferric porphyrin ((FeTPPS)-T-(III)) indicate that the (FeTPPS)-T-(III)/Im3CD complex is much better as an cyanide receptor in vivo than hydroxocobalamin, whose cyanide binding ability is lowered by its strong binding to serum proteins in the blood.