Article
Medicine, General & Internal
Li Shi, Xiaoju Li, Wei Liao, Wenxin Wu, Ming Xu
Summary: This study evaluated and monitored the changes in thermal ablation of rabbit liver using real-time elastography (RTE) and shear wave elastography (SWE), compared to contrast-enhanced ultrasound (CEUS) and physical specimens. The results showed that RTE and SWE could accurately confirm the shape of the ablation zones shortly after the ablation, and there was a high consistency between the two methods. The area measurements by CEUS were significantly larger than those of the other three methods. Therefore, RTE and SWE are effective in accurately determining the range of ablation zones after the ablation.
Article
Radiology, Nuclear Medicine & Medical Imaging
Camille Nallet, Lionel Pazart, Claire Cochet, Chrystelle Vidal, Jean-Patrick Metz, Emmanuelle Jacquet, Guillaume Gorincour, Nicolas Mottet
Summary: This study quantified and modeled the elasticities of normal fetal lungs and livers using 2D-SWE technology between 24 and 39 weeks of gestation. The results showed that the elasticities of the fetal lungs and livers evolved differently throughout gestation, possibly reflecting the tissue maturation of the organs. The reliability and repeatability of elasticity values were affected by the distance between the probe and the target organ.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jie Zhou, Feng Yan, Jinshun Xu, Qiang Lu, Xianglan Zhu, Binyang Gao, Huan Zhang, Rui Yang, Yan Luo
Summary: The study evaluated the accuracy of 2D-SWE in diagnosing steatohepatitis and fibrosis in NAFLD patients, compared with four noninvasive fibrotic biomarker scores. 2D-SWE showed excellent diagnostic performance for both steatohepatitis and fibrosis stages, with high AUROC values. Importantly, the diagnostic efficiency of 2D-SWE was not influenced by steatosis levels.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Review
Medicine, General & Internal
Ritesh Chimoriya, Milan K. Piya, David Simmons, Golo Ahlenstiel, Vincent Ho
Summary: Obesity is closely related to significant comorbidities, including non-alcoholic fatty liver disease, highlighting the importance of monitoring liver fibrosis. Developing non-invasive diagnostic methods for the rising prevalence of obesity and NAFLD is crucial. Two-dimensional shear wave elastography (2D-SWE) shows promise as a novel and non-invasive method for assessing liver fibrosis in patients with obesity and NAFLD.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Anna S. Morr, Helge Herthum, Felix Schrank, Steffen Goerner, Matthias S. Anders, Markus Lerchbaumer, Hans-Peter Mueller, Thomas Fischer, Klaus-Vitold Jenderka, Hendrik H. G. Hansen, Paul A. Janmey, Juergen Braun, Ingolf Sack, Heiko Tzschatzsch
Summary: This study introduces a phantom that mimics the stiffness dispersion of the human liver, allowing for improved standardization of liver elastography across ultrasound and MRI devices. The phantom shows good reproducibility and low variability, making it useful for establishing standard liver stiffness measurements.
INVESTIGATIVE RADIOLOGY
(2022)
Review
Physics, Multidisciplinary
Javier Brum, Nicolas Benech, Thomas Gallot, Carlos Negreira
Summary: Shear wave elastography (SWE) utilizes coherent shear waves to image tissue shear elasticity, but faces limitations in coherent shear wave tracking. An alternative approach has been developed to extract tissue shear elasticity from a complex elastic wavefield, overcoming these limitations and paving the way for innovative developments in multi-modality elastography. The compatibility of this approach with low imaging rates modalities has led to new challenges and applications in the field.
FRONTIERS IN PHYSICS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Arthur Pearson, Paul-Armand Dujardin, Louis d'Alteroche, Frederic Patat, Beatrice Scotto, Fanny Dujardin, Cecile Bastard, Veronique Miette, Laurent Sandrin, Jean-Pierre Remenieras
Summary: This study chose to use FibroScan for the diagnosis of nonalcoholic fatty liver disease (NAFLD) and developed an algorithm applying the Voigt rheological model to evaluate the viscoelastic properties of the liver. The results showed that our novel method successfully separated the two viscoelastic properties of the liver, and the parameter eta was found to be a sensitive indicator for steatosis.
Article
Acoustics
Cheng Fang, Vasileios Rafailidis, Eleni Konstantatou, Gibran T. Yusuf, Ian Barrow, Eirini Pagkalidou, Odyssefs Romanos, Kosh Agarwal, Alberto Quaglia, Paul S. Sidhu
Summary: This study evaluates the utility of 2-D shear wave elastography (SWE) in assessing liver fibrosis in patients with chronic liver disease. It compared the performance of 2-D SWE with point shear wave elastography (pSWE), using liver histological staging as the reference standard. The results showed that 2-D SWE provides feasible and accurate assessment of liver fibrosis, comparable to that of pSWE.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2022)
Article
Acoustics
Seung Hee Choi, Eun Young Ko, Boo-Kyung Han, Eun Sook Ko, Ji Soo Choi, Ko Woon Park
Summary: This study found that the presence of calcifications significantly increased the elasticity of breast lesions, and shear-wave elastography should be carefully interpreted in benign lesions with calcifications and in situ carcinomas without calcifications.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jun Cui, Qiang Du, Wei Fu
Summary: Shear wave elastography (SWE) is an effective tool for diagnosing and differentiating spermatogenetic dysfunction in males of reproductive age. The study found that in patients with spermatogenic defects, testicular stiffness was higher, and there was a positive correlation between testicular volume and sperm concentration.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Rie Nakayama, Yoichi Takaya, Kazufumi Nakamura, Norihisa Toh, Hiroshi Ito
Summary: This study evaluated the efficacy of SWE in assessing liver function in patients with HF, finding changes in elasticity and dispersion slope of shear wave across different stages of HF. SWE may be valuable in managing therapeutic strategies for patients with HF.
Article
Acoustics
Christophe Cassinotto, Sophie Anselme, Tony Jacq, Marie Irles-Depe, Ali Belgour, Margaux Hermida, Boris Guiu, Victor De Ledinghen
Summary: This study aimed to compare the value distribution of liver stiffness measurements obtained by different devices. Significant discrepancies were found between different devices in measuring liver stiffness in patients with chronic liver disease.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jiajia Wang, Minxia Hu, Qiang Zhu, Lanting Sun
Summary: This study aimed to explore the value of liver stiffness assessed by two-dimensional real-time shear wave elastography (2D-SWE) in predicting hypersplenism in Wilson's disease (WD) patients. The results showed that age, portal vein diameter, and liver stiffness were independent risk factors for hypersplenism in WD patients. The cutoff value of liver stiffness for predicting hypersplenism was 10.45 kPa, with a sensitivity of 75.9% and specificity of 73.8%. Dynamic monitoring of liver stiffness using 2D-SWE is crucial for the early diagnosis of hypersplenism in WD patients.
BMC MEDICAL IMAGING
(2022)
Article
Chemistry, Multidisciplinary
Yu Li, Qian Lv, Jiayue Dai, Ye Tian, Jianzhong Guo
Summary: A novel real-time curve tracing technique is proposed for accurate estimation of shear wave velocity, with experiments conducted in regions of different elasticity. Results show that the method has advantages in accuracy and anti-noise performance, and can better restore the shape of inclusions.
APPLIED SCIENCES-BASEL
(2021)
Article
Gastroenterology & Hepatology
Kento Imajo, Yasushi Honda, Takashi Kobayashi, Koki Nagai, Anna Ozaki, Michihiro Iwaki, Takaomi Kessoku, Yuji Ogawa, Hirokazu Takahashi, Yusuke Saigusa, Masato Yoneda, Hiroyuki Kirikoshi, Daisuke Utsunomiya, Shinichi Aishima, Satoru Saito, Atsushi Nakajima
Summary: MRE, VCTE, and 2D-SWE all demonstrated excellent diagnostic accuracy in detecting liver fibrosis in patients with NAFLD. MRE showed the highest diagnostic accuracy for stage 4 detection and intra- and inter-observer reproducibility.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)