标题
The Alternative Heart: Impact of Alternative Splicing in Heart Disease
作者
关键词
Alternative splicing, Molecular cardiology, Sarcomere, Cell signalling, Ion channels, Antisense oligonucleotides
出版物
Journal of Cardiovascular Translational Research
Volume 6, Issue 6, Pages 945-955
出版商
Springer Nature
发表日期
2013-06-18
DOI
10.1007/s12265-013-9482-z
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Dynamic Integration of Splicing within Gene Regulatory Pathways
- (2013) Ulrich Braunschweig et al. CELL
- Vascular Endothelial Cell Growth–Activated XBP1 Splicing in Endothelial Cells Is Crucial for Angiogenesis
- (2013) Lingfang Zeng et al. CIRCULATION
- HnRNP L and HnRNP A1 Induce Extended U1 snRNA Interactions with an Exon to Repress Spliceosome Assembly
- (2013) Ni-Ting Chiou et al. MOLECULAR CELL
- Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins
- (2012) Eric T. Wang et al. CELL
- Splice Modulating Therapies for Human Disease
- (2012) Pietro Spitali et al. CELL
- Understanding cardiovascular disease: a journey through the genome (and what we found there)
- (2012) E. Lara-Pezzi et al. Disease Models & Mechanisms
- Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction
- (2012) M. Touvron et al. Disease Models & Mechanisms
- TSUNAMI: an antisense method to phenocopy splicing-associated diseases in animals
- (2012) K. Sahashi et al. GENES & DEVELOPMENT
- Targeting nuclear RNA for in vivo correction of myotonic dystrophy
- (2012) Thurman M. Wheeler et al. NATURE
- Landscape of transcription in human cells
- (2012) Sarah Djebali et al. NATURE
- RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
- (2012) Wei Guo et al. NATURE MEDICINE
- Truncations of Titin Causing Dilated Cardiomyopathy
- (2012) Daniel S. Herman et al. NEW ENGLAND JOURNAL OF MEDICINE
- APPRIS: annotation of principal and alternative splice isoforms
- (2012) Jose Manuel Rodriguez et al. NUCLEIC ACIDS RESEARCH
- E-Peptides Control Bioavailability of IGF-1
- (2012) Marianne Smedegaard Hede et al. PLoS One
- Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues
- (2012) J. Merkin et al. SCIENCE
- The Evolutionary Landscape of Alternative Splicing in Vertebrate Species
- (2012) N. L. Barbosa-Morais et al. SCIENCE
- Pre-mRNA splicing in disease and therapeutics
- (2012) Ravi K. Singh et al. TRENDS IN MOLECULAR MEDICINE
- Manipulation of PK-M mutually exclusive alternative splicing by antisense oligonucleotides
- (2012) Z. Wang et al. Open Biology
- Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment
- (2012) Corinne Betts et al. Molecular Therapy-Nucleic Acids
- mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart
- (2011) Manlio Vinciguerra et al. AGING CELL
- Alternative splicing of T-box transcription factor genes
- (2011) Paige DeBenedittis et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- IGF-1Ea induces vessel formation after injury and mediates bone marrow and heart cross-talk through the expression of specific cytokines
- (2011) Maria Paola Santini et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Role of RBM25/LUC7L3 in Abnormal Cardiac Sodium Channel Splicing Regulation in Human Heart Failure
- (2011) Ge Gao et al. CIRCULATION
- Calcineurin Splicing Variant Calcineurin Aβ1 Improves Cardiac Function After Myocardial Infarction Without Inducing Hypertrophy
- (2011) Leanne E. Felkin et al. CIRCULATION
- A conserved splicing mechanism of the LMNA gene controls premature aging
- (2011) Isabel C. Lopez-Mejia et al. HUMAN MOLECULAR GENETICS
- Regulation of the Mutually Exclusive Exons 8a and 8 in the CaV1.2 Calcium Channel Transcript by Polypyrimidine Tract-binding Protein
- (2011) Zhen Zhi Tang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts
- (2011) Kan Cao et al. JOURNAL OF CLINICAL INVESTIGATION
- Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model
- (2011) Yimin Hua et al. NATURE
- Systemic Administration of PRO051 in Duchenne's Muscular Dystrophy
- (2011) Nathalie M. Goemans et al. NEW ENGLAND JOURNAL OF MEDICINE
- Comparative Analysis of mRNA Isoform Expression in Cardiac Hypertrophy and Development Reveals Multiple Post-Transcriptional Regulatory Modules
- (2011) Ji Yeon Park et al. PLoS One
- Antitumorigenic potential of STAT3 alternative splicing modulation
- (2011) F. Zammarchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly
- (2011) S. Cho et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2
- (2011) S. Sun et al. RNA
- Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging
- (2011) F. G. Osorio et al. Science Translational Medicine
- EH-myomesin splice isoform is a novel marker for dilated cardiomyopathy
- (2010) Roman Schoenauer et al. BASIC RESEARCH IN CARDIOLOGY
- Splice variants of Enigma homolog, differentially expressed during heart development, promote or prevent hypertrophy
- (2010) Tomoko Yamazaki et al. CARDIOVASCULAR RESEARCH
- Molecular and Functional Characterization of a Novel Cardiac-Specific Human Tropomyosin Isoform
- (2010) Sudarsan Rajan et al. CIRCULATION
- Heart Failure–Associated Changes in RNA Splicing of Sarcomere Genes
- (2010) Sek Won Kong et al. Circulation-Cardiovascular Genetics
- MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development
- (2010) A. Kalsotra et al. GENES & DEVELOPMENT
- X-box binding protein 1 regulates brain natriuretic peptide through a novel AP1/CRE-like element in cardiomyocytes
- (2010) Tamaki Sawada et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The Status of Exon Skipping as a Therapeutic Approach to Duchenne Muscular Dystrophy
- (2010) Qi-Long Lu et al. MOLECULAR THERAPY
- Deciphering the splicing code
- (2010) Yoseph Barash et al. NATURE
- Integrative Modeling Defines the Nova Splicing-Regulatory Network and Its Combinatorial Controls
- (2010) C. Zhang et al. SCIENCE
- Regulation of Alternative Splicing by Histone Modifications
- (2010) R. F. Luco et al. SCIENCE
- Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy
- (2009) T. Arimura et al. CARDIOVASCULAR RESEARCH
- The Spliceosome: Design Principles of a Dynamic RNP Machine
- (2009) Markus C. Wahl et al. CELL
- Evidence From Human Myectomy Samples That MYBPC3 Mutations Cause Hypertrophic Cardiomyopathy Through Haploinsufficiency
- (2009) Steven Marston et al. CIRCULATION RESEARCH
- SRp38 Regulates Alternative Splicing and Is Required for Ca2+ Handling in the Embryonic Heart
- (2009) Ying Feng et al. DEVELOPMENTAL CELL
- Functional Role of Transcriptional Factor TBX5 in Pre-mRNA Splicing and Holt-Oram Syndrome via Association with SC35
- (2009) Chun Fan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1
- (2009) Guey-Shin Wang et al. JOURNAL OF CLINICAL INVESTIGATION
- Mutations in Ribonucleic Acid Binding Protein Gene Cause Familial Dilated Cardiomyopathy
- (2009) Katharine M. Brauch et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Molecular Diversity of VEGF-A as a Regulator of Its Biological Activity
- (2009) Jeanette Woolard et al. MICROCIRCULATION
- Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome
- (2009) Claudio Hetz et al. MOLECULAR CELL
- RNA processing and its regulation: global insights into biological networks
- (2009) Donny D. Licatalosi et al. NATURE REVIEWS GENETICS
- CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA
- (2009) Young-Hwa Goo et al. NUCLEIC ACIDS RESEARCH
- Biodesign of a renal-protective peptide based on alternative splicing of B-type natriuretic peptide
- (2009) S. Pan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The protein factors MBNL1 and U2AF65 bind alternative RNA structures to regulate splicing
- (2009) M. B. Warf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow
- (2009) L. Zeng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reversal of RNA Dominance by Displacement of Protein Sequestered on Triplet Repeat RNA
- (2009) T. M. Wheeler et al. SCIENCE
- Distinct Expression and Function of Alternatively Spliced Tbx5 Isoforms in Cell Growth and Differentiation
- (2008) R. Georges et al. MOLECULAR AND CELLULAR BIOLOGY
- Alternative isoform regulation in human tissue transcriptomes
- (2008) Eric T. Wang et al. NATURE
- Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
- (2008) Qun Pan et al. NATURE GENETICS
- A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart
- (2008) A. Kalsotra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Splicing regulation: From a parts list of regulatory elements to an integrated splicing code
- (2008) Z. Wang et al. RNA
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