Coagulation, Protease-Activated Receptors, and Viral Myocarditis

PAR-1 contributes to the innate immune response during viral infection

(2013) Silvio Antoniak et al.   JOURNAL OF CLINICAL INVESTIGATION

The papain-like protease of porcine epidemic diarrhea virus negatively regulates type I interferon pathway by acting as a viral deubiquitinase

(2013) Y. Xing et al.   JOURNAL OF GENERAL VIROLOGY

Protease-Activated Receptor-2 Regulates the Innate Immune Response to Viral Infection in a Coxsackievirus B3–Induced Myocarditis

(2013) Alice Weithauser et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Platelet Biology and Receptor Pathways

(2013) Giovanni Cimmino et al.   Journal of Cardiovascular Translational Research

Tissue factor and glycoprotein C on herpes simplex virus type 1 are protease-activated receptor 2 cofactors that enhance infection

(2012) M. R. Sutherland et al.   BLOOD

β-Adrenergic Receptor Stimulation Transactivates Protease-Activated Receptor 1 via Matrix Metalloproteinase 13 in Cardiac Cells

(2012) Fabrice Jaffré et al.   CIRCULATION

An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats

(2012) Rink-Jan Lohman et al.   FASEB JOURNAL

Interferon-gamma-mediated tissue factor expression contributes to T-cell-mediated hepatitis through induction of hypercoagulation in mice

(2012) Junko Kato et al.   HEPATOLOGY

Naive T cells sense the cysteine protease allergen papain through protease-activated receptor 2 and propel TH2 immunity

(2012) Genqing Liang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Review: Viral infections and mechanisms of thrombosis and bleeding

(2012) M. Goeijenbier et al.   JOURNAL OF MEDICAL VIROLOGY

Interferon-Beta Improves Survival in Enterovirus-Associated Cardiomyopathy

(2012) Uwe Kühl et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Proteinase-Activated Receptor-4 Plays a Major Role in the Recruitment of Neutrophils Induced by Trypsin or Carrageenan during Pleurisy in Mice

(2012) L.F. Gomides et al.   PHARMACOLOGY

Sex-specific signaling through Toll-Like Receptors 2 and 4 contributes to survival outcome of Coxsackievirus B3 infection in C57Bl/6 mice

(2012) Brian J Roberts et al.   Biology of Sex Differences

Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response

(2011) Claudius Seitz et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Combating enterovirus replication: State-of-the-art on antiviral research

(2011) Hendrik Jan Thibaut et al.   BIOCHEMICAL PHARMACOLOGY

Th2 Regulation of Viral Myocarditis in Mice: Different Roles for TLR3 versus TRIF in Progression to Chronic Disease

(2011) Eric D. Abston et al.   Clinical & Developmental Immunology

The management of myocarditis

(2011) H.-P. Schultheiss et al.   EUROPEAN HEART JOURNAL

Viral myocarditis: potential defense mechanisms within the cardiomyocyte against virus infection

(2011) Toshitaka Yajima   Future Microbiology

Mast-Cell-Releasing Tryptase Triggers Acute Lung Injury Induced by Small Intestinal Ischemia–Reperfusion by Activating PAR-2 in Rats

(2011) Xiaoliang Gan et al.   INFLAMMATION

Protease-activated receptors and myocardial infarction

(2011) Silvio Antoniak et al.   IUBMB LIFE

TRIF Is a Critical Survival Factor in Viral Cardiomyopathy

(2011) A. Riad et al.   JOURNAL OF IMMUNOLOGY

Innate immunity and coagulation

(2011) C. T. ESMON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins

(2011) L. M. Sevigny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signal transduction by protease-activated receptors

(2010) Unice JK Soh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Up-regulation of ectopic trypsins in the myocardium by influenza A virus infection triggers acute myocarditis

(2010) Hai-Yan Pan et al.   CARDIOVASCULAR RESEARCH

Type B coxsackieviruses and their interactions with the innate and adaptive immune systems

(2010) Christopher C Kemball et al.   Future Microbiology

The effect on mortality of antipyretics in the treatment of influenza infection: systematic review and meta-analyis

(2010) Sally Eyers et al.   JOURNAL OF THE ROYAL SOCIETY OF MEDICINE

Modifications to the Hemagglutinin Cleavage Site Control the Virulence of a Neurotropic H1N1 Influenza Virus

(2010) X. Sun et al.   JOURNAL OF VIROLOGY

Myocarditis

(2010) Lori A. Blauwet et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Leukocyte Elastase Induces Lung Epithelial Apoptosis via a PAR-1–, NF-κB–, and p53-Dependent Pathway

(2009) Tomoko Suzuki et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Interferons and viral infections

(2009) Volker Fensterl et al.   BIOFACTORS

Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation

(2009) N. T. Funderburg et al.   BLOOD

Blockade of PAR1 Signaling with Cell-Penetrating Pepducins Inhibits Akt Survival Pathways in Breast Cancer Cells and Suppresses Tumor Survival and Metastasis

(2009) E. Yang et al.   CANCER RESEARCH

CXCL10 Inhibits Viral Replication Through Recruitment of Natural Killer Cells in Coxsackievirus B3-Induced Myocarditis

(2009) Ji Yuan et al.   CIRCULATION RESEARCH

Salicylates and Pandemic Influenza Mortality, 1918–1919 Pharmacology, Pathology, and Historic Evidence

(2009) Karen M. Starko   CLINICAL INFECTIOUS DISEASES

Platelet functions beyond hemostasis

(2009) S. S. SMYTH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Regulation of cardiomyocyte full-length tissue factor expression and microparticle release under inflammatory conditionsin vitro

(2009) S. ANTONIAK et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo

(2009) Q M Nhu et al.   Mucosal Immunology

Toll-Like Receptor 3 Signaling on Macrophages Is Required for Survival Following Coxsackievirus B4 Infection

(2009) Martin J. Richer et al.   PLoS One

Matrix Metalloproteinases in the Pathogenesis of Viral Heart Disease

(2009) David Marchant et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Toll-like receptors regulation of viral infection and disease☆

(2008) J THOMPSON et al.   ADVANCED DRUG DELIVERY REVIEWS

A key role for Toll-like receptor-3 in disrupting the hemostasis balance on endothelial cells

(2008) A. Shibamiya et al.   BLOOD

Mast Cells Play a Critical Role in the Pathogenesis of Viral Myocarditis

(2008) Hirokazu Higuchi et al.   CIRCULATION

Analysis of Proteinase-activated Receptor 2 and TLR4 Signal Transduction

(2008) Prasad Rallabhandi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-stranded polyinosinic acid oligonucleotides trigger leukocyte production of proteins belonging to fibrinolytic and coagulation cascades

(2008) Fariba Zare et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Viral myocarditis and coagulopathy: Increased tissue factor expression and plasma thrombogenicity

(2008) Silvio Antoniak et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The role of leucocytes in the acetyl salicylic acid (aspirin) induced nitric oxide synthesis in the production of interferon-α, a potent inhibitor of platelet aggregation and a thrombolytic agent

(2008) Mau Bhattacharyya et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Effective Chemokine Secretion by Dendritic Cells and Expansion of Cross-Presenting CD4-/CD8+ Dendritic Cells Define a Protective Phenotype in the Mouse Model of Coxsackievirus Myocarditis

(2008) A. O. Weinzierl et al.   JOURNAL OF VIROLOGY

The contribution of PARs to inflammation and immunity to fungi

(2008) S Moretti et al.   Mucosal Immunology

A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity

(2008) H. Negishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA