Level of macroautophagy drives senescent keratinocytes into cell death or neoplastic evasion

Identification of a gene signature of a pre-transformation process by senescence evasion in normal human epidermal keratinocytes

(2014) Nathalie Martin et al.   Molecular Cancer

Molecules and their functions in autophagy

(2012) Jong-Ok Pyo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Influence of the phosphodiesterase-5 inhibitor, sildenafil, on sensitivity to chemotherapy in breast tumor cells

(2010) Xu Di et al.   BREAST CANCER RESEARCH AND TREATMENT

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Autophagy mediates the process of cellular senescence characterizing bile duct damages in primary biliary cirrhosis

(2010) Motoko Sasaki et al.   LABORATORY INVESTIGATION

MnSOD Upregulation Induces Autophagic Programmed Cell Death in Senescent Keratinocytes

(2010) Emeric Deruy et al.   PLoS One

Senescent Keratinocytes Die by Autophagic Programmed Cell Death

(2009) Karo Gosselin et al.   AMERICAN JOURNAL OF PATHOLOGY

Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells

(2009) K. Gosselin et al.   CANCER RESEARCH

Autophagy mediates the mitotic senescence transition

(2009) A. R.J. Young et al.   GENES & DEVELOPMENT

Does autophagy have a license to kill mammalian cells?

(2008) F Scarlatti et al.   CELL DEATH AND DIFFERENTIATION

Frameshift mutations of autophagy-related genesATG2B, ATG5, ATG9BandATG12in gastric and colorectal cancers with microsatellite instability

(2008) Mi Ran Kang et al.   JOURNAL OF PATHOLOGY

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

(2008) Eisuke Itakura et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE