Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2

Disruption of Thioredoxin Reductase 1 Protects Mice from Acute Acetaminophen-Induced Hepatotoxicity through Enhanced NRF2 Activity

(2013) Andrew D. Patterson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Reactive oxygen species generated in different compartments induce cell death, survival, or senescence

(2013) Emiliano Panieri et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thioredoxin-interacting Protein Mediates High Glucose-induced Reactive Oxygen Species Generation by Mitochondria and the NADPH Oxidase, Nox4, in Mesangial Cells

(2013) Anu Shah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-  receptor tyrosine kinase signaling

(2013) M. Dagnell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thioredoxin Reductase Inhibition Elicits Nrf2-Mediated Responses in Clara Cells: Implications for Oxidant-Induced Lung Injury

(2012) Morgan L. Locy et al.   ANTIOXIDANTS & REDOX SIGNALING

Thiophosphate and selenite conversely modulate cell death induced by glutathione depletion or cisplatin: effects related to activity and Sec contents of thioredoxin reductase

(2012) Xiaoxiao Peng et al.   BIOCHEMICAL JOURNAL

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Glutathione and Glutaredoxin Act as a Backup of Human Thioredoxin Reductase 1 to Reduce Thioredoxin 1 Preventing Cell Death by Aurothioglucose

(2012) Yatao Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pyrroloquinoline quinone modulates the kinetic parameters of the mammalian selenoprotein thioredoxin reductase 1 and is an inhibitor of glutathione reductase

(2011) Jianqiang Xu et al.   BIOCHEMICAL PHARMACOLOGY

Cysteine mutant of mammalian GPx4 rescues cell death induced by disruption of the wild-type selenoenzyme

(2011) Alexander M. Mannes et al.   FASEB JOURNAL

Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes

(2011) Xu Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1

(2011) Justin R. Prigge et al.   FREE RADICAL BIOLOGY AND MEDICINE

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

Loss of Thioredoxin Reductase 1 Renders Tumors Highly Susceptible to Pharmacologic Glutathione Deprivation

(2010) P. K. Mandal et al.   CANCER RESEARCH

System xc−and Thioredoxin Reductase 1 Cooperatively Rescue Glutathione Deficiency

(2010) Pankaj Kumar Mandal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell Density Plays a Critical Role in Ex Vivo Expansion of T Cells for Adoptive Immunotherapy

(2010) Qiangzhong Ma et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Hepatocytes lacking thioredoxin reductase 1 have normal replicative potential during development and regeneration

(2010) M. F. Rollins et al.   JOURNAL OF CELL SCIENCE

Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery

(2010) X.-M. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling

(2010) E. W. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Focus on mammalian thioredoxin reductases — Important selenoproteins with versatile functions

(2009) Elias S.J. Arnér   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Penultimate selenocysteine residue replaced by cysteine in thioredoxin reductase from selenium-deficient rat liver

(2009) Jun Lu et al.   FASEB JOURNAL

High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy

(2009) Sofi E. Eriksson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cytoprotective Nrf2 Pathway Is Induced In Chronically Txnrd 1-Deficient Hepatocytes

(2009) Elena S. Suvorova et al.   PLoS One

The Role of Thioredoxin Reductases in Brain Development

(2008) Jonna Soerensen et al.   PLoS One