The adaptor protein FADD and the initiator caspase-8 mediate activation of NF-κB by TRAIL

TNFR1-induced activation of the classical NF-κB pathway

(2011) Harald Wajant et al.   FEBS Journal

TRADD is critical for resistance to TRAIL-induced cell death through NF-κB activation

(2011) Joo-Young Kim et al.   FEBS LETTERS

Cellular FLICE-inhibitory Protein (cFLIP) Isoforms Block CD95- and TRAIL Death Receptor-induced Gene Induction Irrespective of Processing of Caspase-8 or cFLIP in the Death-inducing Signaling Complex

(2011) Shyam M. Kavuri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

(2011) William J. Kaiser et al.   NATURE

Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

(2011) Andrew Oberst et al.   NATURE

The role of TRADD in TRAIL-induced apoptosis and signaling

(2010) Xiumei Cao et al.   FASEB JOURNAL

Dynamics within the CD95 death-inducing signaling complex decide life and death of cells

(2010) Leo Neumann et al.   Molecular Systems Biology

New insights into apoptosis signaling by Apo2L/TRAIL

(2010) F Gonzalvez et al.   ONCOGENE

Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

(2009) Andrew Kovalenko et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pursuing different ‘TRADDes’: TRADD signaling induced by TNF-receptor 1 and the Epstein-Barr virus oncoprotein LMP1

(2008) Arnd Kieser   BIOLOGICAL CHEMISTRY

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced chemokine release in both TRAIL-resistant and TRAIL-sensitive cells via nuclear factor kappa B

(2008) Wanhu Tang et al.   FEBS Journal

The Viral Oncoprotein LMP1 Exploits TRADD for Signaling by Masking Its Apoptotic Activity

(2008) Frank Schneider et al.   PLOS BIOLOGY