Role of the promyelocytic leukaemia protein in cell death regulation

The role of PML in the control of apoptotic cell fate: a new key player at ER–mitochondria sites

(2011) P Pinton et al.   CELL DEATH AND DIFFERENTIATION

p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53

(2011) G Melino   CELL DEATH AND DIFFERENTIATION

p63, a Story of Mice and Men

(2011) Hans Vanbokhoven et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

p73: A Multifunctional Protein in Neurobiology

(2011) Richard Killick et al.   MOLECULAR NEUROBIOLOGY

PAX5–PML acts as a dual dominant-negative form of both PAX5 and PML

(2011) S Kurahashi et al.   ONCOGENE

Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants

(2011) C R Reis et al.   Cell Death & Disease

p73 regulates maintenance of neural stem cell

(2010) Massimiliano Agostini et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PML/RARA Oxidation and Arsenic Binding Initiate the Antileukemia Response of As2O3

(2010) Marion Jeanne et al.   CANCER CELL

PML: A tumor suppressor that regulates cell fate in mammary gland

(2010) Wenjing Li et al.   CELL CYCLE

ΔNp63 is an ectodermal gatekeeper of epidermal morphogenesis

(2010) R Shalom-Feuerstein et al.   CELL DEATH AND DIFFERENTIATION

Negative regulation of autophagy

(2010) C Liang   CELL DEATH AND DIFFERENTIATION

Autophagy for tissue homeostasis and neuroprotection

(2010) Guillermo Mariño et al.   CURRENT OPINION IN CELL BIOLOGY

New plays in the p53 theater

(2010) Yael Aylon et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Role of the SUMO-interacting motif in HIPK2 targeting to the PML nuclear bodies and regulation of p53

(2010) Ki Sa Sung et al.   EXPERIMENTAL CELL RESEARCH

PML Regulates Apoptosis at Endoplasmic Reticulum by Modulating Calcium Release

(2010) C. Giorgi et al.   SCIENCE

p63 and p73, the Ancestors of p53

(2010) V. Dotsch et al.   Cold Spring Harbor Perspectives in Biology

Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid

(2010) S Schneider-Jakob et al.   Cell Death & Disease

Phosphorylation of Puma modulates its apoptotic function by regulating protein stability

(2010) M Fricker et al.   Cell Death & Disease

Potent antitumoral activity of TRAIL through generation of tumor-targeted single-chain fusion proteins

(2010) B Schneider et al.   Cell Death & Disease

Drosophila happyhour modulates JNK-dependent apoptosis

(2010) D Lam et al.   Cell Death & Disease

Mitochondrial translocation of oxidized cofilin induces caspase-independent necrotic-like programmed cell death of T cells

(2010) G H Wabnitz et al.   Cell Death & Disease

Role of the JNK/c-Jun/AP-1 signaling pathway in galectin-1-induced T-cell death

(2010) B Brandt et al.   Cell Death & Disease

c-Abl phosphorylation of ΔNp63α is critical for cell viability

(2010) M Yuan et al.   Cell Death & Disease

Activation of mTOR coincides with autophagy during ligation-induced atrophy in the rat submandibular gland

(2010) N Silver et al.   Cell Death & Disease

c-Abl downregulates the slow phase of double-strand break repair

(2010) V Meltser et al.   Cell Death & Disease

Palmitoylation of human FasL modulates its cell death-inducing function

(2010) F Guardiola-Serrano et al.   Cell Death & Disease

Linking calorie restriction to longevity through sirtuins and autophagy: any role for TOR

(2010) M V Blagosklonny   Cell Death & Disease

The novel estrogen-induced gene EIG121 regulates autophagy and promotes cell survival under stress

(2010) L Deng et al.   Cell Death & Disease

Bcl-2 antagonists and cancer: from the clinic, back to the bench

(2010) M Degli Esposti   Cell Death & Disease

MEK–ERK-dependent multiple caspase activation by mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma cell death

(2010) A Tomiyama et al.   Cell Death & Disease

Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation

(2010) C E Barton et al.   Cell Death & Disease

p73 deficiency results in impaired self renewal and premature neuronal differentiation of mouse neural progenitors independently of p53

(2010) L Gonzalez-Cano et al.   Cell Death & Disease

Negative regulation of UCP2 by TGFβ signaling characterizes low and intermediate-grade primary breast cancer

(2010) A Sayeed et al.   Cell Death & Disease

Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemia

(2010) Q Li et al.   Cell Death & Disease

p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma

(2010) D Meley et al.   Cell Death & Disease

The C-terminus of p63 contains multiple regulatory elements with different functions

(2010) W E Straub et al.   Cell Death & Disease

Intracellular Ca2+ release through ryanodine receptors contributes to AMPA receptor-mediated mitochondrial dysfunction and ER stress in oligodendrocytes

(2010) A Ruiz et al.   Cell Death & Disease

IGF1 activates cell cycle arrest following irradiation by reducing binding of ΔNp63 to the p21 promoter

(2010) G C Mitchell et al.   Cell Death & Disease

XIAP impairs Smac release from the mitochondria during apoptosis

(2010) L Flanagan et al.   Cell Death & Disease

Caspase cleavage of the Golgi stacking factor GRASP65 is required for Fas/CD95-mediated apoptosis

(2010) J P X Cheng et al.   Cell Death & Disease

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

(2010) E Morselli et al.   Cell Death & Disease

Pro-apoptotic Bax is the major and Bak an auxiliary effector in cytokine deprivation-induced mast cell apoptosis

(2010) M Karlberg et al.   Cell Death & Disease

JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis

(2010) V Tomlinson et al.   Cell Death & Disease

Mechanisms of HIV-associated lymphocyte apoptosis: 2010

(2010) N W Cummins et al.   Cell Death & Disease

GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy

(2010) N Heidari et al.   Cell Death & Disease

Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK

(2010) F McCoy et al.   Cell Death & Disease

Autophagy as the main means of cytotoxicity by glucocorticoids in hematological malignancies

(2009) Dan Grandér et al.   Autophagy

Stemming out of a new PML era?

(2009) P Salomoni   CELL DEATH AND DIFFERENTIATION

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

(2009) E Laane et al.   CELL DEATH AND DIFFERENTIATION

53BP1 represses mitotic catastrophe in syncytia elicited by the HIV-1 envelope

(2009) J-L Perfettini et al.   CELL DEATH AND DIFFERENTIATION

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

A novel signaling network as a critical rheostat for the biology and maintenance of the normal stem cell and the cancer-initiating cell

(2009) Keisuke Ito et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

SnoN functions as a tumour suppressor by inducing premature senescence

(2009) Deng Pan et al.   EMBO JOURNAL

Following TRAIL’s path in the immune system

(2009) Christina Falschlehner et al.   IMMUNOLOGY

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

(2009) Andrea Viale et al.   NATURE

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

The tumor suppressor Pml regulates cell fate in the developing neocortex

(2009) Tarik Regad et al.   NATURE NEUROSCIENCE

PML involvement in the p73-mediated E1A-induced suppression of EGFR and induction of apoptosis in head and neck cancers

(2009) P Klanrit et al.   ONCOGENE

PML depletion disrupts normal mammary gland development and skews the composition of the mammary luminal cell progenitor pool

(2009) W. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The tumor suppressor protein PML controls apoptosis induced by the HIV-1 envelope

(2008) J-L Perfettini et al.   CELL DEATH AND DIFFERENTIATION

Control of autophagy by oncogenes and tumor suppressor genes

(2008) M C Maiuri et al.   CELL DEATH AND DIFFERENTIATION

New insights into the role of PML in tumour suppression

(2008) P Salomoni et al.   CELL RESEARCH

Identification of PCTA, a TGIF antagonist that promotes PML function in TGF-β signalling

(2008) Nourdine Faresse et al.   EMBO JOURNAL

The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2–DAXX–HAUSP complex

(2008) Min Sup Song et al.   EMBO JOURNAL

Kinase-Inactivated ULK Proteins Inhibit Autophagy via Their Conserved C-Terminal Domains Using an Atg13-Independent Mechanism

(2008) E. Y. W. Chan et al.   MOLECULAR AND CELLULAR BIOLOGY

YAP and p73: A Complex Affair

(2008) Julian Downward et al.   MOLECULAR CELL

PML, YAP, and p73 Are Components of a Proapoptotic Autoregulatory Feedback Loop

(2008) Eleonora Lapi et al.   MOLECULAR CELL

The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network

(2008) Min Sup Song et al.   NATURE

PML targeting eradicates quiescent leukaemia-initiating cells

(2008) Keisuke Ito et al.   NATURE

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

Directing cancer cells to self-destruct with pro-apoptotic receptor agonists

(2008) Avi Ashkenazi   NATURE REVIEWS DRUG DISCOVERY

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE

The impact of p53 and p73 on aneuploidy and cancer

(2008) Richard Tomasini et al.   TRENDS IN CELL BIOLOGY