Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1

Activation of a unique p53-dependent DNA damage response

(2010) Jun Yang et al.   CELL CYCLE

Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo

(2010) Hiroyuki Niida et al.   EMBO JOURNAL

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Chk1 promotes replication fork progression by controlling replication initiation

(2010) E. Petermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MDM2-Dependent Downregulation of p21 and hnRNP K Provides a Switch between Apoptosis and Growth Arrest Induced by Pharmacologically Activated p53

(2009) Martin Enge et al.   CANCER CELL

Targeting the hypoxia-inducible factor (HIF) pathway in cancer

(2009) Evon Poon et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Small-Molecule Activation of p53 Blocks Hypoxia-Inducible Factor 1  and Vascular Endothelial Growth Factor Expression In Vivo and Leads to Tumor Cell Apoptosis in Normoxia and Hypoxia

(2009) J. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE