Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases

Environmental Novelty Activates β2-Adrenergic Signaling to Prevent the Impairment of Hippocampal LTP by Aβ Oligomers

(2013) Shaomin Li et al.   NEURON

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Wnt Signaling: Role in Alzheimer Disease and Schizophrenia

(2012) Nibaldo C. Inestrosa et al.   Journal of Neuroimmune Pharmacology

The Secreted Wnt Antagonist Dickkopf-1 Is Required for Amyloid  -Mediated Synaptic Loss

(2012) S. A. Purro et al.   JOURNAL OF NEUROSCIENCE

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway

(2012) R Killick et al.   MOLECULAR PSYCHIATRY

Wnt-5a Is a Synaptogenic Factor with Neuroprotective Properties against Aß Toxicity

(2012) Lorena Varela-Nallar et al.   Neurodegenerative Diseases

Wnt Signaling in the Vertebrate Central Nervous System: From Axon Guidance to Synaptic Function

(2012) P. C. Salinas   Cold Spring Harbor Perspectives in Biology

Wnt Signaling in Neuromuscular Junction Development

(2012) K. Koles et al.   Cold Spring Harbor Perspectives in Biology

Wnt signaling during synaptic development and plasticity

(2011) Vivian Budnik et al.   CURRENT OPINION IN NEUROBIOLOGY

Soluble Aβ oligomer production and toxicity

(2011) Megan E. Larson et al.   JOURNAL OF NEUROCHEMISTRY

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

(2011) Sergio T. Ferreira et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

β-Adducin Is Required for Stable Assembly of New Synapses and Improved Memory upon Environmental Enrichment

(2011) Ewa Bednarek et al.   NEURON

Wnt7a signaling promotes dendritic spine growth and synaptic strength through Ca2+/Calmodulin-dependent protein kinase II

(2011) L. Ciani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's Disease

(2011) D. J. Selkoe   Cold Spring Harbor Perspectives in Biology

Dysfunction and recovery of synapses in prion disease: implications for neurodegeneration

(2010) Julie A. Moreno et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis

(2010) M. Sahores et al.   DEVELOPMENT

Wnt-5a Modulates Recycling of Functional GABAA Receptors on Hippocampal Neurons

(2010) L. Cuitino et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses

(2010) L. Varela-Nallar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease

(2010) Austen J. Milnerwood et al.   TRENDS IN NEUROSCIENCES

Guidance Molecules in Synapse Formation and Plasticity

(2010) K. Shen et al.   Cold Spring Harbor Perspectives in Biology

Nurturing brain plasticity: impact of environmental enrichment

(2009) L Baroncelli et al.   CELL DEATH AND DIFFERENTIATION

Wnt-5a/JNK Signaling Promotes the Clustering of PSD-95 in Hippocampal Neurons

(2009) Ginny G. Farías et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dkk-3 is elevated in CSF and plasma of Alzheimer’s disease patients

(2009) Christoph Zenzmaier et al.   JOURNAL OF NEUROCHEMISTRY

Increased Dickkopf-1 expression in transgenic mouse models of neurodegenerative disease

(2009) Maria Cristina Rosi et al.   JOURNAL OF NEUROCHEMISTRY

Alzheimer's disease: synaptic dysfunction and Aβ

(2009) Ganesh M Shankar et al.   Molecular Neurodegeneration

Emerging roles of Wnts in the adult nervous system

(2009) Nibaldo C. Inestrosa et al.   NATURE REVIEWS NEUROSCIENCE

Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function

(2009) Lorena Varela-Nallar et al.   Neural Development

Wnt Signaling Mediates Experience-Related Regulation of Synapse Numbers and Mossy Fiber Connectivities in the Adult Hippocampus

(2009) Nadine Gogolla et al.   NEURON

Ror1-Ror2 complexes modulate synapse formation in hippocampal neurons

(2009) S. Paganoni et al.   NEUROSCIENCE

Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics

(2009) Ling Lin et al.   TRENDS IN NEUROSCIENCES

Amyloid-β Binds to the Extracellular Cysteine-rich Domain of Frizzled and Inhibits Wnt/β-Catenin Signaling

(2008) Margaret H. Magdesian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnt Regulates Axon Behavior through Changes in Microtubule Growth Directionality: A New Role for Adenomatous Polyposis Coli

(2008) S. A. Purro et al.   JOURNAL OF NEUROSCIENCE

Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation

(2008) Elizabeth K Davis et al.   Neural Development