期刊
JOURNAL OF MOLECULAR CELL BIOLOGY
卷 2, 期 4, 页码 176-177出版社
OXFORD UNIV PRESS
DOI: 10.1093/jmcb/mjq014
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Neutrophils constitute the first line of defense against invading pathogens, but they also are responsible for tissue destruction in pathological conditions. In a recent paper published in Science Signaling, Junger and colleagues show that adenosine 5'-triphosphate release and signaling through purinergic P2 receptors upon neutrophil activation by bacterial and inflammatory stimuli represents an important mechanism for effective neutrophil functional response and host protection.
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