Article
Oncology
Tarik Bajri, Peter Kornprat, Florian Faschinger, Georg Werkgartner, Hans Jorg Mischinger, Doris Wagner
Summary: Sarcopenia is more prevalent in right-sided colorectal cancer patients and is associated with higher rates of postoperative complications and mortality related to cancer. Sarcopenia is independently associated with worse overall survival and disease-free survival.
Review
Oncology
Alexandra Nassar, Stylianos Tzedakis, Alix Dhote, Marie Strigalev, Romain Coriat, Mehdi Karoui, Anthony Dohan, Martin Gaillard, Ugo Marchese, David Fuks
Summary: This literature review aimed to assess the feasibility of laparoscopic liver resection for multiple colorectal liver metastases. The minimally invasive approach for liver cancer has become a new standard of oncological care, and laparoscopic liver resection is a significant indication for multiple colorectal liver metastases. The purpose of this paper was to highlight the novelty and updates in the field of multiple minimally invasive liver resections and discuss the feasibility and outcomes of laparoscopic concomitant multiple liver resections for colorectal liver metastases.
Article
Oncology
Colm Neary, Lukas O'Brien, Emilie McCormack, Michael Kelly, Jarlath Bolger, Gerard McEntee, John Conneely
Summary: This study aims to define textbook outcomes (TBO) specific to surgical resection of colorectal liver metastases and investigate their impact on survival. The analysis of all liver resections performed at their center from 2009 to 2020 revealed that major morbidity was the major limiting factor in not achieving a TBO. Achieving a TBO was associated with a significant improvement in survival.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Gastroenterology & Hepatology
Elena Panettieri, Bradford J. Kim, Yoshikuni Kawaguchi, Francesco Ardito, Caterina Mele, Agostino Maria De Rose, Maria Vellone, Yun Shin Chun, Ching-Wei D. Tzeng, Thomas A. Aloia, Felice Giuliante, Jean-Nicolas Vauthey
Summary: The ability to undergo resection of recurrence after curative hepatectomy for colorectal liver metastases is associated with improved survival. The number and sites of resections of recurrence impact survival.
JOURNAL OF GASTROINTESTINAL SURGERY
(2022)
Article
Oncology
Florian E. Buisman, Daniele Giardiello, Nancy E. Kemeny, Ewout W. Steyerberg, Diederik J. Hoppener, Boris Galjart, Pieter M. H. Nierop, Vinod P. Balachandran, Andrea Cercek, Jeffrey A. Drebin, Mithat Gonen, William R. Jarnagin, T. P. Kingham, Peter B. Vermeulen, Alice C. Wei, Dirk J. Grunhagen, Cornelis Verhoef, Micheal D'Angelica, Bas Groot Koerkamp
Summary: This study aimed to develop a prediction model for 10-year overall survival (OS) after resection of colorectal liver metastasis (CRLM) based on patient, tumor, and treatment characteristics. The prediction model included 15 independent prognostic factors and demonstrated good discrimination and calibration. The web-based calculator developed in this study can be used to inform patients and serve as a benchmark for evaluating the prognostic value of novel biomarkers.
EUROPEAN JOURNAL OF CANCER
(2022)
Article
Surgery
Christian Hobeika, Ecoline Tribillon, Ugo Marchese, Nicole Faermark, Abdessalem Ghedira, Stephane Bonnet, Alexandra Nassar, Brice Gayet, David Fuks
Summary: The study found that the Institut Mutualiste Montsouris classification is a valuable difficulty scoring system for laparoscopic repeat liver resections procedures. Additionally, previous major resection and presence of sinusoidal obstruction syndrome are independent risk factors of unexpected difficulty.
Article
Oncology
Wiebke Rodieck, Michael Hallensleben, Julia Robert, Oliver Beetz, Gerrit Grannas, Sebastian Cammann, Felix Oldhafer, Juergen Klempnauer, Florian W. R. Vondran, Ulf Kulik
Summary: This study analyzed 727 cases of liver resection for colorectal liver metastases and found that perioperative blood transfusions have a negative impact on postoperative renal function and overall survival.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Gastroenterology & Hepatology
Michael R. Driedger, Thomas S. Yamashita, Patrick Starlinger, Kellie L. Mathis, Rory L. Smoot, Sean P. Cleary, David M. Nagorney
Summary: The concurrent resection of primary cancer and synchronous colorectal cancer liver metastases (CRCLM) may lead to increased morbidity and mortality, especially in patients undergoing major liver/major colorectal resections. Postoperative complications may result in the inability to receive adjuvant chemotherapy, which could impact survival outcomes.
Article
Gastroenterology & Hepatology
Sulaiman Nanji, Zuhaib M. Mir, Safiya Karim, Kelly E. Brennan, Sunil Patel, Shaila J. Merchant, Christopher M. Booth
Summary: Perioperative blood transfusion is common in patients undergoing resection of CRLM, and is associated with longer hospital stay, higher mortality, readmission rates, and inferior 5-year survival. However, excluding early postoperative deaths, blood transfusion does not appear to be independently associated with survival outcomes.
Article
Oncology
Rohin Gawdi, Cristian D. Valenzuela, Omeed Moaven, John A. Stauffer, Nico R. Del Piccolo, Tanto Cheung, Carlos U. Corvera, Andrew D. Wisneski, Charles Cha, Perry Shen, Greg Russell, Nima Zarandi, Justin Dourado
Summary: This study examined the impact of neoadjuvant, adjuvant, and perioperative chemotherapy on the outcomes of patients with resectable colorectal-liver metastases (CLM). The results showed that adjuvant and perioperative chemotherapy were independently associated with improved overall survival (OS) compared to surgery alone.
JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Medicine, General & Internal
Hiroaki Nozawa, Takeaki Ishizawa, Hideo Yasunaga, Hiroaki Ishii, Hirofumi Sonoda, Shigenobu Emoto, Koji Murono, Kazuhito Sasaki, Kazushige Kawai, Nobuhisa Akamatsu, Junichi Kaneko, Junichi Arita, Kiyoshi Hasegawa, Soichiro Ishihara
Summary: This study retrospectively analyzed patients with primary colorectal cancer and liver metastases who underwent one-stage resection with different approaches. The laparoscopic groups had smaller blood loss and shorter hospital stays compared to the open surgery group. However, postoperative complication rates and survival outcomes were similar among the groups.
Article
Oncology
Andrew A. Gumbs, Eric Lorenz, Tzu-Jung Tsai, Lee Starker, Joe Flanagan, Andrea Benedetti Cacciaguerra, Ng Jing Yu, Melinda Bajul, Elie Chouillard, Roland Croner, Mohammad Abu Hilal
Summary: This study examined the short-term outcomes of minimally invasive liver resection for patients with colorectal liver metastases. The results suggest that laparoscopic and robotic approaches may have advantages over open hepatectomy in terms of blood loss, hospital stay, and morbidity rates.
Article
Oncology
Tobias S. Schiergens, Moritz Drefs, Maximilian Doersch, Florian Kuehn, Markus Albertsmeier, Hanno Niess, Markus B. Schoenberg, Matthias Assenmacher, Helmut Kuechenhoff, Wolfgang E. Thasler, Markus O. Guba, Martin K. Angele, Markus Rentsch, Jens Werner, Joachim Andrassy
Summary: The use of pedicle clamping during liver resection for colorectal cancer liver metastases showed favorable long-term outcomes and lower rates of increased transfusion demand without increasing postoperative morbidity. Further prospective evaluation is needed to fully understand the potential oncologic benefits of this technique for patients undergoing curative resection.
Article
Surgery
Davit L. Aghayan, Gabriella d'Albenzio, Asmund A. Fretland, Egidijus Pelanis, Bard I. Rosok, Sheraz Yaqub, Rafael Palomar, Bjorn Edwin
Summary: This study aimed to evaluate the surgical and oncologic safety of laparoscopic parenchyma-sparing liver resection for large colorectal metastases. The results showed satisfactory short and long-term outcomes for patients with large colorectal liver metastases, with no impact of tumor size on survival.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Oncology
Fabio Procopio, Matteo Cimino, Flavio Milana, Eloisa Franchi, Bruno Branciforte, Guido Torzilli
Summary: This study demonstrates the feasibility of laparoscopic resection for colorectal liver metastases involving the hepatic vein at the caval confluence. It provides technical tricks for achieving parenchyma-sparing surgery in laparoscopy.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Gastroenterology & Hepatology
Bobby Tingstedt, Bodil Andersson, Claes Jonsson, Victoria Formichov, Svein-Olav Bratlie, Mikael Ohman, Britt-Marie Karlsson, Christophe Ansorge, Ralf Segersvard, Thomas Gasslander
Article
Gastroenterology & Hepatology
Jenny Rystedt, Bobby Tingstedt, Christoph Ansorge, Johan Nilsson, Bodil Andersson
Article
Gastroenterology & Hepatology
Daniel Akerberg, Daniel Ansari, Magnus Bergenfeldt, Roland Andersson, Bobby Tingstedt
Article
Surgery
E. Sahlstrom, J. Nilsson, B. Tingstedt, M. Bergenfeldt, R. Andersson, B. Andersson
Summary: This study described patients with pancreatic and periampullary cancers who were found unresectable during surgery, which was associated with a poor prognosis. Although the frequency of unresectability did not decrease during the study period, palliative surgical procedures became less common.
SCANDINAVIAN JOURNAL OF SURGERY
(2021)
Editorial Material
Surgery
Martin Almquist, Bobby Tingstedt
Article
Pediatrics
Anahid Teimourian, Felipe Donoso, Pernilla Stenstrom, Helena Arnadottir, Einar Arnbjornsson, Helene Lilja, Martin Salo
Article
Surgery
Tara M. Mackay, Elizabeth M. Gleeson, Ulrich F. Wellner, Caroline Williamsson, Olivier R. Busch, Bas Groot Koerkamp, Tobias Keck, Hjalmar C. van Santvoort, Bobby Tingstedt, Henry A. Pitt, Marc G. Besselink
Summary: This study compared pancreatic surgery registries from four Western countries and found significant differences in design, variables collected, patient characteristics, treatment strategies, and outcomes.
Article
Surgery
C. Williamsson, K. Stenvall, J. Wennerblom, R. Andersson, B. Andersson, B. Tingstedt
WORLD JOURNAL OF SURGERY
(2020)
Article
Surgery
Anouk E. J. Latenstein, Tara M. Mackay, Joal D. Beane, Olivier R. Busch, Susan van Dieren, Elizabeth M. Gleeson, Bas Groot Koerkamp, Hjalmar C. van Santvoort, Ulrich F. Wellner, Caroline Williamsson, Bobby Tingstedt, Tobias Keck, Henry A. Pitt, Marc G. Besselink
Summary: This study compared the use and postoperative outcomes of total pancreatectomy among 4 Western countries and found significant differences. Variations in the ratio of total pancreatectomy to pancreatoduodenectomy, patient characteristics, major morbidity, and in-hospital mortality were noted among these countries. Further research is needed to explain and ultimately improve patient outcomes.
Article
Surgery
Elizabeth M. Gleeson, Henry A. Pitt, Tara. M. Mackay, Ulrich F. Wellner, Caroline Williamsson, Olivier R. Busch, Bas Groot Koerkamp, Tobias Keck, Hjalmar C. van Santvoort, Bobby Tingstedt, Marc G. Besselink
Summary: This study aimed to compare failure to rescue (FTR) after pancreatoduodenectomy between North America and Northern Europe. The results showed differences in complication rates and FTR between patients in North America and Northern Europe, with factors such as age and severity of systemic diseases contributing to FTR.
Article
Surgery
Martin Salo, Linda Bonnor, Christina Graneli, Pernilla Stenstrom, Magnus Anderberg
Summary: This study evaluated a decade of pediatric robotic surgery and found that despite low volume of surgeries, operative times and conversion rates are continuously decreasing.
INTERNATIONAL JOURNAL OF MEDICAL ROBOTICS AND COMPUTER ASSISTED SURGERY
(2022)
Review
Gastroenterology & Hepatology
Rupaly Pande, James M. Halle-Smith, Liam Phelan, Thomas Thorne, M. Panikkar, James Hodson, Keith J. Roberts
Summary: This study aimed to assess the clinical validity of externally validated risk scores for postoperative pancreatic fistula (POPF). The results showed that most risk scores lack external validation, and the verified scores have limited predictive accuracy. Consensus is needed to determine which score to use in clinical practice.
Article
Medicine, General & Internal
Adam Zeyara, Bobby Tingstedt, Bodil Andersson
Summary: Mortality after elective pancreatic surgery is low, but morbidity remains high. Late postpancreatectomy hemorrhage is a rare but potentially lethal complication, with difficulties in identifying the bleeding source highlighted in this case.
JOURNAL OF MEDICAL CASE REPORTS
(2021)
Article
Surgery
J. Wennerblom, Z. Ateeb, C. Jonsson, B. Bjornsson, B. Tingstedt, C. Williamsson, P. Sandstrom, C. Ansorge, J. Blomberg, M. Del Chiaro
Summary: The use of biodegradable reinforcement at the transection line of the pancreas did not reduce postoperative pancreatic fistula compared to regular stapler transection in distal pancreatectomy. Additionally, there was no significant difference in postoperative complications and duration of hospital stay between the two groups.
BRITISH JOURNAL OF SURGERY
(2021)
Article
Pediatrics
Martin Salo
PEDIATRIC GASTROENTEROLOGY HEPATOLOGY & NUTRITION
(2019)