Contemporary Avian Influenza A Virus Subtype H1, H6, H7, H10, and H15 Hemagglutinin Genes Encode a Mammalian Virulence Factor Similar to the 1918 Pandemic Virus H1 Hemagglutinin

Circulating Avian Influenza Viruses Closely Related to the 1918 Virus Have Pandemic Potential

(2014) Tokiko Watanabe et al.   Cell Host & Microbe

Emergence in China of human disease due to avian influenza A(H10N8) – Cause for concern?

(2014) Kelvin K.W. To et al.   JOURNAL OF INFECTION

H6 Influenza Viruses Pose a Potential Threat to Human Health

(2014) G. Wang et al.   JOURNAL OF VIROLOGY

Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study

(2014) HaiYing Chen et al.   LANCET

Poultry carrying H9N2 act as incubators for novel human avian influenza viruses

(2014) Di Liu et al.   LANCET

Changes in microRNA and mRNA Expression with Differentiation of Human Bronchial Epithelial Cells

(2013) Asuncion Martinez-Anton et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Outbreak of Variant Influenza A(H3N2) Virus in the United States

(2013) M. A. Jhung et al.   CLINICAL INFECTIOUS DISEASES

Treatment with the reactive oxygen species scavenger EUK-207 reduces lung damage and increases survival during 1918 influenza virus infection in mice

(2013) John C. Kash et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome

(2013) Yu Chen et al.   LANCET

Genomic signature and protein sequence analysis of a novel influenza A (H7N9) virus that causes an outbreak in humans in China

(2013) Qi Liu et al.   MICROBES AND INFECTION

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

H7N9 Avian Influenza A Virus and the Perpetual Challenge of Potential Human Pandemicity

(2013) D. M. Morens et al.   mBio

To dream the impossible dream: universal influenza vaccination

(2013) Jonathan W Yewdell   Current Opinion in Virology

Human infection with avian influenza A H6N1 virus: an epidemiological analysis

(2013) Sung-Hsi Wei et al.   Lancet Respiratory Medicine

High-throughput RNA sequencing of a formalin-fixed, paraffin-embedded autopsy lung tissue sample from the 1918 influenza pandemic

(2012) Yong-Li Xiao et al.   JOURNAL OF PATHOLOGY

Analysis by Single-Gene Reassortment Demonstrates that the 1918 Influenza Virus Is Functionally Compatible with a Low-Pathogenicity Avian Influenza Virus in Mice

(2012) L. Qi et al.   JOURNAL OF VIROLOGY

Engineering H5N1 avian influenza viruses to study human adaptation

(2012) David M. Morens et al.   NATURE

The Potential of Avian H1N1 Influenza A Viruses to Replicate and Cause Disease in Mammalian Models

(2012) Zeynep A. Koçer et al.   PLoS One

Reconstruction of the 1918 Influenza Virus: Unexpected Rewards from the Past

(2012) J. K. Taubenberger et al.   mBio

Emergence of Mammalian Species-Infectious and -Pathogenic Avian Influenza H6N5 Virus with No Evidence of Adaptation

(2011) J.-H. Nam et al.   JOURNAL OF VIROLOGY

Reversion of PB2-627E to -627K during Replication of an H5N1 Clade 2.2 Virus in Mammalian Hosts Depends on the Origin of the Nucleoprotein

(2011) J. Bogs et al.   JOURNAL OF VIROLOGY

Autopsy series of 68 cases dying before and during the 1918 influenza pandemic peak

(2011) Z.-M. Sheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pandemic influenza: certain uncertainties

(2011) David M. Morens et al.   REVIEWS IN MEDICAL VIROLOGY

The ability of pandemic influenza virus hemagglutinins to induce lower respiratory pathology is associated with decreased surfactant protein D binding

(2011) Li Qi et al.   VIROLOGY

Insights on influenza pathogenesis from the grave

(2011) Jeffery K. Taubenberger et al.   VIRUS RESEARCH

Influenza Virus Evolution, Host Adaptation, and Pandemic Formation

(2010) Jeffery K. Taubenberger et al.   Cell Host & Microbe

Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig models

(2010) Wenjun Ma et al.   VIROLOGY

Full genome comparison and characterization of avian H10 viruses with different pathogenicity in Mink (Mustela vison) reveals genetic and functional differences in the non-structural gene

(2010) Siamak Zohari et al.   Virology Journal

A Single-Amino-Acid Substitution in a Polymerase Protein of an H5N1 Influenza Virus Is Associated with Systemic Infection and Impaired T-Cell Activation in Mice

(2009) J. L. Fornek et al.   JOURNAL OF VIROLOGY

Different Evolutionary Trajectories of European Avian-Like and Classical Swine H1N1 Influenza A Viruses

(2009) E. J. Dunham et al.   JOURNAL OF VIROLOGY

An early ‘classical’ swine H1N1 influenza virus shows similar pathogenicity to the 1918 pandemic virus in ferrets and mice

(2009) Matthew J. Memoli et al.   VIROLOGY

The Pathology of Influenza Virus Infections

(2008) Jeffery K. Taubenberger et al.   Annual Review of Pathology-Mechanisms of Disease

Avian Influenza H6 Viruses Productively Infect and Cause Illness in Mice and Ferrets

(2008) L. Gillim-Ross et al.   JOURNAL OF VIROLOGY

Cross-Species Virus Transmission and the Emergence of New Epidemic Diseases

(2008) C. R. Parrish et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus

(2008) C. Pappas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Evolutionary Genetics and Emergence of Avian Influenza Viruses in Wild Birds

(2008) Vivien G. Dugan et al.   PLoS Pathogens

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens