H5N1 Influenza Virus Pathogenesis in Genetically Diverse Mice Is Mediated at the Level of Viral Load

The 2009 pandemic H1N1 influenza and indigenous populations of the Americas and the Pacific

(2017) G La Ruche et al.   Eurosurveillance

Induction of Proinflammatory Cytokines in Primary Human Macrophages by Influenza A Virus (H5N1) Is Selectively Regulated by IFN Regulatory Factor 3 and p38 MAPK

(2014) K. P. Y. Hui et al.   JOURNAL OF IMMUNOLOGY

Genetic analysis of complex traits in the emerging Collaborative Cross

(2011) David L. Aylor et al.   GENOME RESEARCH

Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation

(2011) Ross Vlahos et al.   PLoS Pathogens

What is the evidence of a role for host genetics in susceptibility to influenza A/H5N1?

(2010) P. HORBY et al.   EPIDEMIOLOGY AND INFECTION

Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

(2010) Andri Rauch et al.   GASTROENTEROLOGY

Human TRAF3 Adaptor Molecule Deficiency Leads to Impaired Toll-like Receptor 3 Response and Susceptibility to Herpes Simplex Encephalitis

(2010) Rebeca Pérez de Diego et al.   IMMUNITY

Lethal Dissemination of H5N1 Influenza Virus Is Associated with Dysregulation of Inflammation and Lipoxin Signaling in a Mouse Model of Infection

(2010) C. Cilloniz et al.   JOURNAL OF VIROLOGY

Cross-Reactive Neutralizing Antibodies Directed against Pandemic H1N1 2009 Virus Are Protective in a Highly Sensitive DBA/2 Mouse Influenza Model

(2010) A. C. M. Boon et al.   JOURNAL OF VIROLOGY

Genomic Profiling of Tumor Necrosis Factor Alpha (TNF- ) Receptor and Interleukin-1 Receptor Knockout Mice Reveals a Link between TNF-  Signaling and Increased Severity of 1918 Pandemic Influenza Virus Infection

(2010) S. E. Belisle et al.   JOURNAL OF VIROLOGY

A novel strategy for genetic dissection of complex traits: the population of specific chromosome substitution strains from laboratory and wild mice

(2010) Junhua Xiao et al.   MAMMALIAN GENOME

Influenza H5N1 and H1N1 Virus Replication and Innate Immune Responses in Bronchial Epithelial Cells Are Influenced by the State of Differentiation

(2010) Renee W. Y. Chan et al.   PLoS One

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

(2010)   SCIENCE

Correlation between polymerase activity and pathogenicity in two duck H5N1 influenza viruses suggests that the polymerase contributes to pathogenicity

(2010) Bo Wah Leung et al.   VIROLOGY

Viral Replication Rate Regulates Clinical Outcome and CD8 T Cell Responses during Highly Pathogenic H5N1 Influenza Virus Infection in Mice

(2010) Yasuko Hatta et al.   PLoS Pathogens

Human cancer cells have specifically lost the ability to induce the synergistic state caused by tumor necrosis factor plus interferon-β

(2009) Eric Bartee et al.   CYTOKINE

Viral Genetic Determinants of H5N1 Influenza Viruses That Contribute to Cytokine Dysregulation

(2009) Ka Pun Mok et al.   JOURNAL OF INFECTIOUS DISEASES

A Single-Amino-Acid Substitution in a Polymerase Protein of an H5N1 Influenza Virus Is Associated with Systemic Infection and Impaired T-Cell Activation in Mice

(2009) J. L. Fornek et al.   JOURNAL OF VIROLOGY

Host Genetic Variation Affects Resistance to Infection with a Highly Pathogenic H5N1 Influenza A Virus in Mice

(2009) A. C. M. Boon et al.   JOURNAL OF VIROLOGY

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

(2009) David L. Thomas et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

(2009) C. R. Baskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational Genetic Mapping in Mice: The Ship Has Sailed

(2009) M. Zheng et al.   Science Translational Medicine

Lethal Influenza Virus Infection in Macaques Is Associated with Early Dysregulation of Inflammatory Related Genes

(2009) Cristian Cillóniz et al.   PLoS Pathogens

Hyperinduction of Cyclooxygenase‐2–Mediated Proinflammatory Cascade: A Mechanism for the Pathogenesis of Avian Influenza H5N1 Infection

(2008) Suki M. Y. Lee et al.   JOURNAL OF INFECTIOUS DISEASES

The Addition of Tumor Necrosis Factor plus Beta Interferon Induces a Novel Synergistic Antiviral State against Poxviruses in Primary Human Fibroblasts

(2008) E. Bartee et al.   JOURNAL OF VIROLOGY

The Collaborative Cross, developing a resource for mammalian systems genetics: A status report of the Wellcome Trust cohort

(2008) Fuad A. Iraqi et al.   MAMMALIAN GENOME

Genetic Compatibility and Virulence of Reassortants Derived from Contemporary Avian H5N1 and Human H3N2 Influenza A Viruses

(2008) Li-Mei Chen et al.   PLoS Pathogens

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens