Phenazine N,N′-dioxide scaffold as selective hypoxic cytotoxin pharmacophore. Structural modifications looking for further DNA topoisomerase II-inhibition activity
出版年份 2013 全文链接
标题
Phenazine N,N′-dioxide scaffold as selective hypoxic cytotoxin pharmacophore. Structural modifications looking for further DNA topoisomerase II-inhibition activity
作者
关键词
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出版物
MedChemComm
Volume 4, Issue 3, Pages 595
出版商
Royal Society of Chemistry (RSC)
发表日期
2013-01-30
DOI
10.1039/c3md00022b
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- (2012) Christian Bailly CHEMICAL REVIEWS
- High DNA Affinity of a Series of Peptide Linked Diaromatic Guanidinium-like Derivatives
- (2012) Padraic S. Nagle et al. JOURNAL OF MEDICINAL CHEMISTRY
- 2D- and 3D-Quantitative Structure-Activity Relationship Studies for a Series of Phenazine N,N’-Dioxide as Antitumour Agents
- (2011) Jonathan Da Cunha et al. Chemical Biology & Drug Design
- Study of benzo[a]phenazine 7,12-dioxide as selective hypoxic cytotoxin-scaffold. Identification of aerobic-antitumoral activity through DNA fragmentation
- (2010) María Laura Lavaggi et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Benzoquinazoline derivatives as new agents affecting DNA processing
- (2010) Giovanni Marzaro et al. BIOORGANIC & MEDICINAL CHEMISTRY
- DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs
- (2010) Yves Pommier et al. CHEMISTRY & BIOLOGY
- Structural modifications on the phenazine N,N′-dioxide-scaffold looking for new selective hypoxic cytotoxins
- (2010) María Laura Lavaggi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Lethal and mutagenic interactions between γ-rays, cisplatin and etoposide at the cellular and molecular levels
- (2010) Olga Lillo et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- The Hypoxia-Activated ProDrug AQ4N Penetrates Deeply in Tumor Tissues and Complements the Limited Distribution of Mitoxantrone
- (2009) O. Tredan et al. CANCER RESEARCH
- Role of hypoxia in the hallmarks of human cancer
- (2009) Kai Ruan et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Asymmetrical Diaromatic Guanidinium/2-Aminoimidazolinium Derivatives: Synthesis and DNA Affinity
- (2009) Padraic S. Nagle et al. JOURNAL OF MEDICINAL CHEMISTRY
- Live Cell Cytotoxicity Studies: Documentation of the Interactions of Antitumor Active Dirhodium Compounds with Nuclear DNA
- (2009) J. Dafhne Aguirre et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Multiplex binding modes of toluidine blue with calf thymus DNA and conformational transition of DNA revealed by spectroscopic studies
- (2009) Juan Wang et al. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
- Antitumoral Effect of PhenazineN5,N10-Dioxide Derivatives on Caco-2 Cells
- (2008) Olga Gisela Pachón et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Differential Enzymatic Reductions Governing the Differential Hypoxia-Selective Cytotoxicities of Phenazine 5,10-Dioxides
- (2008) María Laura Lavaggi et al. CHEMICAL RESEARCH IN TOXICOLOGY
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