期刊
MEDCHEMCOMM
卷 3, 期 7, 页码 784-787出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2md20049j
关键词
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资金
- University of Saarland
- Interreg IVA Programme (Corena-Network) [35GR11051]
Traditionally, the activity of organochalcogen based redox catalysts in cancer cells has been associated with the increase of ROS levels. Using a phenotype guided approach we were able to identify tubulin and actin as targets of tellurium containing redox catalysts. This is the first detection of a defined intracellular target of such compounds.
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