标题
Molecular obesity, potency and other addictions in drug discovery
作者
关键词
-
出版物
MedChemComm
Volume 2, Issue 5, Pages 349
出版商
Royal Society of Chemistry (RSC)
发表日期
2011-03-07
DOI
10.1039/c1md00017a
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Probing the links between in vitro potency, ADMET and physicochemical parameters
- (2011) M. Paul Gleeson et al. NATURE REVIEWS DRUG DISCOVERY
- Thermodynamics guided lead discovery and optimization
- (2010) György G. Ferenczy et al. DRUG DISCOVERY TODAY
- Getting physical in drug discovery: a contemporary perspective on solubility and hydrophobicity
- (2010) Alan P. Hill et al. DRUG DISCOVERY TODAY
- Lipophilicity in drug discovery
- (2010) Michael J Waring Expert Opinion on Drug Discovery
- Enthalpic Efficiency of Ligand Binding
- (2010) György G. Ferenczy et al. Journal of Chemical Information and Modeling
- An Analysis of the Binding Efficiencies of Drugs and Their Leads in Successful Drug Discovery Programs
- (2010) Emanuele Perola JOURNAL OF MEDICINAL CHEMISTRY
- Defining optimum lipophilicity and molecular weight ranges for drug candidates—Molecular weight dependent lower logD limits based on permeability
- (2009) Michael J. Waring BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?
- (2009) Timothy J. Ritchie et al. DRUG DISCOVERY TODAY
- Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
- (2009) Frank Lovering et al. JOURNAL OF MEDICINAL CHEMISTRY
- 970 Million Druglike Small Molecules for Virtual Screening in the Chemical Universe Database GDB-13
- (2009) Lorenz C. Blum et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The influence of lead discovery strategies on the properties of drug candidates
- (2009) György M. Keserü et al. NATURE REVIEWS DRUG DISCOVERY
- Highly potent and selective chiral inhibitors of PDE5: An illustration of Pfeiffer’s rule
- (2008) Mark E. Bunnage et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Physiochemical drug properties associated with in vivo toxicological outcomes
- (2008) Jason D. Hughes et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Generation of a Set of Simple, Interpretable ADMET Rules of Thumb
- (2008) M. Paul Gleeson JOURNAL OF MEDICINAL CHEMISTRY
- The Thermodynamics of Protein–Ligand Interaction and Solvation: Insights for Ligand Design
- (2008) Tjelvar S.G. Olsson et al. JOURNAL OF MOLECULAR BIOLOGY
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