期刊
MEDCHEMCOMM
卷 2, 期 5, 页码 430-435出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1md00022e
关键词
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资金
- CNRS
- Ministere de l'Enseignement Superieur
- Ministere de la Defense
Novel ester prodrugs of ciprofloxacin were synthesized, and tested for their antimalarial and antitoxoplasma activity. These new compounds proved to be extremely efficient against these parasites. Molecular modeling and computational calculations were used to understand the mechanisms of action of these drugs.
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