Article
Urban Studies
Mahsa Najarsadeghi, Ehsan Dorostkar
Summary: This study examines the impact of virtual mobility on human mobility in Tehran's nightlife conditions, using Foursquare social media data. The research highlights the effects of Foursquare on nightlife and spatial interactions, emphasizing the importance of virtual mobility in shaping human behavior.
Review
Geriatrics & Gerontology
Paulo R. Carvalho do Nascimento, Martin Bilodeau, Stephane Poitras
Summary: The study investigated the impact of different definitions and measurement tools on the prevalence estimates of sarcopenia. Various operational definitions and tools were found, leading to a range of prevalence estimates. Establishing a unique definition, using accurate evaluation methods for muscle mass, and standardizing measurement tools are crucial for proper diagnosis and comparison of sarcopenia prevalence.
Article
Green & Sustainable Science & Technology
Ankita Das, Jan Konietzko, Nancy Bocken
Summary: The study found that most companies do not forecast the future environmental impacts of their business models when transitioning towards a circular economy. The most popular measurement method is rules of thumb, but lack of data, increased uncertainty during experimentation, and lack of knowledge are common barriers.
SUSTAINABLE PRODUCTION AND CONSUMPTION
(2022)
Article
Business
Diptiman Banerji, Aishwarya Ramasundaram, S. Sreejesh, Yupal S. S. Shukla, Ravi Chatterjee
Summary: Measuring the intangibility of services has been a concern for researchers. This study proposes the use of a discrete choice experiment (DCE) as a more accurate and generalizable method for measuring intangibility. The DCE method provides managers with a better way to measure and manage intangibility or similar service constructs, leading to improved customer satisfaction.
INTERNATIONAL JOURNAL OF CONSUMER STUDIES
(2023)
Article
Agriculture, Multidisciplinary
Sara Shostak
Summary: This paper critically analyzes program evaluation in contemporary urban agriculture, discussing practitioners' critiques of existing practices and their visions for alternative storytelling. It also explores their interest in policy advocacy, collective work for transformative social change, and establishing new relationships with funders.
AGRICULTURE AND HUMAN VALUES
(2022)
Review
Biochemistry & Molecular Biology
Jose Luis Araus, Shawn Carlisle Kefauver, Omar Vergara Diaz, Adrian Gracia-Romero, Fatima Zahra Rezzouk, Joel Segarra, Maria Luisa Buchaillot, Melissa Chang-Espino, Thomas Vatter, Rut Sanchez-Bragado, Jose Armando Fernandez Gallego, Maria Dolores Serret, Jordi Bort
Summary: High-throughput crop phenotyping plays a key role in crop genetic improvement. Remote sensing methods, combined with data processing and machine learning techniques, have widespread applications in phenotyping. This review also discusses the development of other lab-based tools and root phenotyping, as well as the use of aerial platforms and data processing technologies.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2022)
Article
Business, Finance
Thuy Duong Dang, Fabian Hollstein, Marcel Prokopczuk
Summary: Investors in corporate bonds tend to use the simple Sharpe ratio and Morningstar ratings instead of bond factor models. However, the easy manipulation of the Sharpe ratio and Morningstar ratings in bond markets can have potentially severe implications for market participants.
JOURNAL OF BANKING & FINANCE
(2022)
Review
Social Sciences, Interdisciplinary
Federica Cavazzoni, Alec Fiorini, Guido Veronese
Summary: The concept of agency is well recognized among social scientists, but there is still little agreement on its understanding and definition. Lack of consensus and standardized methodology for assessing agency is evident. Various instruments are currently adopted or developed to assess agency across different social contexts for adults, children, and youth.
SOCIAL INDICATORS RESEARCH
(2022)
Review
Ecology
Samuel R. P. -J. Ross, Owen L. Petchey, Takehiro Sasaki, David W. Armitage
Summary: The insurance effect of biodiversity, which refers to the stabilizing role of diversity in ecosystem properties, is supported by the variation in organismal responses to the environment. This variation, known as response diversity, is a crucial factor in ecological stability. This review article presents a methodological framework for quantifying response diversity from experimental and/or observational data, allowing for practical application in various settings. By capturing subtle variations in environmental responses and considering environment dependencies, this approach provides a new perspective for testing the relationship between diversity and stability and can be used for mapping, monitoring, and conserving biodiversity.
METHODS IN ECOLOGY AND EVOLUTION
(2023)
Article
Psychology, Multidisciplinary
Antonio Luis Moreno-Albarracin, Cristina Ortega-Rodriguez, Jose Carlos Alvarez-Lopez, Pedro Nunez-Cacho
Summary: One of the major challenges facing NPOs is to demonstrate proper use of resources, with transparency and good governance being key to building trust with stakeholders. Management indicators are essential for validating efficient and excellent decision-making, crucial for gaining social credibility.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Clinical Neurology
Nicolas von Ellenrieder, Hui Ming Khoo, Francois Dubeau, Jean Gotman
Summary: The sensitivity of intracerebral electrodes is related to electrode type and extent of generators, while not affected by contact size or distance. Numerical simulation is a useful tool for designing intracerebral electrodes and enhancing measurement interpretation.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Oncology
Karolina Lisy, Lena Ly, Helana Kelly, Melanie Clode, Michael Jefford
Summary: The study aimed to determine important quality criteria for optimal cancer survivorship care through an online modified reactive Delphi survey with experts including consumers, clinicians, researchers, policymakers, and quality and accreditation professionals. Criteria were ranked in three domains and the top 30 items formed the Quality Framework, focusing on policy support, survivorship program existence, appropriate processes for survivors' needs, and reporting outcomes.
Article
Public, Environmental & Occupational Health
Catherine E. Harnois
Summary: The Everyday Discrimination Scale is widely used in research to study the health effects of discrimination, but little is known about how respondents interpret and answer the questions in the scale. This study analyzed cognitive interview data and found significant variation in interpretation among respondents, with racial/ethnic and gender statuses influencing interpretation.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Chemistry, Physical
Peter Hamm
Summary: A new application of high-repetition rate, femtosecond Yb-laser/amplifier systems is introduced for transient 2D IR spectroscopy covering the time range from micro- to milliseconds. This approach combines the measurement of 2D IR spectra with the time separation from an actinic pump pulse, utilizing the high repetition rate of these lasers systems to offer high time resolution and enable the measurement of multiple 2D IR spectra. The well-studied photocycle of bacteriorhodopsin is used as a demonstration object in this proof-of-principle experiment.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Article
Neurosciences
C. Nathan Vannatta, Taylor Blackman, Thomas W. Kernozek
Summary: Comparing the performance of one leg to another is a common means of assessing running gait, but limited data exists regarding the amount of asymmetry that may be expected during running. This study aimed to describe asymmetry in collegiate cross-country runners and compare different methods of calculating asymmetry.
Article
Biochemistry & Molecular Biology
Silke Kerruth, Catherine Coates, Celine D. Duerst, Thomas G. Oertner, Katalin Torok
JOURNAL OF BIOLOGICAL CHEMISTRY
(2019)
Meeting Abstract
Biophysics
Gert Rapp, Christian Schulze, Thomas Oertner, Florian Huhn
BIOPHYSICAL JOURNAL
(2019)
Article
Multidisciplinary Sciences
Alberto Perez-Alvarez, Brenna C. Fearey, Ryan J. O'Toole, Wei Yang, Ignacio Arganda-Carreras, Paul J. Lamothe-Molina, Benjamien Moeyaert, Manuel A. Mohr, Lauren C. Panzera, Christian Schulze, Eric R. Schreiter, J. Simon Wiegert, Christine E. Gee, Michael B. Hoppa, Thomas G. Oertner
NATURE COMMUNICATIONS
(2020)
Article
Multidisciplinary Sciences
Alberto Perez-Alvarez, Shuting Yin, Christian Schulze, John A. Hammer, Wolfgang Wagner, Thomas G. Oertner
NATURE COMMUNICATIONS
(2020)
Article
Immunology
Laura Laprell, Christian Schulze, Marie-Luise Brehme, Thomas G. Oertner
Summary: Microglia respond to danger signals by extending cellular processes towards the signal source, with optogenetic depolarization slowing down their chemotactic response. This is mimicked by reducing extracellular Ca2+ concentration, suggesting hyperpolarization is crucial for rapid stimulus-response coupling in microglia. Unlike typical excitable cells, the activating response in microglia is inhibited by depolarizing channelrhodopsins.
JOURNAL OF NEUROINFLAMMATION
(2021)
Correction
Immunology
Laura Laprell, Christian Schulze, Marie-Luise Brehme, Thomas G. Oertner
JOURNAL OF NEUROINFLAMMATION
(2021)
Editorial Material
Neurosciences
Christine E. Gee, Thomas G. Oertner
Summary: The article introduces a new tool paCaMKII, which can induce long-term potentiation of hippocampal synapses through light activation, expanding the toolkit for modifying brain connectivity at the synaptic level.
TRENDS IN NEUROSCIENCES
(2021)
Article
Neurosciences
Alberto Perez-Alvarez, Florian Huhn, Celine D. Durst, Andreas Franzelin, Paul J. Lamothe-Molina, Thomas G. Oertner
Summary: The introduction of TubuTag allows researchers to investigate calcium signaling in dendrites by integrating cytoplasmic calcium signals through irreversible photoconversion from green to red fluorescence. Using a custom two-photon microscope, they were able to observe pyramidal neurons in CA1 at subcellular resolution, revealing a gradient in the amplitude of dendritic calcium signals in the most distal parts of the apical dendrite. This tool will facilitate the study of dendritic signal integration and calcium homeostasis in large populations of neurons by allowing the read-out of fluorescence several hours after photoconversion.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2021)
Article
Biology
Shang Yang, Oana M. Constantin, Divya Sachidanandan, Hannes Hofmann, Tobias C. Kunz, Vera Kozjak-Pavlovic, Thomas G. Oertner, Georg Nagel, Robert J. Kittel, Christine E. Gee, Shiqiang Gao
Summary: The study engineered a membrane-anchored photoactivatable adenylyl cyclase that rapidly increases cAMP levels in response to light without accumulating cAMP in the dark. This optogenetic tool, PACmn, allows precise and transient stimulation of cAMP signaling pathways in diverse cell types, making it valuable for research in cell-autonomous signaling mechanisms.
Article
Biochemical Research Methods
Mauro Pulin, Kilian E. Stockhausen, Olivia A. Masseck, Martin Kubitschke, Bjoern Busse, J. Simon Wiegert, Thomas G. Oertner
Summary: It is found that there is strong polarization sensitivity in GPCR-based neurotransmitter sensors, which leads to the loss of membrane signal in dendrites parallel to the polarization direction of the excitation beam. By designing an optical device that generates interleaved pulse trains of orthogonal polarization, the directional bias in fluorescence and second-harmonic (SHG) images can be eliminated.
BIOMEDICAL OPTICS EXPRESS
(2022)
Article
Neurosciences
Margarita Anisimova, Bas van Bommel, Rui Wang, Marina Mikhaylova, Joern Simon Wiegert, Thomas G. Oertner, Christine E. Gee
Summary: The study uses optogenetic stimulation to induce STDP and observes timing-dependent depression and potentiation. This study does not require electrodes and results suggest that synaptic depression after anticausal activation is a transient phenomenon.
Article
Multidisciplinary Sciences
Brenna C. Fearey, Lars Binkle, Daniel Mensching, Christian Schulze, Christian Lohr, Manuel A. Friese, Thomas G. Oertner, Christine E. Gee
Summary: The TRPM4 channel has been found to play a significant role in disease severity in multiple sclerosis and neuronal cell death in brain injury. It was discovered that TRPM4 does not significantly affect basal hippocampal synaptic transmission but does contribute to excitatory postsynaptic responses in the acute phase of EAE in a glibenclamide-sensitive manner.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Tim Fieblinger, Alberto Perez-Alvarez, Paul J. Lamothe-Molina, Christine E. Gee, Thomas G. Oertner
Summary: This study reveals the regulation of striatal excitatory neurons by phosphodiesterase PDE1 and cGMP, showing that blocking PDE1 activity can increase synaptic transmission and affect motor skill learning in mice.
Article
Multidisciplinary Sciences
Celine D. Duerst, J. Simon Wiegert, Christian Schulze, Nordine Helassa, Katalin Toeroek, Thomas G. Oertner
Summary: In this study, the researchers used a genetically encoded glutamate sensor to optically measure evoked transmitter release at Schaffer collateral synapses. They found that the vesicular release probability of individual synapses is highly correlated with their potency, while the number of releasable vesicles only affects synaptic output under specific conditions.
NATURE COMMUNICATIONS
(2022)
Article
Multidisciplinary Sciences
Paul J. Lamothe-Molina, Andreas Franzelin, Lennart Beck, Dong Li, Lea Auksutat, Tim Fieblinger, Laura Laprell, Joachim Alhbeck, Christine E. Gee, Matthias Kneussel, Andreas K. Engel, Claus C. Hilgetag, Fabio Morellini, Thomas G. Oertner
Summary: Research shows that cFos expression patterns in the mouse dentate gyrus change dramatically from day to day, suggesting that this clock-like selection mechanism may aid in encoding episodic memories.
NATURE COMMUNICATIONS
(2022)
