Article
Surgery
Hira Shafeeq, Jody C. DiGiacomo, Kelley A. Sookraj, Noam Gerber, Alaa Bahr, Om N. Talreja, Swapna Munnangi, Sarah Cardozo-Stolberg, L. D. George Angus
Summary: The study demonstrates that implementing a multimodal pain management approach with IV APAP as the first-line therapy in older polytrauma patients can significantly reduce opioid use and is associated with a shorter hospital stay.
JOURNAL OF SURGICAL RESEARCH
(2022)
Review
Medicine, General & Internal
Aparna Chunduri, Amit Kumar Aggarwal
Summary: Multimodal analgesia has become a preferred method in orthopedic pain management, reducing early postoperative opioid usage and decreasing dependence on opioids.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Orthopedics
Qiuru Wang, Wanli Zhang, Tingting Xiao, Liying Wang, Ting Ma, Pengde Kang
Summary: This study evaluated the efficacy of preemptive opioids for pain management in patients who underwent total knee arthroplasty (TKA). The results showed that preemptive opioid administration did not provide clinical benefits over placebo. Orthopaedic surgeons should consider not using pre-operative opioids in patients undergoing TKA.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Jeffrey D. Swenson, Kevin M. Conrad, Nathan L. Pace, Kathleen Phillips, Charles L. Saltzman
Summary: The study investigated the use of a novel system for simultaneous dosing of nonopioid analgesics after ACL reconstruction surgery, and found that it significantly reduced pain and opioid use.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2022)
Article
Otorhinolaryngology
Joann M. Butkus, Samiat Awosanya, Elizabeth Reilly Scott, Natalie Perlov, Paavali Hannikainen, Sruti Tekumalla, Maria Armache, Matthew Stewart, Thomas Willcox, Rebecca Chiffer
Summary: This study aimed to validate alternative pain management strategies that can reduce reliance on opioids for postoperative pain management in otology. The study randomized adult patients who underwent outpatient otologic surgery into two treatment groups. The results showed that the addition of patient education, acetaminophen, and naproxen to postoperative opioid prescriptions significantly reduced opioid consumption without affecting pain scores or complication rates.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Plant Sciences
Amanda de Oliveira Marinho, Jessica de Santana Brito, Jainaldo Alves Da Costa, Abdenego Rodrigues Da Silva, Suellen Pedrosa Da Silva, Luciclaudio Cassimiro De Amorim, Maria Tereza dos Santos Correia, Patricia Maria Guedes Paiva, Alisson Macario De Oliveira, Leydianne Leite de Siqueira Patriota, Thiago Henrique Napolea
Summary: The study evaluated the antinociceptive activity of S. terebinthifolia leaf lectin (SteLL) and found that it has both peripheral and central analgesic effects, which are mediated through modulation of opioid receptors without affecting motor coordination in animals.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Review
Otorhinolaryngology
Beatrice C. Go, Cammille C. Go, Kevin Chorath, Alvaro Moreira, Karthik Rajasekaran
Summary: The study aimed to analyze the safety and efficacy of using multimodal analgesia in patients undergoing head and neck cancer surgery with free flap reconstruction. The results showed a significant decrease in postoperative opioid usage in the MMA groups, significant pain improvement, with no significant differences in surgical outcomes, complications, and adverse effects.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2022)
Article
Medicine, General & Internal
Terence Ong, Chiann Ni Thiam
Summary: Pain is a common issue among older people, but it is often underestimated and not properly treated. A comprehensive assessment is necessary to identify the cause, severity, impact, and treatment response of pain. Managing pain in older individuals requires a different approach due to frailty, multimorbidity, polypharmacy, sensory deficits, and cognitive impairment. This review provides a summary of a comprehensive approach to pain management in older people.
Article
Psychology, Biological
Michael M. Morgan, Tammy N. Hilgendorf, Ram Kandasamy
Summary: This study investigated the effects of fentanyl on hindpaw inflammation, administration, and withdrawal in rats. The results showed that the effects of fentanyl on activity levels varied depending on the dose and pain condition, and withdrawal from fentanyl resulted in opioid withdrawal symptoms.
PHYSIOLOGY & BEHAVIOR
(2023)
Article
Veterinary Sciences
Daphna Emanuel, Sabine B. R. Kaestner, Julien Delarocque, Anne J. Grob, Astrid Bienert-Zeit
Summary: The aim of this study was to compare the effects of butorphanol, buprenorphine, and levomethadone on sedation quality and postoperative analgesia in horses undergoing cheek tooth extraction. The results showed that levomethadone and buprenorphine had better analgesic effects, with buprenorphine also increasing locomotor activity. However, it is important to note that serum cortisol levels may be influenced by other factors.
VETERINARY SCIENCES
(2022)
Article
Chemistry, Medicinal
Ye Zhang, Bin He, Jinqiu Zhao, Muzi Zhang, Qinsong Ren, Wei Zhang, Shuai Xu, Zhengxue Quan, Yunsheng Ou
Summary: The study demonstrates that combination analgesia with celebrex, pregabalin, and ropivacaine is effective in alleviating pain after posterior spinal surgery, with reduced consumption of PCA compared to controls.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2021)
Article
Substance Abuse
Fares Qeadan, Erin Fanning Madden
Summary: The study found that receiving a naloxone prescription was associated with an increased risk of subsequent opioid overdose among patients with acute and chronic pain, suggesting that prescribers often identify patients most in need of naloxone.
Review
Oncology
Morena Shkodra, Augusto Caraceni
Summary: This review discusses treatment approaches for neuropathic cancer pain caused by nerve damage due to the tumor. Diagnosing and treating neuropathic cancer pain remains difficult and evidence for the best treatments is limited. This review summarizes current management options and provides insights on new promising treatments for neuropathic cancer pain.
Review
Pharmacology & Pharmacy
Mustafa Ayan, Orhan Ozsoy, Sedat Ozbay, Canan Akman, Neslihan Ergun Suzer, Ozgur Karcioglu
Summary: Pain is an unpleasant sensory and emotional experience that can originate from any region of the body and can occur with or without tissue injury. In acute medicine, physicians use procedural sedation and analgesia (PSA) to perform invasive and painful procedures. The choice of analgesic and sedative drugs should be individualized based on the specific condition.
CURRENT PHARMACEUTICAL DESIGN
(2023)
Article
Emergency Medicine
Ezra S. Hornik, Henry C. Thode Jr, Adam J. Singer
Summary: There were no significant sex, ethnic, or racial disparities in administration or prescription of analgesics or opioids in ED adult patients with long-bone fractures between 2016 and 2019.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2023)
Letter
Anesthesiology
Naveen Eipe, John Penning, Fatemeh Yazdi, Ranjeeta Mallick, Lucy Turner, Mohammed Toseef Ansari
Article
Anesthesiology
Jennifer Cogan, Naveen Eipe, Grisell Vargas-Schaffer, Marie-France Ouimette, Sylvain Belisle
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
(2017)
Review
Surgery
Adele Sandra Budiansky, Michael P. Margarson, Naveen Eipe
SURGERY FOR OBESITY AND RELATED DISEASES
(2017)
Article
Anesthesiology
Akash Goel, Saam Azargive, Joel S. Weissman, Harsha Shanthanna, John G. Hanlon, Bana Samman, Mary Dominicis, Karim S. Ladha, Wiplove Lamba, Scott Duggan, Tania Di Renna, Philip Peng, Clinton Wong, Avinash Sinha, Naveen Eipe, David Martell, Howard Intrater, Peter MacDougall, Kwesi Kwofie, Mireille St-Jean, Saifee Rashiq, Kari Van Camp, David Flamer, Michael Satok-Wolman, Hance Clarke
BRITISH JOURNAL OF ANAESTHESIA
(2019)
Article
Pharmacology & Pharmacy
Imane Belcaid, Naveen Eipe
Article
Medicine, General & Internal
Amer Jarrar, Adele Budiansky, Naveen Eipe, Caolan Walsh, Nicole Kolozsvari, Amy Neville, Joseph Mamazza
Letter
Anesthesiology
I. Foo, N. Eipe, A. F. Smith
Letter
Anesthesiology
Naveen Eipe, John Penning
ANESTHESIA AND ANALGESIA
(2021)
Editorial Material
Anesthesiology
Kim Phan, Naveen Eipe, Philippe Phan
CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE
(2022)
Article
Anesthesiology
I. Foo, A. J. R. Macfarlane, D. Srivastava, A. Bhaskar, H. Barker, R. Knaggs, N. Eipe, A. F. Smith
Summary: The use of intravenous lidocaine in peri-operative pain management should be considered carefully due to its potential benefits and risks, especially for patients with comorbidities. Proper approval from hospital medication governance systems and informed consent from patients are crucial before utilizing this 'high-risk' medicine. Dosage recommendations and timing of administration in relation to other local anesthetic interventions should also be strictly followed.
Article
Pharmacology & Pharmacy
Kyle De Oliveira, Naveen Eipe
DRUGS-REAL WORLD OUTCOMES
(2020)
Letter
Anesthesiology
Sivendiran Mahalingam, Reva Ramlogan, Naveen Eipe, Susan Madden, John Penning
CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE
(2018)
Meeting Abstract
Surgery
R. Wu, A. Jarrar, N. Eipe, A. Neville, J. Yelle, J. Mamazza
Article
Anesthesiology
N. Eipe, S. Gupta, J. Penning
Meeting Abstract
Anesthesiology
Naveen Eipe, Robert Wu, Amer Jarrar, Amy Neville, J. D. Yelle, Joseph Mamazza
ANESTHESIA AND ANALGESIA
(2017)