期刊
JOURNAL OF CHEMICAL RESEARCH
卷 -, 期 12, 页码 722-725出版社
SCIENCE REVIEWS 2000 LTD
DOI: 10.3184/174751914X14175406270662
关键词
Xylariaceae sp; naphthalenone; isocoumarin; antifungal activity
资金
- NIH [U01 TW007404]
- KIST Institutional Program [2Z04210-14-124]
- German National Academy of Sciences Leopoldina
A new naphthalenone, (R)-4,6,8-trihydroxy-3,4-dihydro-1(2H)-naphthalenone and a new isocoumarin, 6,8-dihydroxy(3R)-(2-oxopropyl)-3,4-dihydroisocoumarin, together with eight related known compounds were isolated from the endolichenic fungal species, CR1546C from Costa Rican lichen Sticta fuliginosa (Lobariaceae). Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques and chemical methods. All of the isolated compounds exhibited moderate antifungal activity against the yeast Candida albicans.
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