Mechanistic insights into the triazolylidene-catalysed Stetter and benzoin reactions: role of the N-aryl substituent

Exploiting Acyl and Enol Azolium Intermediates via N-Hetero- cyclic Carbene-Catalyzed Reactions of α-Reducible Aldehydes

(2012) Harit U. Vora et al.   ADVANCED SYNTHESIS & CATALYSIS

Structures and Reactivities of O-Methylated Breslow Intermediates

(2012) Biplab Maji et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nucleophilic Reactivities of Deoxy Breslow Intermediates: How Does Aromaticity Affect the Catalytic Activities of N-Heterocyclic Carbenes?

(2012) Biplab Maji et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Umpolung by N-Heterocyclic Carbenes: Generation and Reactivity of the Elusive 2,2-Diamino Enols (Breslow Intermediates)

(2012) Albrecht Berkessel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Intermolecular Stetter Reactions of Enolizable Aldehydes with Nitrostyrenes: Computational Study Provides Insight into the Success of the Catalyst

(2012) Daniel A. DiRocco et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nucleophilic Addition of Enols and Enamines to α,β-Unsaturated Acyl Azoliums: Mechanistic Studies

(2012) Ramesh C. Samanta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

Highly Enantioselective Intermolecular Stetter Reaction of Simple Acrylates: Synthesis of α-Chiral γ-Ketoesters

(2012) Nathalie E. Wurz et al.   CHEMISTRY-A EUROPEAN JOURNAL

2,6-Dimethoxyphenyl-Substituted N-Heterocyclic Carbenes (NHCs): A Family of Highly Electron-Rich Organocatalysts

(2012) Michael Schedler et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Isolable Analogues of the Breslow Intermediate Derived from Chiral Triazolylidene Carbenes

(2012) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Proton Transfer Reactions of Triazol-3-ylidenes: Kinetic Acidities and Carbon Acid pKa Values for Twenty Triazolium Salts in Aqueous Solution

(2012) Richard S. Massey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxyanion Steering and CH−π Interactions as Key Elements in an N-Heterocyclic Carbene-Catalyzed [4 + 2] Cycloaddition

(2012) Scott E. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHCs in Asymmetric Organocatalysis: Recent Advances in Azolium Enolate Generation and Reactivity

(2012) Andrew Smith et al.   SYNTHESIS-STUTTGART

Extending NHC-Catalysis: Coupling Aldehydes with Unconventional Reaction Partners

(2011) Akkattu T. Biju et al.   ACCOUNTS OF CHEMICAL RESEARCH

N-Heterocyclic Carbenes: Organocatalysts with Moderate Nucleophilicity but Extraordinarily High Lewis Basicity

(2011) Biplab Maji et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Synthesis of α-Amino Acid Derivatives by an NHC-Catalyzed Intermolecular Stetter Reaction

(2011) Thierry Jousseaume et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

α,β-Unsaturated Acyl Azoliums from N-Heterocyclic Carbene Catalyzed Reactions: Observation and Mechanistic Investigation

(2011) Jessada Mahatthananchai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Asymmetric NHC-Catalyzed Hydroacylation of Unactivated Alkenes

(2011) Isabel Piel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral N-heterocyclic carbene catalyzed annulation of α,β-unsaturated aldehydes with 1,3-dicarbonyls

(2011) Zhi-Qiang Zhu et al.   CHEMICAL COMMUNICATIONS

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Mechanistic Insights on N-Heterocyclic Carbene-Catalyzed Annulations: The Role of Base-Assisted Proton Transfers

(2011) Pragya Verma et al.   JOURNAL OF ORGANIC CHEMISTRY

Quantum Mechanical Investigation of the Effect of Catalyst Fluorination in the Intermolecular Asymmetric Stetter Reaction

(2011) Joann M. Um et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene and Brønsted Acid Cooperative Catalysis: Asymmetric Synthesis oftrans-γ-Lactams

(2011) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Intermolecular Stetter Reaction of Enals with Nitroalkenes: Enhancement of Catalytic Efficiency through Bifunctional Additives

(2011) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organic base effects in NHC promoted O- to C-carboxyl transfer; chemoselectivity profiles, mechanistic studies and domino catalysis

(2011) Craig D. Campbell et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Switching Regioselectivity in Crossed Acyloin Condensations between Aromatic Aldehydes and Acetaldehyde by AlteringN-Heterocyclic Carbene Catalysts

(2011) Ming Yu Jin et al.   ORGANIC LETTERS

Mechanistic Investigation of the Enantioselective Intramolecular Stetter Reaction: Proton Transfer Is the First Irreversible Step

(2011) Jennifer L. Moore et al.   ORGANIC LETTERS

EnantioselectiveN-Heterocyclic Carbene-Catalyzed Michael Addition to α,β-Unsaturated Aldehydes by Redox Oxidation

(2011) Zi-Qiang Rong et al.   ORGANIC LETTERS

Catalytic enantioselective Steglich rearrangements using chiral N-heterocyclic carbenes

(2011) Craig D. Campbell et al.   TETRAHEDRON-ASYMMETRY

The effect of the N-mesityl group in NHC-catalyzed reactions

(2011) Jessada Mahatthananchai et al.   Chemical Science

N-Heterocyclic Carbene-Catalyzed Reaction of Alkynyl Aldehydes with 1,3-Keto Esters or 1,3-Diketones

(2010) Zhi-Qiang Zhu et al.   ADVANCED SYNTHESIS & CATALYSIS

Aldehyde Umpolung by N-Heterocyclic Carbenes: NMR Characterization of the Breslow Intermediate in its Keto Form, and a Spiro-Dioxolane as the Resting State of the Catalytic System

(2010) Albrecht Berkessel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NHC-Catalyzed Michael Addition to α,β-Unsaturated Aldehydes by Redox Activation

(2010) Suman De Sarkar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

α-Aroyloxyaldehydes: scope and limitations as alternatives to α-haloaldehydes for NHC-catalysed redox transformations

(2010) Kenneth B. Ling et al.   CHEMICAL COMMUNICATIONS

NHC-Mediated Chlorination of Unsymmetrical Ketenes: Catalysis and Asymmetry

(2010) James Douglas et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Highly Chemoselective Direct Crossed Aliphatic−Aromatic Acyloin Condensations with Triazolium-Derived Carbene Catalysts

(2010) Sarah E. O’Toole et al.   JOURNAL OF ORGANIC CHEMISTRY

Flexibility of N-Heterocyclic Carbene Ligands in Ruthenium Complexes Relevant to Olefin Metathesis and Their Impact in the First Coordination Sphere of the Metal

(2010) Francesco Ragone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

On new N-heterocyclic carbene derived alkylidene imidazolines

(2010) Christiane E. I. Knappke et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chiral relay in NHC-mediated asymmetric β-lactam synthesis II; asymmetry from NHCs derived from acyclic 1,2-diamines

(2010) Nicolas Duguet et al.   TETRAHEDRON-ASYMMETRY

Chiral relay in NHC-mediated asymmetric β-lactam synthesis I; substituent effects in NHCs derived from (1R,2R)-cyclohexane-1,2-diamine

(2010) Nicolas Duguet et al.   TETRAHEDRON-ASYMMETRY

N-Heterocyclic Carbene-Mediated Enantioselective Addition of Phenols to Unsymmetrical Alkylarylketenes

(2009) Carmen Concellón et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic amide formation with α′-hydroxyenones as acylating reagents

(2009) Pei-Chen Chiang et al.   CHEMICAL COMMUNICATIONS

Highly Enantioselective Benzoin Condensation Reactions Involving a Bifunctional Protic Pentafluorophenyl-Substituted Triazolium Precatalyst

(2009) Louise Baragwanath et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Catalyzed Generation of α,β-Unsaturated Acyl Imidazoliums: Synthesis of Dihydropyranones by their Reaction with Enolates

(2009) Sarah J. Ryan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The enantioselective benzoin condensation promoted by chiral triazolium precatalysts: stereochemical control via hydrogen bonding

(2009) Sarah E. O'Toole et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Unusual Mechanistic Course of Some NHC-Mediated Transesterifications

(2009) Luca Pignataro et al.   ORGANIC LETTERS

Impact of Solvent Polarity on N-Heterocyclic Carbene-Catalyzed β-Protonations of Homoenolate Equivalents

(2009) Brooks E. Maki et al.   ORGANIC LETTERS

From Mono-Triazolium Salt to Bis-Triazolium Salt: Improvement of the Asymmetric Intermolecular Benzoin Condensation

(2008) Yajun Ma et al.   ADVANCED SYNTHESIS & CATALYSIS

[4+2] Cycloaddition of Ketenes withN-Benzoyldiazenes Catalyzed by N-Heterocyclic Carbenes

(2008) Xue-Liang Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biomimetic Carbene-Catalyzed Oxidations of Aldehydes Using TEMPO

(2008) Joyram Guin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Mechanism of the Stetter Reaction - A DFT Study

(2008) Kirsty J. Hawkes et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Probing the Efficiency of N-Heterocyclic Carbene PromotedO- to C-Carboxyl Transfer of Oxazolyl Carbonates

(2008) Jennifer E. Thomson et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic carbene catalysed β-lactam synthesis

(2008) Nicolas Duguet et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of enantiopure triazolium salts from pyroglutamic acid and their evaluation in the benzoin condensation

(2008) Dieter Enders et al.   TETRAHEDRON-ASYMMETRY

Development of Chiral Bicyclic Triazolium Salt Organic Catalysts: The Importance of theN-Aryl Substituent

(2007) Tomislav Rovis   CHEMISTRY LETTERS