Article
Biochemistry & Molecular Biology
Shaun T. Mutter, Robert J. Deeth, Matthew Turner, James A. Platts
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2018)
Article
Chemistry, Inorganic & Nuclear
Darren M. C. Ould, Alex C. Rigby, Lewis C. Wilkins, Samuel J. Adams, James A. Platts, Simon J. A. Pope, Emma Richards, Rebecca L. Melen
Article
Crystallography
Jonathan J. Du, Felcia Lai, Linda Varadi, Peter A. Williams, Paul W. Groundwater, James A. Platts, David E. Hibbs, Jacob Overgaard
Article
Chemistry, Inorganic & Nuclear
Margot N. Wenzel, Andreia F. Mosca, Valentina Graziani, Brech Aikman, Sophie R. Thomas, Andreia de Almeida, James A. Platts, Nazzareno Re, Cecilia Coletti, Alessandro Marrone, Graca Soveral, Angela Casini
INORGANIC CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Matthew Turner, Shaun T. Mutter, James A. Platts
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2019)
Article
Chemistry, Inorganic & Nuclear
Nicholas Azzarelli, Shashikanth Ponnala, Alexander Aguirre, Sara J. Dampf, Margaret P. Davis, Michael T. Ruggiero, Valerie Lopez Diaz, John W. Babich, Michael Coogan, Timothy Korter, Robert P. Doyle, Jon Zubieta
INORGANICA CHIMICA ACTA
(2019)
Article
Biochemical Research Methods
Haralambos Tzoupis, Agathi Nteli, Jamie Platts, Efi Mantzourani, Theodore Tselios
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2019)
Article
Chemistry, Inorganic & Nuclear
Stephen L. J. Luckham, Andrea Folli, James A. Platts, Emma Richards, Damien M. Murphy
Article
Multidisciplinary Sciences
Matthew Turner, Shaun T. Mutter, Oliver D. Kennedy-Britten, James A. Platts
Article
Chemistry, Multidisciplinary
Katharina Mueller, Harald Foerstendorf, Robin Steudtner, Satoru Tsushima, Michael U. Kumke, Gregory Lefevre, Joerg Rothe, Harris Mason, Zoltan Szabo, Ping Yang, Christian K. R. Adam, Remi Andre, Katlen Brennenstuhl, Ion Chiorescu, Herman M. Cho, Gaelle Creff, Frederic Coppin, Kathy Dardenne, Christophe Den Auwer, Bjoern Drobot, Sascha Eidner, Nancy J. Hess, Peter Kaden, Alena Kremleva, Jerome Kretzschmar, Sven Krueger, James A. Platts, Petra J. Panak, Robert Polly, Brian A. Powell, Thomas Rabung, Roland Redon, Pascal E. Reiller, Notker Roesch, Andre Rossberg, Andreas C. Scheinost, Bernd Schimmelpfennig, Georg Schreckenbach, Andrej Skerencak-Frech, Vladimir Sladkov, Pier Lorenzo Solari, Zheming Wang, Nancy M. Washton, Xiaobin Zhang
Article
Chemistry, Inorganic & Nuclear
Barbora Mala, Laura E. Murtagh, Charlotte M. A. Farrow, Geoffrey R. Akien, Nathan R. Halcovich, Sarah L. Allinson, James A. Platts, Michael P. Coogan
Summary: This study reports the formation of dinuclear complexes from thiophenolate ligands, as well as the photochemical oxidation to sulfinates, leading to the discovery of tunable photophysics depending on the 1,2-diimine ligands. Different ligand conditions result in various types of complexes, with photooxidation yielding previously unreported Pt(IV)-SO2R complexes exhibiting multiple absorption characteristics.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Medicinal
Marta Redrado, Miriam Minana, Michael P. Coogan, M. Concepcion Gimeno, Vanesa Fernandez-Moreira
Summary: This study synthesized bioactive and luminescent cyclometallated iridium complexes with benzimidazole derivatives as auxiliary mimics of nucleotides. The complexes exhibited orange and green emission, with increased quantum yield under anaerobic conditions. The complexes also showed enhanced antiproliferative activity against lung cancer cells upon irradiation, making them potential candidates for photodynamic therapy.
Article
Chemistry, Physical
Lefteris Danos, Nathan R. Halcovitch, Ben Wood, Henry Banks, Michael P. Coogan, Nicholas Alderman, Liping Fang, Branislav Dzurnak, Tom Markvart
FARADAY DISCUSSIONS
(2020)
Article
Chemistry, Inorganic & Nuclear
Tamara Boltersdorf, Junaid Ansari, Elena Y. Senchenkova, Lijun Jiang, Andrew J. P. White, Michael Coogan, Felicity N. E. Gavins, Nicholas J. Long
DALTON TRANSACTIONS
(2019)
Article
Chemistry, Inorganic & Nuclear
Stefano Nuzzo, Jan van Leusen, Brendan Twamtey, James A. Platts, Paul Koegerter, Robert J. Baker
DALTON TRANSACTIONS
(2019)
Article
Chemistry, Multidisciplinary
Alexander M. Prophet, Kritanjan Polley, Gary J. Van Berkel, David T. Limmer, Kevin R. Wilson
Summary: The oxidation kinetics of iodide by ozone at the air-water interface is studied in single microdroplets. Molecular simulations and kinetic modeling are used to understand the underlying multiphase mechanism.
Article
Chemistry, Multidisciplinary
Rong Zhang, Jiajing Lan, Fei Wang, Shumei Chen, Jian Zhang
Summary: By utilizing 1,1'-ferrocene dicarboxylic acid as a chelating and surface protection ligand, we have synthesized multi-nuclear indium oxide clusters with varying nuclear sizes, including heptanuclear and thirteen-nuclear clusters. These clusters possess labile coordination sites, allowing for structural modification and self-assembly, resulting in the formation of various cluster structures.
Article
Chemistry, Multidisciplinary
Hui Wang, Hui Liu, Mingsen Wang, Jiaheng Hou, Yongjun Li, Yuancheng Wang, Yingjie Zhao
Summary: Two supramolecular complexes were prepared using CBs and M1, and their single-crystal structures were analyzed by SCXRD. The unexpected 1:2 self-assembly structure between M1 and CB[8] was discovered for the first time. These complexes exhibit unique photophysical properties and provide valuable information about the structure and photophysical properties of supramolecular complexes.
Article
Chemistry, Multidisciplinary
Chang-Hee Lee, Sookil Park, Sanggil Kim, Ji Young Hyun, Hyun Soo Lee, Injae Shin
Summary: The epidermal growth factor receptor (EGFR) is a cell-surface glycoprotein involved in cell proliferation and tumor development. This study used a fluorescently labeled EGFR to investigate its time-dependent endocytosis in live cells and found that appended glycans affect EGFR internalization. Additionally, the study detected sialic acid residues attached to EGFR on the live cell surface using FRET-based imaging. This research provides valuable insights into the cellular functions of EGFR.
Article
Chemistry, Multidisciplinary
Subhankar Sahu, Lokesh Kumar, Sumita Das, Dipti Gupta, Ruchi Anand
Summary: This study proposes a strategy that combines organic electronics with biosensor scaffolds to create a compact device for monitoring environmental aromatic pollution. By coupling biosensing protein MopR with an organic electrochemical transistor (OECT), a sensor module capable of efficient detection of phenol was designed. Exclusive phenol detection with minimal loss of sensitivity could be achieved in complex pollutant mixtures and real environmental samples.
Review
Chemistry, Multidisciplinary
Changseok Lee, Hyung-Joon Kang, Sungwoo Hong
Summary: The formation of C-N bonds through hydroamination reactions catalyzed by nickel hydrides has been a topic of recent interest. This approach offers a way to efficiently transform a variety of alkene and alkyne substrates into compounds enriched with C-N bonds. The review provides a concise overview of the underlying reaction mechanisms and aims to stimulate further progress in NiH-catalytic techniques and catalyst design.
Article
Chemistry, Multidisciplinary
Yueci Wu, Lu-Lu Sun, Hai-Hao Han, Xiao-Peng He, Weiguo Cao, Tony D. James
Summary: Drug-induced liver injury (DILI) is a common cause of acute liver failure in the USA and Europe, but most cases can be recovered or prevented by discontinuing the offending drug. Recent research has found that peroxynitrite (ONOO-) can be used as a potential indicator for early diagnosis of DILI, and there is an urgent need to establish a method to detect and track peroxynitrite in DILI cases. In this study, a FRET-based nano fluorescent probe CD-N-I was developed, which showed high selectivity and sensitivity in detecting peroxynitrite. The probe successfully detected exogenous peroxynitrite in live cells and endogenous peroxynitrite in APAP-induced liver injury of HepG2 cells.
Article
Chemistry, Multidisciplinary
Dmitry L. Lipilin, Mikhail O. Zubkov, Mikhail D. Kosobokov, Alexander D. Dilman
Summary: This article describes a direct photocatalytic method for the thiolation of unprotected acids, which was previously challenging. By using a thionocarbonate reagent with an N-O bond, the efficient conversion of carboxylic acids to thiols is achieved.
Article
Chemistry, Multidisciplinary
Jason Malenfant, Lucille Kuster, Yohann Gagne, Kouassi Signo, Maxime Denis, Sylvain Canesi, Mathieu Frenette
Summary: Raman microscopy can reveal compound-specific vibrational fingerprints without sample preparation. The combination of efficient theoretical calculations and a user-friendly software can accurately predict peak positions and provide match scores to assist with structure determination.
Article
Chemistry, Multidisciplinary
Jayoh A. Hernandez, Paul S. Micus, Sean Alec Lois Sunga, Luca Mazzei, Stefano Ciurli, Gabriele Meloni
Summary: Essential trace metals play crucial roles in the survival and virulence of bacterial pathogens. Helicobacter pylori requires nickel for colonization and persistence in the stomach, and NixA is an essential nickel transporter in this process. This study characterizes the selectivity and electrogenic nature of NixA-mediated nickel transport.
Article
Chemistry, Multidisciplinary
Tarali Devi, Kuheli Dutta, Jennifer Deutscher, Stefan Mebs, Uwe Kuhlmann, Michael Haumann, Beatrice Cula, Holger Dau, Peter Hildebrandt, Kallol Ray
Summary: This study emphasizes the importance of subtle electronic changes and secondary interactions in the stability of biologically relevant metal-dioxygen intermediates. It also shows that the role of the chloride ligand in stabilizing the Fe-III-(OOBu)-Bu-t moiety can extend to other anions, including the thiolate ligand.
Article
Chemistry, Multidisciplinary
Jacqueline R. Santhouse, Jeremy M. G. Leung, Lillian T. Chong, W. Seth Horne
Summary: By studying the folding kinetics and mechanism of the BdpA sequence, researchers found that altering the backbone connectivity can affect protein folding. This suggests that protein mimetic chains have a significant degree of plasticity in transitioning between unfolded and folded states.
Article
Chemistry, Multidisciplinary
Divanshu Gupta, Ralf Einholz, Holger F. Bettinger
Summary: This study presents the first direct spectroscopic evidence of a cyclic seven-membered iminoborane. Compared to linear amino-iminoboranes, this cyclic iminoborane exhibits weakened bond strength and lower Lewis acidity value. The study suggests that the reduced ring strain of cyclic iminoborane prevents nitrogen fixation but allows facile (2 + 2) cycloaddition reaction with C2H4.
Article
Chemistry, Multidisciplinary
Renny Mathew, Aniruddha Mazumder, Praveen Kumar, Julie Matula, Sharmarke Mohamed, Petr Brazda, Mahesh Hariharan, Brijith Thomas
Summary: This study reveals the packing arrangement of partially disordered nitro-perylenediimide (NO2-PDI) using a synergistic approach that combines 3D ED, ssNMR, and DFT techniques. By overcoming these challenges, this methodology opens up new avenues for material characterization, driving exciting advancements in the field.