A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells

Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer

(2013) Li-Jun Di et al.   Nature Communications

Targeting Tumour Proliferation with a Small-Molecule Inhibitor of AICAR Transformylase Homodimerization

(2012) Ian B. Spurr et al.   CHEMBIOCHEM

Protein–protein interaction inhibitors get into the groove

(2012) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

SIRT2 Maintains Genome Integrity and Suppresses Tumorigenesis through Regulating APC/C Activity

(2011) Hyun-Seok Kim et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The oligomeric state of CtBP determines its role as a transcriptional co-activator and co-repressor of Wingless targets

(2011) Chandan Bhambhani et al.   EMBO JOURNAL

AMPK: Evidence for an energy-sensing cytokinetic tumor suppressor

(2010) Alejandro Vazquez-Martin et al.   CELL CYCLE

A new layer of regulation is required to silence the DNA damage checkpoint

(2010) Yanchang Wang   CELL CYCLE

Therapeutic targeting of C-terminal binding protein in human cancer

(2010) Michael W. Straza et al.   CELL CYCLE

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

(2010) Daisuke Nakada et al.   NATURE

The engine driving the ship: metabolic steering of cell proliferation and death

(2010) Marisa R. Buchakjian et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CtBPs promote mitotic fidelity through their activities in the cell nucleus

(2010) C N Birts et al.   ONCOGENE

Interaction of ZEB and Histone Deacetylase with the PLDLS-binding cleft region of monomeric C-terminal Binding Protein 2

(2009) Ling-Jun Zhao et al.   BMC MOLECULAR BIOLOGY

The Transcriptional Corepressor CtBP: A Foe of Multiple Tumor Suppressors

(2009) G. Chinnadurai   CANCER RESEARCH

C-terminal binding protein maintains mitochondrial activities

(2009) J H Kim et al.   CELL DEATH AND DIFFERENTIATION

CtBPs Promote Cell Survival through the Maintenance of Mitotic Fidelity

(2009) L. M. Bergman et al.   MOLECULAR AND CELLULAR BIOLOGY

Direct inhibition of the NOTCH transcription factor complex

(2009) Raymond E. Moellering et al.   NATURE

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation

(2009) A. Almeida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Inhibition of HIV Budding by a Genetically Selected Cyclic Peptide Targeting the Gag−TSG101 Interaction

(2008) Ali Tavassoli et al.   ACS Chemical Biology

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

(2008) Rui-Hong Wang et al.   CANCER CELL

Roles of p53, Myc and HIF-1 in Regulating Glycolysis — the Seventh Hallmark of Cancer

(2008) S. J. Yeung et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inhibition of transcription factors with small organic molecules

(2008) Thorsten Berg   CURRENT OPINION IN CHEMICAL BIOLOGY