Article
Chemistry, Multidisciplinary
Marte Sofie Martinsen Holmsen, Charlie Blons, Abderrahmane Amgoune, Matthieu Regnacq, Denis Lesage, E. Daiann Sosa Carrizo, Pierre Lavedan, Yves Gimbert, Karinne Miqueu, Didier Bourissou
Summary: Gold(III) catalysis has developed rapidly in recent years, showing complementary features compared to gold(I) catalysis. However, little is known about the mechanism and key intermediates of Au(III)-catalyzed transformations. This study provides a detailed experimental/computational mechanistic study of the intermolecular hydroarylation of alkynes catalyzed by (P,C)-cyclometalated Au(III) complexes. The study identifies key intermediates and elucidates the reaction mechanism.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Jaime Martin, Enrique Gomez-Bengoa, Alexandre Genoux, Cristina Nevado
Summary: A catalytic method for synthesizing a variety of cyclometalated (C^N)gold(III) complexes is reported. The unprecedented Rh-to-Au(III) transmetalation allows for the easy transfer of (C^N) ligands between the two metals in a redox-neutral process. The reaction uses commercially available precursors and proceeds under mild and environmentally friendly conditions. Experimental and computational studies support a multi-step transmetalation mechanism from rhodium to gold as the underlying process for these transformations.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Inorganic & Nuclear
Miguel A. Soto, Veronica Carta, Maria T. Cano, Ryan J. Andrews, Brian O. Patrick, Mark J. MacLachlan
Summary: This study presents a compact cyclometalated platinum(II) complex that can respond to cationic guests, solvent molecules, and solvent polarity by producing changes in luminescence and color. This multiresponsive complex may have potential applications in sensors, hybrid supramolecular polymers, and metallogels.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Physical
Jessica Rodriguez, David Vesseur, Alexis Tabey, Sonia Mallet-Ladeira, Karinne Miqueu, Didier Bourissou
Summary: A (MeDalphos)AuCI complex has been discovered to efficiently catalyze the cross-coupling reaction of indoles and allyl acetates/alcohols. The reaction tolerates various functional groups and selectively produces branched C3-allylated products. It utilizes the hemilabile character of the P<^>N ligand.
Article
Chemistry, Multidisciplinary
Riccardo Bonsignore, Sophie R. Thomas, Mathilde Rigoulet, Christian Jandl, Alexander Poethig, Didier Bourissou, Giampaolo Barone, Angela Casini
Summary: The reactivity of gold complexes extends beyond pi-activation, showing promises for selective cross-couplings in various bond forming reactions. A gold-mediated C(sp(2))-C(sp) bond forming reaction was reported, and key intermediates were characterized using NMR, HR-ESI-MS, and crystallographic studies. DFT calculations provided insight into the structure and energetics, demonstrating rare examples of C(sp(2))-C(sp(2)) cross-couplings at Au(III).
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Lingkai Tang, Yafei Luo, Guangzhou Sun, Yu Jiang, Wenqin Luo, Xinru Yue, Zhigang Zhang, Chunran Zhang, Jianping Hu
Summary: The influence of graphene quantum dots (GQDs) as ligands on the emission properties and phosphorescence quantum yields of a series of Au(iii) complexes was investigated using density functional theory (DFT) and time-dependent density functional theory (TDDFT). The addition of GQDs as ligands was found to have little impact on the structural stability of the Au(iii) complexes. Interestingly, GQDs were found to enhance the phosphorescence quantum yield by suppressing the nonradiative leap and stabilizing the ground and excited states of the complexes.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Yann Le Gal, Agathe Filatre-Furcate, Dominique Lorcy, Olivier Jeannin, Thierry Roisnel, Vincent Dorcet, Diana Fontinha, Denise Francisco, Miguel Prudencio, Marta Martins, Catarina Soeiro, Silvia A. Sousa, Jorge H. Leitao, Tania S. Morais, Ines Bartolo, Nuno Taveira, Joana F. Guerreiro, Fernanda Marques
Summary: The biological properties of sixteen structurally related monoanionic gold (III) bis(dithiolene/diselenolene) complexes were evaluated. These complexes showed significant anticancer and antiplasmodial activities, as well as antibacterial/fungi activities. Some of the complexes exhibited strong interaction with human serum albumin. However, they did not show evident anti-HIV activity. The results highlight the potential clinical application of these complexes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Inorganic & Nuclear
Ming-Hin Chau, Aries Kwok-Heung Chan, Yikun Ren, Jia-Jun Jiang, Man-Kin Wong, Franco King -Chi Leung
Summary: Gold (III) complex-based amphiphiles in aqueous media have high structural sensitivity to external stimulations, which opens up new possibilities for soft functional material applications. In this study, a supramolecular assembly system of gold (III) amphiphiles controlled by counterions exchange is demonstrated. The luminescent properties of the gold (III) amphiphiles are enhanced by the introduction of σ-donating mono-alkynyl ligand. Furthermore, these gold (III) amphiphiles show good cytocompatibilities to human bone marrow-derived mesenchymal stem cells.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Chetan C. Chintawar, Vivek W. Bhoyare, Manoj V. Mane, Nitin T. Patil
Summary: The first report of enantioselective Au(I)/Au(III) redox catalysis using a newly designed hemilabile chiral (P,N)-ligand (ChetPhos) is presented. This concept has been demonstrated by the development of enantioselective 1,2-oxyarylation and 1,2-aminoarylation reactions, providing direct access to medicinally relevant compounds with high yields and enantioselectivities.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Aries Kwok-Heung Chan, Ming-Hin Chau, Yikun Ren, Jia-Jun Jiang, Man-Kin Wong, Franco King-Chi Leung
Summary: Gold (III) cyclometalated based amphiphiles in aqueous media exhibit excellent supramolecular transformations, providing new pathways for the fabrication of soft functional materials. A new chiral cyclometalated gold (III) amphiphile (GA) was reported, which forms lamellar nanostructures in aqueous media as confirmed by transmission electron microscopy (TEM). Counterion exchange with D-, L-, or racemic-camphorsulfonates enhances the supramolecular helicity of GA, leading to transformations from lamellar structure to vesicles and nanotubes with multiple equivalents of counterion. The limited cytotoxicity of GA in aqueous media demonstrates good biocompatibility.
Article
Engineering, Chemical
Jinsong Xia, Julia Twinney, Rajashekhar Marthi, Ahmad Ghahreman
Summary: In this paper, Fe3S4/Fe7S8 materials were used for the first time for Au(III) recovery, one of the materials exhibited ultra-high adsorption capacity (2020.7 mg/g). Various characterizations and adsorption tests confirmed its excellent properties, including high capacity and selectivity, good magnetism, low cost, and reusability. Characterization results revealed that Au(III) was recovered on the adsorbents through in-situ reduction, and the reduction mechanism was studied through intensive XRD and XPS analyses. This work introduced magnetic iron sulfide materials in Au(III) recovery and demonstrated their promising features.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Kun Sun, Yaoxuan Shi, Huiyi Li, Jingjing Shan, Chengyue Sun, Zhen-Yu Wu, Yujin Ji, Zhijiang Wang
Summary: The use of an Au-complex derived carbon nanotube-supported Au nanoclusters catalyst has been shown to enhance the performance of CO2 reduction, leading to the production of CO.
Article
Chemistry, Organic
Charles O. Oseghale, Dele Peter Fapojuwo, Oyekunle Azeez Alimi, Christianah Aarinola Akinnawo, Batsile M. Mogudi, Oluwatayo Racheal Onisuru, Reinout Meijboom
Summary: The developed eco-friendly alkali-promoted catalyst (Cs-Au/Co3O4) enables the oxidative dehydrogenative coupling of anilines to aromatic azo compounds without the need for base additives or molecular oxygen oxidants, using air as the oxidant. The catalyst shows reasonable reusability under milder reaction conditions, with enhanced catalytic activity attributed to increased basic site concentration, low reduction temperatures, and the effect of lattice oxygen on the nanomaterials. The higher basic strength of the cation-promoted catalyst leads to improved electron density of active Au species, resulting in higher yields of desired aromatic azo compounds.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Review
Biochemistry & Molecular Biology
Alexia Tialiou, Jiamin Chin, Bernhard K. Keppler, Michael R. Reithofer
Summary: This review summarizes the latest advances in NHCAu(I/III) complexes that interact with DNA and presents the latest research on acyclic diamino carbene gold complexes with anticancer activity, which offer additional design possibilities in targeted therapy.
Article
Metallurgy & Metallurgical Engineering
Yong Xiang, Yun Liu, Mingjie Li, Wencai Bai, Guoji Liu, Li Xu
Summary: A novel RFT-SA adsorbent with high adsorption capacity and selectivity, as well as easy collectability, has been developed for efficient gold recovery.
Article
Chemistry, Inorganic & Nuclear
Xiao-Han Yang, Min Li, Hui Peng, Qian Zhang, Shui-Xing Wu, Wan-Qing Xiao, Xing-Liang Chen, Zhi-Gang Niu, Guang-Ying Chen, Gao-Nan Li
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2019)
Article
Chemistry, Physical
Zhi-Wen Zhao, Qin-Qing Pan, Ying-Chen Duan, Yong Wu, Yun Geng, Shui-Xing Wu, Zhong-Min Su
JOURNAL OF PHYSICAL CHEMISTRY C
(2019)
Article
Chemistry, Physical
Xingman Liu, Min Zhang, Shuixing Wu, Ronglin Zhong, Yingying Liu, Ali Muhammad Arif, Yun Geng, Zhongmin Su
Article
Chemistry, Inorganic & Nuclear
Dongxu Gu, Weiting Yang, Guohua Ning, Fuxiang Wang, Shuixing Wu, Xiaodong Shi, Yinghui Wang, Qinhe Pan
INORGANIC CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Xingman Liu, Min Zhang, Ronglin Zhong, Shuixing Wu, Yingying Liu, Yun Geng, Zhongmin Su
CHEMISTRY-A EUROPEAN JOURNAL
(2020)
Article
Biochemical Research Methods
Yunpeng Bai, Yuqiang Liang, Guode Li, Shuixing Wu, Guangwen Wang, Yingbang Li, Yanling Liu, Chunbo Chen
Summary: The Maillard reaction is important in food, physiology, and traditional Chinese medicine, with primary products formed through Amadori rearrangement. Analysis of Amadori compounds' characteristic fragmentation and glycosidic bond configuration aids in their identification by mass spectrometry. Metal-ion-assisted analysis and quantum calculations provide insights into the fragmentation mechanisms and stability of metal complexes in Amadori compounds.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2021)
Article
Biochemical Research Methods
Yunpeng Bai, Hua Chen, Shuixing Wu, Guangwen Wang, Yingbang Li, Yanling Liu, Yisheng Huang
Summary: Under MALDI-FTICR MS conditions, Keggin-type silicopolyoxometalate anions can produce several series of singly charged molybdenum-containing/tungsten-containing ion clusters in negative-ion generating mode. The matrices have a significant influence on the formation of ion clusters, indicating the utility of MALDI method for obtaining novel ion clusters and showing the stability of these clusters.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Xingman Liu, Min Zhang, Yingtao Liu, Shuixing Wu, Zhongmin Su
Summary: In this study, a distinct Cr-Cr sextuple bond with an ultra-short length stabilized by equatorial alkali metals is reported. The bonding strength is enhanced due to the introduction of alkali metals, weakening the Cr-Cr 4s-4s effect.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Multidisciplinary
Yang Liu, Qing-qing Pan, Feng-wei Gao, Ying-chen Duan, Shui-xing Wu, Yu-he Kan, Zhong-min Su
Summary: By using DFT and TD-DFT methods, the relationship between structure and property of a series of homoleptic monocyclic and [2]catenanes gold(i) thiolates was analyzed. It was found that the [2]catenanes are more planar than the monocyclic molecules due to increased Au-S-Au bond angles in Au11 and Au12. The smaller Au-MIDLINE HORIZONTAL ELLIPSISAu contacts enhance the geometrical stability of the structures. The HOMO levels of the [2]catenanes are higher than those of the monocyclic molecules, and their absorption spectra exhibit a redshift consistent with the higher HOMO energy levels.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Physical
Hai-Ping Zhou, Shui-Xing Wu, Ying-Chen Duan, Feng-Wei Gao, Qing-Qing Pan, Yu-He Kan, Zhong-Min Su
Summary: This paper presents a series of radical luminescent materials based on TTM, designed through skeleton-engineering and periphery-engineering strategies. The study investigates the chemical stability and luminescence properties of these radicals using quantum chemistry methods. The findings reveal that radicals with smaller dihedral angle differences exhibit higher emission energy. Additionally, an efficient algorithm for calculating internal conversion rates is introduced and explained.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Hai-Ping Zhou, Shui-Xing Wu, Ying-Chen Duan, Feng-Wei Gao, Qing-Qing Pan, Yu-He Kan, Zhong-Min Su
Summary: This study investigates a series of monoradical molecules using quantum chemistry methods and finds that the luminescent properties of monoradical molecules can be tuned by introducing donor fragments. The electron donating abilities of donor fragments are negatively correlated with the stability and photoluminescence efficiency of the molecules. It is also discovered that the hybrid transition characteristic formed by charge transfer and localized excitation significantly contributes to the luminescence intensity of monoradical molecules.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Xue Bai, Shui-xing Wu, Ying-chen Duan, Qing-qing Pan, Feng-wei Gao, Yu-he Kan, Zhong-min Su
Summary: In this study, three new D-A-D molecules (PTZ-MPS, TPA-MPS, and PCz-MPS) were designed and investigated. It was found that PTZ-MPS has the feature of high-lying reverse intersystem crossing process, along with smaller singlet-triplet energy splitting and larger spin-orbital coupling strength.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Xingman Liu, Ronglin Zhong, Min Zhang, Shuixing Wu, Yun Geng, Zhongmin Su
DALTON TRANSACTIONS
(2019)
Article
Multidisciplinary Sciences
Ying Gao, Xiao-Dong Yang, Shui-Xing Wu, Yun Geng
ADVANCED THEORY AND SIMULATIONS
(2019)
Article
Chemistry, Multidisciplinary
Jian-Ji Zhong, Wai-Pong To, Yungen Liu, Wei Lu, Chi-Ming Che
Article
Chemistry, Multidisciplinary
Alexander M. Prophet, Kritanjan Polley, Gary J. Van Berkel, David T. Limmer, Kevin R. Wilson
Summary: The oxidation kinetics of iodide by ozone at the air-water interface is studied in single microdroplets. Molecular simulations and kinetic modeling are used to understand the underlying multiphase mechanism.
Article
Chemistry, Multidisciplinary
Rong Zhang, Jiajing Lan, Fei Wang, Shumei Chen, Jian Zhang
Summary: By utilizing 1,1'-ferrocene dicarboxylic acid as a chelating and surface protection ligand, we have synthesized multi-nuclear indium oxide clusters with varying nuclear sizes, including heptanuclear and thirteen-nuclear clusters. These clusters possess labile coordination sites, allowing for structural modification and self-assembly, resulting in the formation of various cluster structures.
Article
Chemistry, Multidisciplinary
Hui Wang, Hui Liu, Mingsen Wang, Jiaheng Hou, Yongjun Li, Yuancheng Wang, Yingjie Zhao
Summary: Two supramolecular complexes were prepared using CBs and M1, and their single-crystal structures were analyzed by SCXRD. The unexpected 1:2 self-assembly structure between M1 and CB[8] was discovered for the first time. These complexes exhibit unique photophysical properties and provide valuable information about the structure and photophysical properties of supramolecular complexes.
Article
Chemistry, Multidisciplinary
Chang-Hee Lee, Sookil Park, Sanggil Kim, Ji Young Hyun, Hyun Soo Lee, Injae Shin
Summary: The epidermal growth factor receptor (EGFR) is a cell-surface glycoprotein involved in cell proliferation and tumor development. This study used a fluorescently labeled EGFR to investigate its time-dependent endocytosis in live cells and found that appended glycans affect EGFR internalization. Additionally, the study detected sialic acid residues attached to EGFR on the live cell surface using FRET-based imaging. This research provides valuable insights into the cellular functions of EGFR.
Article
Chemistry, Multidisciplinary
Subhankar Sahu, Lokesh Kumar, Sumita Das, Dipti Gupta, Ruchi Anand
Summary: This study proposes a strategy that combines organic electronics with biosensor scaffolds to create a compact device for monitoring environmental aromatic pollution. By coupling biosensing protein MopR with an organic electrochemical transistor (OECT), a sensor module capable of efficient detection of phenol was designed. Exclusive phenol detection with minimal loss of sensitivity could be achieved in complex pollutant mixtures and real environmental samples.
Review
Chemistry, Multidisciplinary
Changseok Lee, Hyung-Joon Kang, Sungwoo Hong
Summary: The formation of C-N bonds through hydroamination reactions catalyzed by nickel hydrides has been a topic of recent interest. This approach offers a way to efficiently transform a variety of alkene and alkyne substrates into compounds enriched with C-N bonds. The review provides a concise overview of the underlying reaction mechanisms and aims to stimulate further progress in NiH-catalytic techniques and catalyst design.
Article
Chemistry, Multidisciplinary
Yueci Wu, Lu-Lu Sun, Hai-Hao Han, Xiao-Peng He, Weiguo Cao, Tony D. James
Summary: Drug-induced liver injury (DILI) is a common cause of acute liver failure in the USA and Europe, but most cases can be recovered or prevented by discontinuing the offending drug. Recent research has found that peroxynitrite (ONOO-) can be used as a potential indicator for early diagnosis of DILI, and there is an urgent need to establish a method to detect and track peroxynitrite in DILI cases. In this study, a FRET-based nano fluorescent probe CD-N-I was developed, which showed high selectivity and sensitivity in detecting peroxynitrite. The probe successfully detected exogenous peroxynitrite in live cells and endogenous peroxynitrite in APAP-induced liver injury of HepG2 cells.
Article
Chemistry, Multidisciplinary
Dmitry L. Lipilin, Mikhail O. Zubkov, Mikhail D. Kosobokov, Alexander D. Dilman
Summary: This article describes a direct photocatalytic method for the thiolation of unprotected acids, which was previously challenging. By using a thionocarbonate reagent with an N-O bond, the efficient conversion of carboxylic acids to thiols is achieved.
Article
Chemistry, Multidisciplinary
Jason Malenfant, Lucille Kuster, Yohann Gagne, Kouassi Signo, Maxime Denis, Sylvain Canesi, Mathieu Frenette
Summary: Raman microscopy can reveal compound-specific vibrational fingerprints without sample preparation. The combination of efficient theoretical calculations and a user-friendly software can accurately predict peak positions and provide match scores to assist with structure determination.
Article
Chemistry, Multidisciplinary
Jayoh A. Hernandez, Paul S. Micus, Sean Alec Lois Sunga, Luca Mazzei, Stefano Ciurli, Gabriele Meloni
Summary: Essential trace metals play crucial roles in the survival and virulence of bacterial pathogens. Helicobacter pylori requires nickel for colonization and persistence in the stomach, and NixA is an essential nickel transporter in this process. This study characterizes the selectivity and electrogenic nature of NixA-mediated nickel transport.
Article
Chemistry, Multidisciplinary
Tarali Devi, Kuheli Dutta, Jennifer Deutscher, Stefan Mebs, Uwe Kuhlmann, Michael Haumann, Beatrice Cula, Holger Dau, Peter Hildebrandt, Kallol Ray
Summary: This study emphasizes the importance of subtle electronic changes and secondary interactions in the stability of biologically relevant metal-dioxygen intermediates. It also shows that the role of the chloride ligand in stabilizing the Fe-III-(OOBu)-Bu-t moiety can extend to other anions, including the thiolate ligand.
Article
Chemistry, Multidisciplinary
Jacqueline R. Santhouse, Jeremy M. G. Leung, Lillian T. Chong, W. Seth Horne
Summary: By studying the folding kinetics and mechanism of the BdpA sequence, researchers found that altering the backbone connectivity can affect protein folding. This suggests that protein mimetic chains have a significant degree of plasticity in transitioning between unfolded and folded states.
Article
Chemistry, Multidisciplinary
Divanshu Gupta, Ralf Einholz, Holger F. Bettinger
Summary: This study presents the first direct spectroscopic evidence of a cyclic seven-membered iminoborane. Compared to linear amino-iminoboranes, this cyclic iminoborane exhibits weakened bond strength and lower Lewis acidity value. The study suggests that the reduced ring strain of cyclic iminoborane prevents nitrogen fixation but allows facile (2 + 2) cycloaddition reaction with C2H4.
Article
Chemistry, Multidisciplinary
Renny Mathew, Aniruddha Mazumder, Praveen Kumar, Julie Matula, Sharmarke Mohamed, Petr Brazda, Mahesh Hariharan, Brijith Thomas
Summary: This study reveals the packing arrangement of partially disordered nitro-perylenediimide (NO2-PDI) using a synergistic approach that combines 3D ED, ssNMR, and DFT techniques. By overcoming these challenges, this methodology opens up new avenues for material characterization, driving exciting advancements in the field.
