Combined α,α-dialkylprolinol ether/Brønsted acid promotes Mannich reactions of aldehydes with unactivated imines. An entry to anti-configured propargylic amino alcohols

Imidazolidinone-Derived Enamines: Nucleophiles with Low Reactivity

(2012) Sami Lakhdar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A walk around the A3-coupling

(2012) Vsevolod A. Peshkov et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric Michael Addition of N-Boc-Protected Oxindoles to Nitroalkenes Catalyzed by a Chiral Secondary Amine

(2012) Chuan Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Diarylprolinol Silyl Ether System: A General Organocatalyst

(2011) Kim L. Jensen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Gold-Catalyzed Carbon−Heteroatom Bond-Forming Reactions

(2011) A. Corma et al.   CHEMICAL REVIEWS

Advances in the Chemistry of Tetrahydroquinolines

(2011) Vellaisamy Sridharan et al.   CHEMICAL REVIEWS

Catalytic Enantioselective Formation of C−C Bonds by Addition to Imines and Hydrazones: A Ten-Year Update

(2011) Shu̅ Kobayashi et al.   CHEMICAL REVIEWS

Asymmetric Mannich Reaction of Imines Derived from Aliphatic and Aromatic Aldehydes Catalyzed by Diarylprolinol Silyl Ether

(2011) Tatsuya Urushima et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Active Organocatalysts for Asymmetric anti-Mannich Reactions

(2011) Rafael Martín-Rapún et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantio- and Diastereoselective Organocatalytic α-Alkylation of Aldehydes with 3-Substituted 2-(Bromomethyl)acrylates

(2011) Jacqueline Jiménez et al.   JOURNAL OF ORGANIC CHEMISTRY

Formation and Stability of Prolinol and Prolinol Ether Enamines by NMR: Delicate Selectivity and Reactivity Balances and Parasitic Equilibria

(2011) Markus B. Schmid et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantification of the Electrophilic Reactivities of Aldehydes, Imines, and Enones

(2011) Roland Appel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective synthesis of cyclic carbamimidates via a three-component reaction of imines, terminal alkynes, and p-toluenesulfonylisocyanate using a monophosphine gold(i) catalyst

(2011) Matthew J. Campbell et al.   Chemical Science

The Development of Catalytic Nucleophilic Additions of Terminal Alkynes in Water†

(2010) Chao-Jun Li   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Synthesis with Silicon-Based Bulky Amino Organocatalysts

(2010) Li-Wen Xu et al.   ADVANCED SYNTHESIS & CATALYSIS

(S)-Indoline-3-Carboxylic Acid: A New Organocatalyst for the Anti Mannich-Type Reaction

(2010) Jörg Pietruszka et al.   ChemCatChem

Efficient and Highly Enantioselective Michael Addition of Aldehydes to Nitroalkenes Catalyzed by a Surfactant-type Organocatalyst in the Presence of Water

(2010) Feng Hu et al.   CHEMISTRY LETTERS

Copper-Catalyzed Enantioselective Three-Component Synthesis of Optically Active Propargylamines from Aldehydes, Amines, and Aliphatic Alkynes

(2010) Shuichi Nakamura et al.   CHEMISTRY-A EUROPEAN JOURNAL

Controlling Stereoselectivity in the Aminocatalytic Enantioselective Mannich Reaction of Aldehydes with In Situ Generated N-Carbamoyl Imines

(2010) Patrizia Galzerano et al.   CHEMISTRY-A EUROPEAN JOURNAL

A 4-Hydroxypyrrolidine-Catalyzed Mannich Reaction of Aldehydes: Control ofanti-Selectivity by Hydrogen Bonding Assisted by Brønsted Acids

(2010) Enrique Gómez-Bengoa et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Enantioselective Addition of Alkyne Nucleophiles to Carbonyl Groups

(2009) Barry M. Trost et al.   ADVANCED SYNTHESIS & CATALYSIS

4-Aminothiourea Prolinoltert-Butyldiphenylsilyl Ether: A Chiral Secondary Amine-Thiourea as Organocatalyst for Enantioselectiveanti-Mannich Reactions

(2009) Hui Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

A Designer Axially Chiral Amino Sulfonamide as an Efficient Organocatalyst for Direct Asymmetric Mannich Reactions of N-Boc-Protected Imines

(2009) Taichi Kano et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Proline-Catalyzed Double Mannich Reaction of Acetaldehyde withN-Boc Imines

(2009) Carley Chandler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Addition of Boronates to Acyl Imines Catalyzed by Chiral Biphenols

(2009) Joshua A. Bishop et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Alkynylation of Imines by Cooperative Hydrogen Bonding and Metal Catalysis

(2009) Pedro de Armas et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conjugated imines and iminium salts as versatile acceptors of nucleophiles

(2009) Makoto Shimizu et al.   CHEMICAL COMMUNICATIONS

Organocatalysis—after the gold rush

(2009) Søren Bertelsen et al.   CHEMICAL SOCIETY REVIEWS

Catalytic asymmetric direct Mannich reaction: a powerful tool for the synthesis of α,β-diamino acids

(2009) Ramón Gómez Arrayás et al.   CHEMICAL SOCIETY REVIEWS

Recent Developments in Asymmetric Alkynylation of Imines

(2009) G. Blay et al.   CURRENT ORGANIC CHEMISTRY

Organocatalyticanti-Selective Mannich Reactions with Fluorinated Aldimines: Synthesis ofanti-γ-Fluoroalkyl-γ-amino Alcohols

(2009) Santos Fustero et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Structures of the Reactive Intermediates in Organocatalysis with Diarylprolinol Ethers

(2009) Uroš Grošelj et al.   HELVETICA CHIMICA ACTA

Hydrogen-Bonding Asymmetric Metal Catalysis with α-Amino Acids: A Simple and Tunable Approach to High Enantioinduction

(2009) Yingdong Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One-pot highly enantioselective catalytic Mannich-type reactions between aldehydes and stable α-amido sulfones: asymmetric synthesis of β-amino aldehydes and β-amino acids

(2009) Luca Deiana et al.   TETRAHEDRON LETTERS

Direct Organocatalytic Mannich Reaction of Acetaldehyde: An Improved Catalyst and Mechanistic Insight from a Computational Study

(2008) Yujiro Hayashi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Reactions with Acetaldehyde

(2008) Benito Alcaide et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aminocatalytic Enantioselectiveanti-Mannich Reaction of Aldehydes with In Situ GeneratedN-Cbz andN-Boc Imines

(2008) Chiara Gianelli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Zinc/Binol-Catalyzed Alkynylation of N -Sulfonyl Aldimines

(2008) Gonzalo Blay et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Proline-Catalyzed Highly Enantioselective andanti-Selective Mannich Reaction of Unactivated Ketones: Synthesis of Chiral α-Amino Acids

(2008) Björn T. Hahn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Aminocatalysis-Gold Rush in Organic Chemistry

(2008) Paolo Melchiorre et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalysis: From Infancy to Adolescence

(2008) Alessandro Dondoni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Coinage Metal-Assisted Synthesis of Heterocycles

(2008) Nitin T. Patil et al.   CHEMICAL REVIEWS

Copper-Catalyzed Asymmetric Alkylation of Imines with Dialkylzinc and Related Reactions

(2008) Ken-ichi Yamada et al.   CHEMICAL REVIEWS

α,α-Diarylprolinol Ethers: New Tools for Functionalization of Carbonyl Compounds

(2008) Antonia Mielgo et al.   Chemistry-An Asian Journal

Proline-catalysed Mannich reactions of acetaldehyde

(2008) Jung Woon Yang et al.   NATURE

3-Trifluoromethanesulfonamido-pyrrolidine:  A General Organocatalyst foranti-Selective Mannich Reactions

(2008) Mickael Pouliquen et al.   ORGANIC LETTERS

Organocatalysed asymmetric Mannich reactions

(2007) Jorge M. M. Verkade et al.   CHEMICAL SOCIETY REVIEWS

Catalysis of 3-Pyrrolidinecarboxylic Acid and Related Pyrrolidine Derivatives in Enantioselectiveanti-Mannich-Type Reactions:  Importance of the 3-Acid Group on Pyrrolidine for Stereocontrol

(2007) Haile Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

anti-Selective direct asymmetric Mannich reactions catalyzed by chiral pyrrolidine-based amino sulfonamides

(2007) Taichi Kano et al.   TETRAHEDRON