Article
Chemistry, Physical
Heng Zhang, Jing Xiao, Yan Wang, Lian Zhang, Guohui Zhao, Hongfang Yang, Huan Wang
Summary: Breath analysis using gas sensors is an important supplementary method for early disease diagnosis. This study investigates the feasibility of detecting acetone concentration in exhaled breath using a SmFeO3-based sensor and establishes a mathematical model to remove the effects of carbon dioxide and relative humidity. Volunteer studies validate the accuracy of this mathematical model. A portable acetone detector based on the SmFeO3 sensor is designed and proves to be feasible and effective in accurately detecting acetone concentration in exhaled breath through experiments with volunteers.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Multidisciplinary
Di Wang, Fenni Zhang, Amlendu Prabhakar, Xingcai Qin, Erica S. Forzani, Nongjian Tao
Summary: Breath acetone (BrAce) is a validated biomarker of lipid oxidation and has been extensively studied for various applications, such as monitoring ketoacidosis in diabetes. While many sensors have been reported for BrAce measurement, most only tested synthetic or spiked breath samples. A colorimetric sensor has been shown to achieve online accurate detection of BrAce.
Review
Engineering, Electrical & Electronic
Yusra Obeidat
Summary: Studies have shown a correlation between volatile acetone in breath and ketone bodies in blood, making breath analysis an attractive method for diagnosing diabetes. There is a need for affordable, easy to use, and accurate monitoring devices to help individuals with diabetes.
IEEE SENSORS JOURNAL
(2021)
Article
Biophysics
Xin Li, Jingying Pan, Yue Wu, Huan Xing, Zijian An, Zhenghan Shi, Jingjiang Lv, Fenni Zhang, Jing Jiang, Di Wang, Ray P. S. Han, Bin Su, Yanli Lu, Qingjun Liu
Summary: A wireless facemask based on Ti3C2Tx MXene is developed for the noninvasive monitoring of breath acetone (BrAC) and real-time tracking of lipid metabolism. The facemask can not only detect acetone but also filter out breath interference. It is integrated with a miniaturized flexible detection tag for easy BrAC detection and wireless data transmission. The system enables detection of BrAC down to 0.31 ppm in breath.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Tong Liu, Haifei Guan, Tong Wang, Xishuang Liang, Fengmin Liu, Fangmeng Liu, Chuan Zhang, Geyu Lu
Summary: Breath analysis is crucial for early diagnosis of diabetic ketoacidosis. Gas sensors with Bi1-xSrxFeO3 materials were used to fabricate sensors, showing potential in clinical tests for diabetes and healthy individuals.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Arpit Verma, Deepankar Yadav, Ajeet Singh, Monu Gupta, K. B. Thapa, B. C. Yadav
Summary: This study found that the analysis of volatile organic compounds in exhaled breath can be used as a non-invasive monitoring tool for diabetes patients. The study reports the development of a quick responsive and highly sensitive acetone biosensor based on the perovskite BaSnO3. The sensor showed fast response time and high sensitivity.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Review
Chemistry, Multidisciplinary
Qasem A. Drmosh, Ibrahim Olanrewaju Alade, Mohammad Qamar, Sheikh Akbar
Summary: Acetone is a toxic, explosive, and harmful gas, also serving as a key biomarker for diagnosing diseases and monitoring human health disorders. ZnO-based sensors, with their high stability and low cost, show great potential for acetone gas detection.
CHEMISTRY-AN ASIAN JOURNAL
(2021)
Article
Chemistry, Analytical
Andreas T. Guntner, Ines C. Weber, Stephanie Schon, Sotiris E. Pratsinis, Philipp A. Gerber
Summary: Tracking breath acetone changes using breath sensors can accurately detect the early onset of metabolic diseases. This method is important for personalized treatment, but selective monitoring of breath markers remains challenging.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Engineering, Electrical & Electronic
Sara Boumali, Mohamed Taoufik Benhabiles, Ahmed Bouziane, Fouad Kerrour, Khalifa Aguir
Summary: This study successfully developed an electronic nose for non-invasive blood glucose monitoring, utilizing homemade gas sensors exposed to acetone and ethanol. Through feature extraction, selection, and classification, the system achieved 100% accuracy in estimating gas concentrations with a root mean square error of 0.2236 and 0.6639 for acetone and ethanol, respectively.
SEMICONDUCTOR SCIENCE AND TECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Nicola Brew-Sam, Jane Desborough, Anne Parkinson, Krishnan Murugappan, Eleni Daskalaki, Ellen Brown, Harry Ebbeck, Lachlan Pedley, Kristal Hannon, Karen Brown, Elizabeth Pedley, Genevieve Ebbeck, Antonio Tricoli, Hanna Suominen, Christopher J. Nolan, Christine Phillips
Summary: This study aimed to understand the design preferences of young people with T1DM and their parents for breath ketone sensors to inform the development of a prototype that best suits their diabetes management needs. The results showed that breath ketone sensors have the potential to facilitate ketone testing in young people with T1DM, and important design features include portability, ease of use, reliability, suitability, and sustainability.
Article
Chemistry, Analytical
Li Jiang, Siyuan Lv, Wanqing Tang, Lianjing Zhao, Caileng Wang, Jing Wang, Tianshuang Wang, Xinrui Guo, Fangmeng Liu, Chenguang Wang, Peng Sun, Chuan Zhang, Jie Zheng, Geyu Lu
Summary: Breath analysis using gas sensors, particularly acetone sensors, plays a crucial role in pre-diagnosis of diabetes. The developed mixed potential type acetone sensor shows excellent sensitivity and stability, with strong correlations established among response values, acetone concentrations, and blood ketone concentrations for pre-diagnosis of diabetes.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Physical
Jingjing Zheng, Xiaotian Li, Bo Zhang, Xiaoxin Zou, Qihua Liang, Hui Chen, Guo-Dong Li
Summary: Pt-decorated foam-like Ga-In bimetal oxide nanofibers show enhanced sensing response towards acetone detection, with high response, low detection limit, short response time, and high moisture resistance.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Chemistry, Analytical
Anna Paleczek, Dominik Grochala, Artur Rydosz
Summary: Exhaled breath analysis has gained popularity as a supplementary tool for medical diagnosis, leading researchers to develop new algorithms for data interpretation. This paper introduces a system for analyzing exhaled air with sensors and presents the XGBoost algorithm for diabetes detection. Results demonstrate that the XGBoost algorithm is highly selective and performs better than other commonly used algorithms.
Article
Engineering, Electrical & Electronic
Hongchao Zhao, Jing Li, Yanjie Wang, Ruijie Zhang, Cheng Zou, Yong Zhou
Summary: This study utilized chemoresistive MEMS acetone sensors with a sensing layer of black phosphorus (BP) nanosheets-modified zinc ferrite spheres for sensitive and swift acetone detection. The sensors exhibited excellent selectivity, repeatability, and long-term stability, as well as twofold response enhancement and stronger sensitivity compared to pure zinc ferrite analog.
IEEE SENSORS JOURNAL
(2023)
Review
Chemistry, Analytical
Omar Alkedeh, Ronny Priefer
Summary: The ketogenic diet is now commonly used for weight loss by restricting carbohydrate intake to promote fat burning. Breath and blood ketone levels can be measured to gauge the level of ketosis and adjust the diet accordingly. Breath acetone sensors are becoming more common due to less invasiveness and convenience, with new technologies being researched to capitalize on the popularity of the diet.
Article
Chemistry, Physical
Joshua D. Butson, Astha Sharma, Hongjun Chen, Yuan Wang, Yonghwan Lee, Purushothaman Varadhan, Mihalis N. Tsampas, Chuan Zhao, Antonio Tricoli, Hark Hoe Tan, Chennupati Jagadish, Siva Karuturi
Summary: The use of surface-structured cocatalyst foils allows for fully decoupled catalytic interfaces, achieving high efficiency and long-term stability for photoelectrodes in solar water splitting systems. The cocatalyst foils provide outstanding protection for the chemical-sensitive photoabsorbers, enabling stable photocurrent generation over multiple days and high solar-to-hydrogen efficiency in immersed systems. This approach presents a promising method for fabricating high-performance solar water splitting systems.
ADVANCED ENERGY MATERIALS
(2022)
Article
Chemistry, Physical
Borui Liu, Juan F. Torres, Mahdiar Taheri, Pan Xiong, Teng Lu, Junwu Zhu, Yun Liu, Guihua Yu, Antonio Tricoli
Summary: This study introduces a dual-ion flux management strategy to control the distribution of Li and polysulfide ions in high-energy Li-S batteries. By using a multiscale membrane with multiple functionalities, it enables long-term use of high S-loading cathodes with good cycling performance.
ADVANCED ENERGY MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Kiara Bruggeman, Meng Zhang, Nicolo Malagutti, Shiva Soltani Dehnavi, Richard Williams, Antonio Tricoli, David Nisbet
Summary: Nanoparticles are commonly used as delivery vehicles for drugs, but their diffusion often leads to inconsistent drug release. In this study, brain-derived neurotrophic factor (BDNF) is attached to photoactive titanium dioxide nanoparticles and loaded into a nanofibrous self-assembling peptide (SAP) hydrogel. By manipulating UV exposure conditions, the researchers were able to achieve a more constant and flattened drug release profile. The adsorption of the growth factor onto the hydrogel nanofibers and the interaction between the released growth factor and the hydrogel were found to affect the drug release. This study demonstrates the potential for precise control of drug release by manipulating the amount of bound growth factor on the nanoparticles and provides insights into the diffusion and release behavior of nanoparticles in hydrogels.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Monalisha Ghosh Dastidar, Krishnan Murugappan, Adam M. Damry, David R. Nisbet, Christopher J. Nolan, Antonio Tricoli
Summary: The development of biosensors is crucial for controlling the spread of potential pandemics and decentralizing healthcare services. This study presents an efficient material platform for detecting biomarkers at extremely low concentrations with excellent selection and a wide linear response range, showcasing its potential for clinical utility and versatility in detecting other biomarkers.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Review
Chemistry, Multidisciplinary
Buddini Karawdeniya, Adam M. Damry, Krishnan Murugappan, Shridhar Manjunath, Y. M. Nuwan D. Y. Bandara, Colin J. Jackson, Antonio Tricoli, Dragomir Neshev
Summary: Optical metasurfaces have been widely used in sensing applications due to their unique optical properties. Surface modification techniques, such as chemical functionalization and physical texturing, can enhance the specificity and performance of metasurfaces. This review summarizes recent advances in this field and provides detailed guidance for implementation.
Article
Chemistry, Multidisciplinary
Deepu Ashok, Mahdiar Taheri, Puneet Garg, Daryl Webb, Pawan Parajuli, Yi Wang, Bronte Funnell, Bradley Taylor, David C. Tscharke, Takuya Tsuzuki, Naresh K. Verma, Antonio Tricoli, David R. Nisbet
Summary: This article reports on a sprayable coating that has the ability to resist the uptake and transmission of bacteria and viruses, while also providing bactericidal functionality and reducing viral contamination.
Article
Nanoscience & Nanotechnology
Thanh Tran-Phu, Hongjun Chen, Rahman Daiyan, Manjunath Chatti, Borui Liu, Rose Amal, Yun Liu, Douglas R. Macfarlane, Alexandr N. Simonov, Antonio Tricoli
Summary: The addition of a dielectric nanoscale-thin layer made of amorphous TiO2 on low-cost Co3O4 nanostructured anodes enhances their stability and electrocatalytic activity for oxygen evolution reaction (OER). An optimal thickness of 4.4 nm for the TiO2 layer improves the anode lifetime by a factor of approximately 3, enabling 80 hours of continuous electrolysis at near-zero pH while maintaining high OER catalytic activity.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Energy & Fuels
Sahar Hosseini, Juan F. Torres, Mahdiar Taheri, Antonio Tricoli, Wojciech Lipinski, Joe Coventry
Summary: Pyromark 2500 is commonly used as an absorber coating in concentrating solar power systems due to its high absorptance and ease of application, but it degrades significantly at elevated temperatures and eventually fails without costly maintenance. Research on Pyromark degradation reveals that optical stability and failure mechanisms are influenced by aging temperature and material properties, with spallation identified as the main physical degradation mechanism.
SOLAR ENERGY MATERIALS AND SOLAR CELLS
(2022)
Review
Chemistry, Physical
Xuan Minh Chau Ta, Rahman Daiyan, Thi Kim Anh Nguyen, Rose Amal, Thanh Tran-Phu, Antonio Tricoli
Summary: This review presents recent progress on alternative anodic choices for photoelectrochemical water splitting, discusses the benefits and issues of alternative photooxidation reactions coupled with concurrent hydrogen evolution reaction, and evaluates the challenges and opportunities of these alternative reactions for solar energy production and environmental treatment.
ADVANCED ENERGY MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Shiyu Wei, Zhe Li, Krishnan Murugappan, Ziyuan Li, Fanlu Zhang, Aswani Gopakumar Saraswathyvilasam, Mykhaylo Lysevych, Hark Hoe Tan, Chennupati Jagadish, Antonio Tricoli, Lan Fu
Summary: The rapid development of IoT has led to an increasing demand for self-powered gas sensors for real-time data collection and autonomous responses in various industries. However, most reported self-powered devices, particularly NO2 sensors for air pollution monitoring, have limitations in sensitivity, selectivity, and scalability. In this study, a novel photovoltaic self-powered NO2 sensor based on InP nanowire arrays is demonstrated, which overcomes these limitations. The sensor achieves a high sensing response and low detection limit even under low light intensity, and shows promising performance in dynamic environmental monitoring of motor vehicle exhaust.
ADVANCED MATERIALS
(2023)
Article
Engineering, Environmental
Monalisha Ghosh Dastidar, Ulrike Schumann, Teng Lu, Yun Liu, David R. Nisbet, Riccardo Natoli, Krishnan Murugappan, Antonio Tricoli
Summary: Electrochemical aptasensors are a versatile tool for detecting miRNA biomarkers associated with several diseases. However, most aptasensors require complex surface and probe modifications to achieve high sensitivity and selectivity. In this study, a simple and highly sensitive electrochemical aptasensor architecture is introduced for the rapid detection of miRNA. The analytical utility of this aptasensor in mouse serum suggests its immediate potential for clinical applications like macular degeneration screening.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Materials Science, Multidisciplinary
Xuan Minh Chau Ta, Thi Kim Anh Nguyen, Anh Dinh Bui, Hieu T. T. Nguyen, Rahman Daiyan, Rose Amal, Thanh Tran-Phu, Antonio Tricoli
Summary: Photoelectrochemical water splitting is a promising approach to produce green hydrogen using solar energy. However, the lack of efficient photoanodes to catalyze the water photooxidation reaction remains a challenge. In this study, nanostructured FeWO4 photoanodes were synthesized on a fluorine doped tin oxide glass substrate via a scalable and ultra-fast flame synthesis route. The optimized FeWO4 photoanode with a bandgap of 1.82 eV and a FeOOH/NiOOH co-catalyst coating showed improved water photooxidation performance and good photostability, providing insights for the engineering of small band-gap catalysts for various photoelectrochemical applications.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Chemistry, Multidisciplinary
Thanh Tran-Phu, Manjunath Chatti, Joshua Leverett, Thi Kim Anh Nguyen, Darcy Simondson, Dijon A. Hoogeveen, Alexander Kiy, The Duong, Bernt Johannessen, Jaydon Meilak, Patrick Kluth, Rose Amal, Alexandr N. Simonov, Rosalie K. Hocking, Rahman Daiyan, Antonio Tricoli
Summary: To decrease the cost of hydrogen production and unlock the potential of the hydrogen economy, highly active and durable catalysts for oxygen and hydrogen evolution reactions are needed. This study reports a scalable strategy to prepare doped cobalt oxide electrocatalysts that enhance the activity of these reactions in alkaline conditions. The doping elements increase the bulk conductivity and density of redox active sites without altering the reaction mechanisms. These findings provide insights for engineering Co3O4 as a low-cost material for green hydrogen electrocatalysis at large scales.
Article
Nanoscience & Nanotechnology
Zain Ul Abideen, Jun-Gyu Choi, Jodie A. A. Yuwono, Alexander Kiy, Priyank Vijaya Kumar, Krishnan Murugappan, Won-June Lee, Patrick Kluth, David R. R. Nisbet, Thanh Tran-Phu, Myung-Han Yoon, Antonio Tricoli
Summary: A strategy to enhance the performance of semiconductor sensors by engineering tunable oxygen vacancies in thick metal oxide nanoparticles networks is proposed. This approach achieves high selectivity and sensitivity by optimizing the electronic structure and surface activity while maintaining a 3D morphology. The introduction of oxygen vacancies results in significant improvement in the sensitivity, response time, and recovery time of ZnO sensors for detecting ethanol at room temperature. The presence of oxygen vacancies also enables a low limit of detection at an operating temperature of 150°C. This scalable approach has the potential for developing wearable chemical and bio-sensors and tuning the activity and band structure of oxide films for various applications.
ADVANCED ELECTRONIC MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Krishnan Murugappan, Uthayasuriya Sundaramoorthy, Adam M. Damry, David R. Nisbet, Colin J. Jackson, Antonio Tricoli
Summary: Electrochemical biosensors are useful tools for detecting biological parameters, but they often struggle with selectively and sensitively detecting small molecules. In this study, we developed a new electrochemical biosensing platform that amplifies the redox signal generated by analyte binding using conformational changes of solute-binding proteins. We successfully constructed biosensors for leucine and glycine detection, which exhibited selective and sensitive detection over a wide range of concentrations. The selectivity of these sensors can also be easily modified by changing the binding domain of the bioreceptor.
